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The map label for this gene is hslO

Identifier: 197119915

GI number: 197119915

Start: 4069019

End: 4069906

Strand: Direct

Name: hslO

Synonym: Gbem_3554

Alternate gene names: 197119915

Gene position: 4069019-4069906 (Clockwise)

Preceding gene: 197119914

Following gene: 197119916

Centisome position: 88.17

GC content: 61.15

Gene sequence:

>888_bases
ATGACCGATTATCTAGTTCGTGCGATTGCCAAATCGGGGAGCGTCAGGGCCCTTGCCTGTGTCACCACGGCAACCGTCGG
CGCGATATGCAAACGCCACGATACCTTACCCACCGCTACGGCCGCGCTGGGAAGAGGGATAACGGCAGGTGCTCTCATGG
GGGCCCTCTTGAAGACCGGGCAGCGGGTCGCCATGCGTTTCGAGGGGAACGGCCCCCTCAAGAAGATCGTCATCGAAGCC
GACGCTAACGGCAGCGTCCGAGGTTACGTCGGAGACCCGAAGGTCCACCTGCTGCGTCCGGACGGGGCATTGGACGTGAA
CAACGCGCTGGGGCGCGCCGGCTTTCTCACCGTCGCCAAGGATCTCGGGCTCAAAGAGCCGTATCGCGGCACCGTGCAGC
TCTATACCAGCGGCATCGCCGAGGACCTGGCCCTCTACCTGGTGGAAAGCGAGCAGATACCGTCCGCAGTAGGCATCGCC
GAGTTCATCGAGCAGGACGGCACCGTAGCCGCAGCCGGGGGATTCCTGATCCAGGCAGTGCCGCCGGTCGACCCACTGGT
GATCGAGGAGCTGATGACGCGGATAGAGCAACTGCCGCCCTTAAGCGAGTTGCTGCACAAAGGAGGCAATCCCGAGCAGA
TTCTGGAGCAGCTTCTTGCCGGCATCCCCTACGACATCCTGGAGAAGAGGAACATAGCGTTTGCCTGCAGTTGCAGCCGC
GAGCGGATTGAGCGCGTCCTTCTCTCCATGGGGAAGAAAGAACTGAGTTCCATGAAGAAAGATCAGCACGGAAGCGAAGT
GACCTGCGAGTTCTGCGGCGAGCATTACCTTTTCGACGAGGCCGACCTCGACCGGATCATAGCCGAGATCGCAAAGCAGG
AAGGTTAG

Upstream 100 bases:

>100_bases
TCGCGCAGCGGGTAAAGGGGATCAGCATCTGGGACTTTATAACCCTCAAGGAGCTTTGGCTTAGAAAGGGTGAAATCGTA
GGAAGGGTGGGGGTGGTACT

Downstream 100 bases:

>100_bases
GGCTAAGAAGCAGAAAAGCAGGAAGACTAGCTCGGAGTTATAGCCTCTTCCTTGAGGGAGGAGGGGCCACAGCTGAACGT
TCCGCGGAATAAGGGGGGAT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTDYLVRAIAKSGSVRALACVTTATVGAICKRHDTLPTATAALGRGITAGALMGALLKTGQRVAMRFEGNGPLKKIVIEA
DANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAKDLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIA
EFIEQDGTVAAAGGFLIQAVPPVDPLVIEELMTRIEQLPPLSELLHKGGNPEQILEQLLAGIPYDILEKRNIAFACSCSR
ERIERVLLSMGKKELSSMKKDQHGSEVTCEFCGEHYLFDEADLDRIIAEIAKQEG

Sequences:

>Translated_295_residues
MTDYLVRAIAKSGSVRALACVTTATVGAICKRHDTLPTATAALGRGITAGALMGALLKTGQRVAMRFEGNGPLKKIVIEA
DANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAKDLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIA
EFIEQDGTVAAAGGFLIQAVPPVDPLVIEELMTRIEQLPPLSELLHKGGNPEQILEQLLAGIPYDILEKRNIAFACSCSR
ERIERVLLSMGKKELSSMKKDQHGSEVTCEFCGEHYLFDEADLDRIIAEIAKQEG
>Mature_294_residues
TDYLVRAIAKSGSVRALACVTTATVGAICKRHDTLPTATAALGRGITAGALMGALLKTGQRVAMRFEGNGPLKKIVIEAD
ANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAKDLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIAE
FIEQDGTVAAAGGFLIQAVPPVDPLVIEELMTRIEQLPPLSELLHKGGNPEQILEQLLAGIPYDILEKRNIAFACSCSRE
RIERVLLSMGKKELSSMKKDQHGSEVTCEFCGEHYLFDEADLDRIIAEIAKQEG

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=286, Percent_Identity=27.6223776223776, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_GEOBB (B5EC90)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002140342.1
- ProteinModelPortal:   B5EC90
- SMR:   B5EC90
- GeneID:   6780417
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_3554
- HOGENOM:   HBG286231
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31613; Mature: 31482

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYLVRAIAKSGSVRALACVTTATVGAICKRHDTLPTATAALGRGITAGALMGALLKTG
CHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHCC
QRVAMRFEGNGPLKKIVIEADANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAK
CEEEEEECCCCCEEEEEEEECCCCCEEEEECCCEEEEECCCCCCCCHHHHCHHHHHHHHH
DLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIAEFIEQDGTVAAAGGFLIQAV
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEC
PPVDPLVIEELMTRIEQLPPLSELLHKGGNPEQILEQLLAGIPYDILEKRNIAFACSCSR
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEEEECCCH
ERIERVLLSMGKKELSSMKKDQHGSEVTCEFCGEHYLFDEADLDRIIAEIAKQEG
HHHHHHHHHHCHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TDYLVRAIAKSGSVRALACVTTATVGAICKRHDTLPTATAALGRGITAGALMGALLKTG
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHCC
QRVAMRFEGNGPLKKIVIEADANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAK
CEEEEEECCCCCEEEEEEEECCCCCEEEEECCCEEEEECCCCCCCCHHHHCHHHHHHHHH
DLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIAEFIEQDGTVAAAGGFLIQAV
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEECCCEEEEEC
PPVDPLVIEELMTRIEQLPPLSELLHKGGNPEQILEQLLAGIPYDILEKRNIAFACSCSR
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEEEECCCH
ERIERVLLSMGKKELSSMKKDQHGSEVTCEFCGEHYLFDEADLDRIIAEIAKQEG
HHHHHHHHHHCHHHHHHHHHHCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA