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The map label for this gene is tolB [H]

Identifier: 197119875

GI number: 197119875

Start: 4024494

End: 4025717

Strand: Direct

Name: tolB [H]

Synonym: Gbem_3513

Alternate gene names: 197119875

Gene position: 4024494-4025717 (Clockwise)

Preceding gene: 197119874

Following gene: 197119876

Centisome position: 87.2

GC content: 64.3

Gene sequence:

>1224_bases
ATGAGAATAATATTGCTGTTGGCCATGCTGCTCCTGGCGCCTCAAATGGCGCAGGCGGCAGAGGGATATATAGACGTAAC
GGCCCCGGTGAGCCGCAAGCTCAAGCTCTTCCCGGCTCCCGCCACCGGCCTCGCCGGGCAGGTGCCCCCGGAGGTGTCCA
GGGAGCTCTCCGAGCTGTTCGGGATGGACCTGGGATTAGCCGGCCCCTTCGAGGTCTCCGGGGACGGCGCGGGCGCCGAC
CTGATCCTGAAAAGTTCCTACAGCGCGCAGGGGGGCAACATCACCCTGGAGTGCCGACTGGTGGACCGGGTGCTGAACCG
CGAGATCACCGCCAAGCGCTACAGCGGGTCAGCGAAGGAATTACGCCGCATGGGGCACGCCTTCTCCGACGAGGTGCTGC
GCGCGGTGACCGGGGAAAAAGGTCCCTTCACCGGCAAGATCGCCTACGTGACCAAGGCCTCCGGCAACAAGGAGATCTTC
GTCATGGACTACGACGGGCACAACCCGCAGAGGCTCACCAACAACGGCTCCATCAACCTGAACCCCGACTTCGCCCCCTC
CGGCAAGGAGATCATCTACACCTCCTACAAGAAAGGGAACCCGGACCTGTACCGCCGCGAACTCTTCACCGGGCTCGAGG
CGCGCATCTCCTCCCGAAGCGGCCTGAACGCCACGGGCGCCTACTCCCCAGACGGCAGCAAGATAGCCATGGTGATGAGC
AAGGACGGCAATTCCGAGATCTACCTGATCTCGCGGGAAGGAAAGGAGCTGGCGCGGCTCACCAACAACCACGCCATCGA
CGTCTCCCCGGCCTGGTCGCCGGACGGCTCCCGCATCGTCTTCGTCTCCGACCGCCTGGGCAAACCTCAGGTGTTCATAA
TGAATGCGGACGGCGGCAACGTGCACCGGCTCACCGCCAACGGCGCCTACAACGTCACGCCCCGCTGGTCGCCCAAAGGG
GACCGGATCGTGTACGCGCGCCAGGGAGGAGGCGGGTTCCAGATCTACGCCATCAATGCGGACGGCACCCAGGACACCCA
ACTCACCAGCGCAGGTAGCAACGAGCACCCCCGCTTCTCGCCGGACGGCCGCTTCATCGTCTTCAGCTCCACCCGCGACG
GCGCCGAGGCGATCTACCTGATGCGCGCCGACGGAAGCGGCCAGACCAGGGTATCCCCCAACAAGTCCCAGAATTCCCAT
CCGACATGGTCGGTAAATTGGTAA

Upstream 100 bases:

>100_bases
ATCGGGCCGTGACGCTGGCCGGCAAATCGCTGGTCCCACCGCCGGGCGGCGCGCCGTTCAAGCGCATGTTCCGCTTCAGA
CCGGAAGGGGTCGGTATCAG

Downstream 100 bases:

>100_bases
AGATACCGGTACATTTTGAATCATTGATTAACTCGGAAAAGGTGAGTATACTTTCCTTCGCTTTTTAACCACGGCACGCT
CATGAGGAGCGGCACGTATT

Product: TolB-like biopolymer transport periplasmic beta-propeller repeat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRIILLLAMLLLAPQMAQAAEGYIDVTAPVSRKLKLFPAPATGLAGQVPPEVSRELSELFGMDLGLAGPFEVSGDGAGAD
LILKSSYSAQGGNITLECRLVDRVLNREITAKRYSGSAKELRRMGHAFSDEVLRAVTGEKGPFTGKIAYVTKASGNKEIF
VMDYDGHNPQRLTNNGSINLNPDFAPSGKEIIYTSYKKGNPDLYRRELFTGLEARISSRSGLNATGAYSPDGSKIAMVMS
KDGNSEIYLISREGKELARLTNNHAIDVSPAWSPDGSRIVFVSDRLGKPQVFIMNADGGNVHRLTANGAYNVTPRWSPKG
DRIVYARQGGGGFQIYAINADGTQDTQLTSAGSNEHPRFSPDGRFIVFSSTRDGAEAIYLMRADGSGQTRVSPNKSQNSH
PTWSVNW

Sequences:

>Translated_407_residues
MRIILLLAMLLLAPQMAQAAEGYIDVTAPVSRKLKLFPAPATGLAGQVPPEVSRELSELFGMDLGLAGPFEVSGDGAGAD
LILKSSYSAQGGNITLECRLVDRVLNREITAKRYSGSAKELRRMGHAFSDEVLRAVTGEKGPFTGKIAYVTKASGNKEIF
VMDYDGHNPQRLTNNGSINLNPDFAPSGKEIIYTSYKKGNPDLYRRELFTGLEARISSRSGLNATGAYSPDGSKIAMVMS
KDGNSEIYLISREGKELARLTNNHAIDVSPAWSPDGSRIVFVSDRLGKPQVFIMNADGGNVHRLTANGAYNVTPRWSPKG
DRIVYARQGGGGFQIYAINADGTQDTQLTSAGSNEHPRFSPDGRFIVFSSTRDGAEAIYLMRADGSGQTRVSPNKSQNSH
PTWSVNW
>Mature_407_residues
MRIILLLAMLLLAPQMAQAAEGYIDVTAPVSRKLKLFPAPATGLAGQVPPEVSRELSELFGMDLGLAGPFEVSGDGAGAD
LILKSSYSAQGGNITLECRLVDRVLNREITAKRYSGSAKELRRMGHAFSDEVLRAVTGEKGPFTGKIAYVTKASGNKEIF
VMDYDGHNPQRLTNNGSINLNPDFAPSGKEIIYTSYKKGNPDLYRRELFTGLEARISSRSGLNATGAYSPDGSKIAMVMS
KDGNSEIYLISREGKELARLTNNHAIDVSPAWSPDGSRIVFVSDRLGKPQVFIMNADGGNVHRLTANGAYNVTPRWSPKG
DRIVYARQGGGGFQIYAINADGTQDTQLTSAGSNEHPRFSPDGRFIVFSSTRDGAEAIYLMRADGSGQTRVSPNKSQNSH
PTWSVNW

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=294, Percent_Identity=30.2721088435374, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI32564215, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564217, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 44041; Mature: 44041

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILLLAMLLLAPQMAQAAEGYIDVTAPVSRKLKLFPAPATGLAGQVPPEVSRELSELF
CHHHHHHHHHHHCHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
GMDLGLAGPFEVSGDGAGADLILKSSYSAQGGNITLECRLVDRVLNREITAKRYSGSAKE
CCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCEEEEEEEHHHHHCCCCEEHHCCCCHHH
LRRMGHAFSDEVLRAVTGEKGPFTGKIAYVTKASGNKEIFVMDYDGHNPQRLTNNGSINL
HHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCEECCCCEEEE
NPDFAPSGKEIIYTSYKKGNPDLYRRELFTGLEARISSRSGLNATGAYSPDGSKIAMVMS
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
KDGNSEIYLISREGKELARLTNNHAIDVSPAWSPDGSRIVFVSDRLGKPQVFIMNADGGN
CCCCCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCC
VHRLTANGAYNVTPRWSPKGDRIVYARQGGGGFQIYAINADGTQDTQLTSAGSNEHPRFS
EEEEEECCEEECCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCEEECCCCCCCCCCC
PDGRFIVFSSTRDGAEAIYLMRADGSGQTRVSPNKSQNSHPTWSVNW
CCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCEEECC
>Mature Secondary Structure
MRIILLLAMLLLAPQMAQAAEGYIDVTAPVSRKLKLFPAPATGLAGQVPPEVSRELSELF
CHHHHHHHHHHHCHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
GMDLGLAGPFEVSGDGAGADLILKSSYSAQGGNITLECRLVDRVLNREITAKRYSGSAKE
CCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCEEEEEEEHHHHHCCCCEEHHCCCCHHH
LRRMGHAFSDEVLRAVTGEKGPFTGKIAYVTKASGNKEIFVMDYDGHNPQRLTNNGSINL
HHHHCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCEECCCCEEEE
NPDFAPSGKEIIYTSYKKGNPDLYRRELFTGLEARISSRSGLNATGAYSPDGSKIAMVMS
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
KDGNSEIYLISREGKELARLTNNHAIDVSPAWSPDGSRIVFVSDRLGKPQVFIMNADGGN
CCCCCEEEEEECCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCC
VHRLTANGAYNVTPRWSPKGDRIVYARQGGGGFQIYAINADGTQDTQLTSAGSNEHPRFS
EEEEEECCEEECCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCEEECCCCCCCCCCC
PDGRFIVFSSTRDGAEAIYLMRADGSGQTRVSPNKSQNSHPTWSVNW
CCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA