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The map label for this gene is fabZ [H]

Identifier: 197117234

GI number: 197117234

Start: 996416

End: 996850

Strand: Direct

Name: fabZ [H]

Synonym: Gbem_0842

Alternate gene names: 197117234

Gene position: 996416-996850 (Clockwise)

Preceding gene: 197117233

Following gene: 197117235

Centisome position: 21.59

GC content: 59.54

Gene sequence:

>435_bases
ATGCTTGATATAGTGCAGATTATGGAACTTCTTCCGCATCGCTACCCTTTCCTCCTGGTCGACAAGATCGTCGAGATGGA
GCCGGGAAAGCGGATCGTCGGCATCAAGAACGTCACCATGAACGAGCCGTTTTTCCAGGGGCACTTCCCCGGATTCCCGG
TCATGCCGGGGGTCCTGATCATCGAAGCGATGGCGCAGGTCGCCGCCATCCTGGCCTACAAGGCCGCGGAAGGCGACGCC
AAGGAGAAGGTCAGCTACTTCATGGCCATCGACAACGCCCGTTTCAGGAAACCGGTAAAGCCGGGCGACACCCTGAGAAT
CGAGGTGGAGACCCTGTTCTGCAAGCGCGGCATCTGGAGCGTAGCGGCCAAGGCCTACGTCGGCGAGACCCTGATGACCG
AAGCCGAGCTTAAGGCGACCCTCGGGAGCAAGTAA

Upstream 100 bases:

>100_bases
GGCGCTGGAGAAGCGGGTGGCGGAGTTGGAAGCGAAACTGGCCAAAGGGGAGTAATTACCTCGGCTCCCTCGGACGGAGC
CGGTTCAAGGAGAGATTTTA

Downstream 100 bases:

>100_bases
GCCCTCTTCAGCGGGGGATTCAGGAGAAAGAGATGATTCACAGCACCGCAATAATCCACCCCGGCGCCAAGATCGCCGAC
GGGGTCGAGATCGGCCCTTA

Product: (3R)-hydroxyacyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLDIVQIMELLPHRYPFLLVDKIVEMEPGKRIVGIKNVTMNEPFFQGHFPGFPVMPGVLIIEAMAQVAAILAYKAAEGDA
KEKVSYFMAIDNARFRKPVKPGDTLRIEVETLFCKRGIWSVAAKAYVGETLMTEAELKATLGSK

Sequences:

>Translated_144_residues
MLDIVQIMELLPHRYPFLLVDKIVEMEPGKRIVGIKNVTMNEPFFQGHFPGFPVMPGVLIIEAMAQVAAILAYKAAEGDA
KEKVSYFMAIDNARFRKPVKPGDTLRIEVETLFCKRGIWSVAAKAYVGETLMTEAELKATLGSK
>Mature_144_residues
MLDIVQIMELLPHRYPFLLVDKIVEMEPGKRIVGIKNVTMNEPFFQGHFPGFPVMPGVLIIEAMAQVAAILAYKAAEGDA
KEKVSYFMAIDNARFRKPVKPGDTLRIEVETLFCKRGIWSVAAKAYVGETLMTEAELKATLGSK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=48.5294117647059, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16058; Mature: 16058

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIVQIMELLPHRYPFLLVDKIVEMEPGKRIVGIKNVTMNEPFFQGHFPGFPVMPGVLI
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
IEAMAQVAAILAYKAAEGDAKEKVSYFMAIDNARFRKPVKPGDTLRIEVETLFCKRGIWS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHCCCCCCCCEEEEEHHHHHHHCCHHH
VAAKAYVGETLMTEAELKATLGSK
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDIVQIMELLPHRYPFLLVDKIVEMEPGKRIVGIKNVTMNEPFFQGHFPGFPVMPGVLI
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
IEAMAQVAAILAYKAAEGDAKEKVSYFMAIDNARFRKPVKPGDTLRIEVETLFCKRGIWS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHCCCCCCCCEEEEEHHHHHHHCCHHH
VAAKAYVGETLMTEAELKATLGSK
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA