Click here to switch to the map view.

The map label for this gene is yfbQ [C]

Identifier: 197117024

GI number: 197117024

Start: 747558

End: 748862

Strand: Reverse

Name: yfbQ [C]

Synonym: Gbem_0627

Alternate gene names: 197117024

Gene position: 748862-747558 (Counterclockwise)

Preceding gene: 197117025

Following gene: 197117023

Centisome position: 16.23

GC content: 62.3

Gene sequence:

>1305_bases
ATGCGCAACGAGATAGTCGCTCCCGGCGCGGGAGAACTTACCTACGAGATCAGGAACATCGTTACGGTTGCCGAGAAGGT
GCAACGCTTAGGGGTGAAGATCAACTGGGAGAACATAGGCGACCCCATCGTCAAGGGGGAGAACATCCCGCTCTGGATGA
AGGAGATCGTGGCGGCCGAGGCGATGAACGACGACAGCTACGCCTACTGCCCGACCCGCGGCGTCCTGGAGACCCGCGAG
TTCATCTGCGAGATCACCAACAAGCGCGGGGGCGCGCAGATCACCCCCGACGACATAATCTTCTTCAACGGCCTGGGCGA
CGCCATCGCCAAGGTGTACGGCAACCTGCGCCCCGAAAGCCGCGTGCTCATGCCCTCCCCCACCTACACCACCCACTCCA
TCGGCGAGGCGGCCCACGCGAACGCGGTGCCGGTCTGCTACCGCTTGAAGCCCGAGGACAACTGGTACCCGGACATGGAC
GACCTCGAGTGCCACGTGAAGTACAACCCGCAGATCGCCGGGATCATGATGATCAACCCGGACAACCCGACCGGGATGGT
GTACCCGGTGGAGGTGCTGAAGCAGATCGTCGAGATCGCGAGGAAATACGACCTCTTCATCATCGCCGACGAGGTGTACA
GCAACATCGTCTACAACGGCGAGAAGACGGTCCCCATCTCGGACGTAATCGGGCAGGTCCCCGCGATCGCAATGAAAGGG
ATCTCCAAGGAACTCCCGTGGCCCGGCTCCCGCTGCGGCTGGATCGAGGTGTACAACGCCGACCGCGACCCGCGCTTCAA
CAAGTTCGTCAACTCCATCCTCTCCTCCAAGATGAACGAGGTCTGCTCCACCACGCTGCCGCAGCGCTGCCTGCCGGCGG
TGATGAAGCACCCCGAGTACCACAACTACCTGAACGAGCGCATCACCCGCTACGAGAAGATGAGCAACATCACCTATGAG
GCGCTCTCGAAGGTGCCGGAGCTGGCCGTGAACCGCACCAACGGCGCCTTCTACATGGCGGTCCCCTTCAAGCCGGGGGT
CCTGAACAACACCCAGACCCTCCCCATCAAGAACCCGGAGATCCGGCAGTTGGTCGAGGGGATCGTGAACCAGCCGGGAG
TGGCGCCGGACAAGCGTTTCGTCTATTACATCCTGGCGCACACGGGGATCTGCGTGGTTCCCCTCTCCTCCTTCAACACG
GAGCTCCTCGGGTTCAGGGTAACCCTCCTGGAGCGGGACGAGGCGGAGTGCCGCAGGATCTACCGGACCCTCACCGAGAA
CATCGCCACCTACCTCGCCTCCTAG

Upstream 100 bases:

>100_bases
ACAAGAGATACTGAAGGCCGTGGGGGACCCCCGCGGCCTTTTTTTATACAAAATCCGGTTTTAGCTGCAATAAACGCATA
ACGTCCTAGGGGGAAAAAGA

Downstream 100 bases:

>100_bases
AGGAGATAAAAAAAGCCCCGCCGCAAGCGGGGCTTTTTCTTTGGCTAGAGCTGATTTATCTAAGGTCTTGAAATCCCCCC
TGTCCCCCAGCACTGCCCGG

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRNEIVAPGAGELTYEIRNIVTVAEKVQRLGVKINWENIGDPIVKGENIPLWMKEIVAAEAMNDDSYAYCPTRGVLETRE
FICEITNKRGGAQITPDDIIFFNGLGDAIAKVYGNLRPESRVLMPSPTYTTHSIGEAAHANAVPVCYRLKPEDNWYPDMD
DLECHVKYNPQIAGIMMINPDNPTGMVYPVEVLKQIVEIARKYDLFIIADEVYSNIVYNGEKTVPISDVIGQVPAIAMKG
ISKELPWPGSRCGWIEVYNADRDPRFNKFVNSILSSKMNEVCSTTLPQRCLPAVMKHPEYHNYLNERITRYEKMSNITYE
ALSKVPELAVNRTNGAFYMAVPFKPGVLNNTQTLPIKNPEIRQLVEGIVNQPGVAPDKRFVYYILAHTGICVVPLSSFNT
ELLGFRVTLLERDEAECRRIYRTLTENIATYLAS

Sequences:

>Translated_434_residues
MRNEIVAPGAGELTYEIRNIVTVAEKVQRLGVKINWENIGDPIVKGENIPLWMKEIVAAEAMNDDSYAYCPTRGVLETRE
FICEITNKRGGAQITPDDIIFFNGLGDAIAKVYGNLRPESRVLMPSPTYTTHSIGEAAHANAVPVCYRLKPEDNWYPDMD
DLECHVKYNPQIAGIMMINPDNPTGMVYPVEVLKQIVEIARKYDLFIIADEVYSNIVYNGEKTVPISDVIGQVPAIAMKG
ISKELPWPGSRCGWIEVYNADRDPRFNKFVNSILSSKMNEVCSTTLPQRCLPAVMKHPEYHNYLNERITRYEKMSNITYE
ALSKVPELAVNRTNGAFYMAVPFKPGVLNNTQTLPIKNPEIRQLVEGIVNQPGVAPDKRFVYYILAHTGICVVPLSSFNT
ELLGFRVTLLERDEAECRRIYRTLTENIATYLAS
>Mature_434_residues
MRNEIVAPGAGELTYEIRNIVTVAEKVQRLGVKINWENIGDPIVKGENIPLWMKEIVAAEAMNDDSYAYCPTRGVLETRE
FICEITNKRGGAQITPDDIIFFNGLGDAIAKVYGNLRPESRVLMPSPTYTTHSIGEAAHANAVPVCYRLKPEDNWYPDMD
DLECHVKYNPQIAGIMMINPDNPTGMVYPVEVLKQIVEIARKYDLFIIADEVYSNIVYNGEKTVPISDVIGQVPAIAMKG
ISKELPWPGSRCGWIEVYNADRDPRFNKFVNSILSSKMNEVCSTTLPQRCLPAVMKHPEYHNYLNERITRYEKMSNITYE
ALSKVPELAVNRTNGAFYMAVPFKPGVLNNTQTLPIKNPEIRQLVEGIVNQPGVAPDKRFVYYILAHTGICVVPLSSFNT
ELLGFRVTLLERDEAECRRIYRTLTENIATYLAS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=311, Percent_Identity=28.2958199356913, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4885351, Length=378, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI19263340, Length=374, Percent_Identity=25.9358288770053, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI215599424, Length=374, Percent_Identity=25.9358288770053, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1788627, Length=337, Percent_Identity=27.893175074184, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788722, Length=202, Percent_Identity=25.7425742574257, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=315, Percent_Identity=29.8412698412698, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=377, Percent_Identity=27.0557029177719, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=366, Percent_Identity=25.6830601092896, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859735, Length=338, Percent_Identity=27.2189349112426, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45551451, Length=373, Percent_Identity=25.4691689008043, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641770, Length=373, Percent_Identity=25.201072386059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641760, Length=373, Percent_Identity=25.201072386059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641768, Length=373, Percent_Identity=25.201072386059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641766, Length=373, Percent_Identity=25.201072386059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641764, Length=373, Percent_Identity=25.201072386059, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 48933; Mature: 48933

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNEIVAPGAGELTYEIRNIVTVAEKVQRLGVKINWENIGDPIVKGENIPLWMKEIVAAE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
AMNDDSYAYCPTRGVLETREFICEITNKRGGAQITPDDIIFFNGLGDAIAKVYGNLRPES
HCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHHHCCCCCCC
RVLMPSPTYTTHSIGEAAHANAVPVCYRLKPEDNWYPDMDDLECHVKYNPQIAGIMMINP
EEECCCCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEECC
DNPTGMVYPVEVLKQIVEIARKYDLFIIADEVYSNIVYNGEKTVPISDVIGQVPAIAMKG
CCCCCEEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHEECCCCCCCHHHHHHHHHHHHHHC
ISKELPWPGSRCGWIEVYNADRDPRFNKFVNSILSSKMNEVCSTTLPQRCLPAVMKHPEY
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
HNYLNERITRYEKMSNITYEALSKVPELAVNRTNGAFYMAVPFKPGVLNNTQTLPIKNPE
HHHHHHHHHHHHHHHCCHHHHHHCCHHHEEECCCCEEEEEECCCCCCCCCCEECCCCCHH
IRQLVEGIVNQPGVAPDKRFVYYILAHTGICVVPLSSFNTELLGFRVTLLERDEAECRRI
HHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEEEEEEECCCHHHHHHH
YRTLTENIATYLAS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRNEIVAPGAGELTYEIRNIVTVAEKVQRLGVKINWENIGDPIVKGENIPLWMKEIVAAE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
AMNDDSYAYCPTRGVLETREFICEITNKRGGAQITPDDIIFFNGLGDAIAKVYGNLRPES
HCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCEEEECCHHHHHHHHHCCCCCCC
RVLMPSPTYTTHSIGEAAHANAVPVCYRLKPEDNWYPDMDDLECHVKYNPQIAGIMMINP
EEECCCCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEECC
DNPTGMVYPVEVLKQIVEIARKYDLFIIADEVYSNIVYNGEKTVPISDVIGQVPAIAMKG
CCCCCEEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHEECCCCCCCHHHHHHHHHHHHHHC
ISKELPWPGSRCGWIEVYNADRDPRFNKFVNSILSSKMNEVCSTTLPQRCLPAVMKHPEY
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
HNYLNERITRYEKMSNITYEALSKVPELAVNRTNGAFYMAVPFKPGVLNNTQTLPIKNPE
HHHHHHHHHHHHHHHCCHHHHHHCCHHHEEECCCCEEEEEECCCCCCCCCCEECCCCCHH
IRQLVEGIVNQPGVAPDKRFVYYILAHTGICVVPLSSFNTELLGFRVTLLERDEAECRRI
HHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEEEEEEECCCHHHHHHH
YRTLTENIATYLAS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]