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The map label for this gene is ccmC [H]

Identifier: 194735071

GI number: 194735071

Start: 2357378

End: 2358124

Strand: Reverse

Name: ccmC [H]

Synonym: SeSA_A2478

Alternate gene names: 194735071

Gene position: 2358124-2357378 (Counterclockwise)

Preceding gene: 194734547

Following gene: 194734401

Centisome position: 50.08

GC content: 65.46

Gene sequence:

>747_bases
GTGACGACTATGTGGAAAACCCTTCATCAGCTGGCGGCGCCGCCCCGGCTGTATCAGATTTGCGGCAGGCTCGTGCCGTG
GCTGGCGGCGGCCGGCATCATCGCGCTGGCCACCGGCTGGGTTCGGGGCTTTGGTTTCGCCCCGGCGGACTACCAGCAGG
GGGAGGGCTACCGCATTATGTACCTGCATGTCCCGGCGGCCATCTGGTCAATGGGTATCTATGCGGCGATGGCGGTGGCG
GCGTTCACCGGGCTGGTCTGGCAGATGAAAATGGCCAGCCTTGCCGTCGCGGCGATGGCGCCGGTGGGGGCGGTGTACAC
CTTCATCGCGCTGGTCACCGGCGCGGCGTGGGGCAAACCGATGTGGGGCACCTGGTGGGTGTGGGACGCGCGCCTGACCT
CGGAGCTGGTGCTGCTGTTTCTCTACGCCGGGGTCATCGCCCTGTGGCACGCCTTTGACGACCGTAAAATGGCCGGGCGC
GCGGCGGGCATTCTGGTGCTGGTCGGCGTGGTGAACCTGCCGGTTATCCACTATTCCGTCGAGTGGTGGAACACCCTGCA
CCAGGGCTCGACGCAGATGCAGCAGAGTATCGACCCGGCGATGCGCTCGCCGCTGCGCTGGGCCATCGCCGGCTACCTGC
TGCTCTTTATGACGCTGGCGCTGATGCGGATGCGCAACCTGATTTTACTGATGGAAAAACGCCGCCCGTGGGTGAGCGAA
CTGATACTGAAAAGGGGGCACCGGTGA

Upstream 100 bases:

>100_bases
CAGCGCGACGTTAAGCCCGTTCGCCACCGCGGCGGCGCTGCGCCTCAGCGTGCAGTAGCGCCCCGGCGCGACGGACATTT
TACTGGTTTCAGGAGGTCAG

Downstream 100 bases:

>100_bases
GTCCGGCATTTTCATCGTGGAGCGATTTTTTCGCCATGGGCGGGTACGCCTTTTTTGTCTGGCTGGCGGTGGCGATGACC
GTGGCGCCGCTGGCGCTGCT

Product: ABC superfamily protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTTMWKTLHQLAAPPRLYQICGRLVPWLAAAGIIALATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVA
AFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGR
AAGILVLVGVVNLPVIHYSVEWWNTLHQGSTQMQQSIDPAMRSPLRWAIAGYLLLFMTLALMRMRNLILLMEKRRPWVSE
LILKRGHR

Sequences:

>Translated_248_residues
MTTMWKTLHQLAAPPRLYQICGRLVPWLAAAGIIALATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVA
AFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGR
AAGILVLVGVVNLPVIHYSVEWWNTLHQGSTQMQQSIDPAMRSPLRWAIAGYLLLFMTLALMRMRNLILLMEKRRPWVSE
LILKRGHR
>Mature_247_residues
TTMWKTLHQLAAPPRLYQICGRLVPWLAAAGIIALATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVAA
FTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRA
AGILVLVGVVNLPVIHYSVEWWNTLHQGSTQMQQSIDPAMRSPLRWAIAGYLLLFMTLALMRMRNLILLMEKRRPWVSEL
ILKRGHR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=245, Percent_Identity=85.3061224489796, Blast_Score=433, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27818; Mature: 27686

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCC
>Mature Secondary Structure 
TTMWKTLHQLAAPPRLYQICGRLVPWLAAAGIIALATGWVRGFGFAPADYQQGEGYRIM
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
YLHVPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAGILVLVGVVNLPVIHYSV
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEEH
EWWNTLHQGSTQMQQSIDPAMRSPLRWAIAGYLLLFMTLALMRMRNLILLMEKRRPWVSE
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LILKRGHR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]