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The map label for this gene is ccmB [H]

Identifier: 194734547

GI number: 194734547

Start: 2358167

End: 2358823

Strand: Reverse

Name: ccmB [H]

Synonym: SeSA_A2479

Alternate gene names: 194734547

Gene position: 2358823-2358167 (Counterclockwise)

Preceding gene: 194734093

Following gene: 194735071

Centisome position: 50.09

GC content: 70.32

Gene sequence:

>657_bases
ATGTGGCGTGTCTTCTGTCTCGAACTGCGCGTGGCGTTCCGCCACGGCGCGGACATCGCCGGCCCGCTGTGGTTCTTCCT
GATGGTCATCACCCTGTTTCCGTTAAGCGTCGGGCCGCAGCCGCAGCTGCTGGCGCGTATCGCGCCGGGCATCATCCAGG
TGGCGGCGCTGCTGGCCTCGCTGCTGGCGCTGGAGCGGCTGTTTCGCGACGACCTGCAGGACGGCAGCCTGGAGCAGCTG
ATGCTGCTGCCGGTGCCGCTGCCGGCGGTGGTGCTGGCGAAGGTGCTGGCCCACTGGGCGGTGACCGGCCTGCCGCTGAT
TATGCTCTCCCCGCTGGTGGCGCTGCTGCTGGGGATGGACGTGTACGGCTGGAAAATCATGGCGCTGACGCTGCTGCTCG
GCACGCCGGCGCTGGGGTTTCTCGCCGCGCCGGGCGTCGGGCTGACGGCCGGCCTGCGGCGCGGCGGCGTCCTGCTGGGC
ATTCTGGTGCTGCCGCTGAGTGTCCCGGTGCTGATTTTCGCCGCCGCGGCGATGGACGCGGCATCAATGCATTTACCCGC
TGACGGCTATCTGGCGGTGCTGGGGGCGCTGCTGGCGGGCAGCGCGACGTTAAGCCCGTTCGCCACCGCGGCGGCGCTGC
GCCTCAGCGTGCAGTAG

Upstream 100 bases:

>100_bases
CGCAGGGCGGGATGGTCATTCTCACCACCCACCAGCCGTTGCCGGGGGCCGCGGACACCGTCCGCCGCCTGGCGCTGACC
GGCGGGGAGGCTGGGCTGTG

Downstream 100 bases:

>100_bases
CGCCCCGGCGCGACGGACATTTTACTGGTTTCAGGAGGTCAGGTGACGACTATGTGGAAAACCCTTCATCAGCTGGCGGC
GCCGCCCCGGCTGTATCAGA

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQLLARIAPGIIQVAALLASLLALERLFRDDLQDGSLEQL
MLLPVPLPAVVLAKVLAHWAVTGLPLIMLSPLVALLLGMDVYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLLG
ILVLPLSVPVLIFAAAAMDAASMHLPADGYLAVLGALLAGSATLSPFATAAALRLSVQ

Sequences:

>Translated_218_residues
MWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQLLARIAPGIIQVAALLASLLALERLFRDDLQDGSLEQL
MLLPVPLPAVVLAKVLAHWAVTGLPLIMLSPLVALLLGMDVYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLLG
ILVLPLSVPVLIFAAAAMDAASMHLPADGYLAVLGALLAGSATLSPFATAAALRLSVQ
>Mature_218_residues
MWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQLLARIAPGIIQVAALLASLLALERLFRDDLQDGSLEQL
MLLPVPLPAVVLAKVLAHWAVTGLPLIMLSPLVALLLGMDVYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLLG
ILVLPLSVPVLIFAAAAMDAASMHLPADGYLAVLGALLAGSATLSPFATAAALRLSVQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=217, Percent_Identity=84.7926267281106, Blast_Score=301, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22821; Mature: 22821

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQLLARIAPGIIQVAALLAS
CCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LLALERLFRDDLQDGSLEQLMLLPVPLPAVVLAKVLAHWAVTGLPLIMLSPLVALLLGMD
HHHHHHHHHHCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLLGILVLPLSVPVLIFAAAAMDA
HHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ASMHLPADGYLAVLGALLAGSATLSPFATAAALRLSVQ
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHEECC
>Mature Secondary Structure
MWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQLLARIAPGIIQVAALLAS
CCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LLALERLFRDDLQDGSLEQLMLLPVPLPAVVLAKVLAHWAVTGLPLIMLSPLVALLLGMD
HHHHHHHHHHCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLLGILVLPLSVPVLIFAAAAMDA
HHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ASMHLPADGYLAVLGALLAGSATLSPFATAAALRLSVQ
HHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]