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The map label for this gene is sirB2 [H]

Identifier: 194734672

GI number: 194734672

Start: 1848137

End: 1848514

Strand: Reverse

Name: sirB2 [H]

Synonym: SeSA_A1911

Alternate gene names: 194734672

Gene position: 1848514-1848137 (Counterclockwise)

Preceding gene: 194735200

Following gene: 194734431

Centisome position: 39.25

GC content: 51.59

Gene sequence:

>378_bases
ATGTTGCTCACGCTTCATCTTATCTGTGTTGCGCTCTCCGTCAGTTTGTTTGTCGCTCGTTACTGGTGGCGCTATTGCGG
CCATGCGTTGGCCGCCGCGCGCTGGACACGAATCGTGCCTCCCGTCATAGATACCCTGTTACTGCTTAGCGGTATCGGGT
TAATCGTTAAAACGCACATCCTGCCATTCACGGAGTCGGGCTCATGGCTGACTGAAAAACTGTTTGGCGTTATCATCTAC
ATCGTTTTGGGTTTTATTGCGCTTGATTATCGTCAGGCGCGCAGCCAGCAGGTGCGTTTTATCGCTTTTCCGCTGGCGCT
GGTGGTGCTGTACATCATCATTAAACTCGCCACCACAAAAATACCGTTACTGGGGTAA

Upstream 100 bases:

>100_bases
CGGTTTTCAGGCGGTCTGGTTACTCGGATGTAGAAACGTGTCGTGATTATGGTGGTAATGAACGCGTGACCTGCGGACGT
TTTACGCCATGACAACTGCA

Downstream 100 bases:

>100_bases
GTCATGAGGTCGTTAGCTGATTTCGAATTTAACAATGCGCCGCTGTGTGATGGCATGATCCTGGCATCAGAGATGATTCG
CCTGGATTTTCCCACGCAGT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIVKTHILPFTESGSWLTEKLFGVIIY
IVLGFIALDYRQARSQQVRFIAFPLALVVLYIIIKLATTKIPLLG

Sequences:

>Translated_125_residues
MLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIVKTHILPFTESGSWLTEKLFGVIIY
IVLGFIALDYRQARSQQVRFIAFPLALVVLYIIIKLATTKIPLLG
>Mature_125_residues
MLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIVKTHILPFTESGSWLTEKLFGVIIY
IVLGFIALDYRQARSQQVRFIAFPLALVVLYIIIKLATTKIPLLG

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC [H]

COG id: COG3094

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787464, Length=124, Percent_Identity=75, Blast_Score=184, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007360 [H]

Pfam domain/function: PF04247 SirB [H]

EC number: NA

Molecular weight: Translated: 14078; Mature: 14078

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIVKTHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LPFTESGSWLTEKLFGVIIYIVLGFIALDYRQARSQQVRFIAFPLALVVLYIIIKLATTK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPLLG
CCCCC
>Mature Secondary Structure
MLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIVKTHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LPFTESGSWLTEKLFGVIIYIVLGFIALDYRQARSQQVRFIAFPLALVVLYIIIKLATTK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPLLG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]