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The map label for this gene is sirB1 [H]

Identifier: 194734431

GI number: 194734431

Start: 1847324

End: 1848133

Strand: Reverse

Name: sirB1 [H]

Synonym: SeSA_A1910

Alternate gene names: 194734431

Gene position: 1848133-1847324 (Counterclockwise)

Preceding gene: 194734672

Following gene: 194737901

Centisome position: 39.25

GC content: 49.14

Gene sequence:

>810_bases
ATGAGGTCGTTAGCTGATTTCGAATTTAACAATGCGCCGCTGTGTGATGGCATGATCCTGGCATCAGAGATGATTCGCCT
GGATTTTCCCACGCAGTTTGTCTACGACGAACTGGAACGTCTGGTCAGTCTGGCGCAGGAAGAAATTAGCCAGCTCCTGT
CTCAGGATGAGCAACTGGAAAAATTGCTGGCACTTTTTTACGGCGAGTGGGGGTTCACGGATTCCCGTGGCGTTTACCGT
CTTTCTGATGCTTTATGGCTCGATAAAGTCCTGAAAAAACGCCAGGGGAGCGCGGTATCGTTGGGCGCTATTTTATTATG
GGTAGCAAACCGTCTTGATTTGCCGTTGGTGCCCGTTATCTTCCCAACGCAGTTGATTTTGCGTATTGAATCGCTGGAAG
GGGAAATGTGGCTGATTAACCCGTTCAACGGTGAAACGCTTGATGAACATACTCTGGAAGTCTGGTTAAAAGGCAATATT
AGTCCGGTCGCCGAGTTGTTTAACGAAGATTTGGACGAGGCGGATAACGCCGAAGTGATTCGTAAGCTACTGGATACGCT
GAAATCCTCGCTGATGGAGGAACGGCAAATGGAGCTGGCGCTGCGCGTTAGCGAAGCATTGTTGCAATTTAACCCGGAAG
ATCCTTACGAAATCCGTGACCGCGGGTTGATCTACGCGCAGCTTGAGTGTGAACACGTTGCGCTGACTGATTTAAGCTAC
TTCGTTGAACAGTGTCCGGAAGACCCGATCAGCGAAATGATTCGTGCGCAGATCAACACCATTGCGCACAAGCAAATTGT
TCTACATTAA

Upstream 100 bases:

>100_bases
CAGCCAGCAGGTGCGTTTTATCGCTTTTCCGCTGGCGCTGGTGGTGCTGTACATCATCATTAAACTCGCCACCACAAAAA
TACCGTTACTGGGGTAAGTC

Downstream 100 bases:

>100_bases
TTAACCGACATTTTACCTATAAGTGTAAGGCGATCCTATGAAACAAAAAGTGGTTAACATTGGCGACATTAAGGTGGCAA
ATGACCTGCCGTTTGTGCTG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWVANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH

Sequences:

>Translated_269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWVANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH
>Mature_269_residues
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYR
LSDALWLDKVLKKRQGSAVSLGAILLWVANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
FVEQCPEDPISEMIRAQINTIAHKQIVLH

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC [H]

COG id: COG2912

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0162 family [H]

Homologues:

Organism=Escherichia coli, GI1787465, Length=269, Percent_Identity=86.2453531598513, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30911; Mature: 30911

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLE
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLGAILLWVANRLDLPLVPVI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
FPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNISPVAELFNEDLDEADNAEVI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHH
RKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCHHHHHHHHH
FVEQCPEDPISEMIRAQINTIAHKQIVLH
HHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLE
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLGAILLWVANRLDLPLVPVI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
FPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNISPVAELFNEDLDEADNAEVI
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCHHHH
RKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCHHHHHHHHH
FVEQCPEDPISEMIRAQINTIAHKQIVLH
HHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]