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The map label for this gene is dsbD [H]

Identifier: 194334642

GI number: 194334642

Start: 2015685

End: 2017826

Strand: Reverse

Name: dsbD [H]

Synonym: Paes_1843

Alternate gene names: 194334642

Gene position: 2017826-2015685 (Counterclockwise)

Preceding gene: 194334643

Following gene: 194334638

Centisome position: 80.3

GC content: 54.06

Gene sequence:

>2142_bases
ATGCGACTACGCCGGATTTTTTCATTGATCATACTGCTGAACCTTGCTGTTCATGCCTCCCTGACTGCTGCAATGGCCTT
TGTCTTCATGGAGGATACAGCAGAGCCAGTCAAGGCAGAACTCTTTGCAGCCGGAGAGCTTGATGATGGAGGTCTTCTTG
TTGCCGTTCATCTTACCATTCAGCCAGGCTGGCATCTCTACTGGGAGCATCCCGGTGAGGCGGGCATGCCGGTCAGCATC
ACATGGAGGCTTCCCGAAGGCTACCGTGCTCTTCCCCTTGAATTTCCTCTTCCCGGCCGATTTGAGGCGGCCGGTCTTAT
CGGCTATGGATACGATGAAGAAGTTGTGCTTTTTTCAGCCATTGTCCCGCAGGTTCCCGGCAACAGCCAACGGCTTCGGT
CAGACCTTTTTCCGCTTCAGGCAGAAGTGAGCTGGCTTTCATGCAGGGAAAGCTGTATCCCCGGATCCGCATCGCTTCGT
CTCGAAACCGGAGAGCCGGATTCCTCGCGTTCAGGGCTGGTCGATCTGTGGCGTTCGAAAGTTCCCGTTGCGTCCAGCTC
CGCCACCGTTGCTGTCGAGCGGTTTGTTCTCGAAGAGGTGAATGGCGATTTCAGGCTTCGTGCTGATCTTGCAGGTCCGG
ATGCAGATGCGATCAACGGTTTTTTTCCCCTCTCTCCACTTGAGGGTCTTGATCTCAAAGGGATCGAAGCTGCTCCGGGG
CGACTGTTTCTTCCTTTGAAGGGGGCTGATTTTCCTGAAACCGTATCCGGGGTTCTGGTTACTGGGAACGGTGCCTATCG
TACGGAGAAGATTCCGGTCGAGATCTCTTCCGGCAGTTCCGCTCCGGATGATGCGGGCTCTCTTGGAGCGATGCTTTTCC
TCGCCTTTTTTGGCGGCATGCTGCTCAATATTATGCCCTGTGTACTGCCTGTTCTCGGTCTCAAGGTCTTCAGCCTGATC
GGGCCGGGTGGAGATCGTGCTGCAGGACGTTTCCTGAGCCTTGTTTTTGCCGGAGGAGTGCTTTTTTCTTTCTGGGTTCT
CGCAGCATTTATCTGGGGTTTGCAGGCAATGGGCGCCCAGGTTGGCTGGGGATTTCAGTTTCAGTCTCCGGCTTTCGTCA
TGTTTATGGCTGCTGTAGTGTTTGCATTCGCTCTCAACCTGTTTGGTGTTTTTGAGTTCAGCGCTCCGGTTGTTTCAGGA
CGGCTTGGACGGCTCGCTTCCCATCATGACAGTGCGGGTGCTTTTGTCAGCGGGGTTCTTGCCACGACACTGGCGACACC
CTGTACAGCGCCTTTTCTTGGAACAGCCCTTGGTTTTGCTTTTGCACAGCCACCCGGTATCATTTTTCTCATTTTTACGG
TTATCGCTGCGGGTATGGCGATGCCGTATGTTGTTCTGGCATGGCATCCTTCATGGTTGAAGTTTCTTCCGAGGCCAGGC
CAATGGATGTATCGCTTCAAACAGATCATGGGTTTCATTCTCGTTGCTGTTGTCGTCTGGCTCGCCTCAATATTGGGCAG
TCAGGGGGGGAGCCCGGCTATGCTGAACCTGTTTGTGCTCCTTTTTGCTGTCTCATTTGTTCTCTGGCTTACCGGTCTTT
TTACTGCTCCCGGTACGTCGACGCTTCGTCAGGCGCTCGTCTGGCTGATCACGATAGGCTTTCTCGCCGGGGCTTATATG
CTTCTTTCCGGAAGGATCGGAACGATATCGTCTGACTCCCGCAACAGTCTGGAACCCGGCAGCCATACCGATGGTAACGG
CGTCGTCTGGCTTGACTACAGCCCGGATGTTCTTGATACTCTCCTGAAGGAAGAAAAGAGCGTCCTGATCGATTTTACCG
CAGAGTGGTGTTTGACCTGTAAGGTGCTGGAAGCAAGTGTTCTCGGCAATGAAGAGATTGGACGTGCGCTGAAGCGTGAG
GGGCTTGTCGCGGTCAGGGCTGACTGGACAAGTCGAAATGATGAAATTACCGCTCTTCTCCAGCGTTTTGGCCGTTCCGG
CATCCCTCTTCTTGTCATTATTCCTCAGGGGCGGATAGACAATGCTGTGGTGCTGCCTGAAGTCGTTACCGTCGATATGC
TTCTCGACGCGCTCTCCGGGGTTTCCGGCGATTCGCTTTCAAAGCTCCAGGGCAATATGTGA

Upstream 100 bases:

>100_bases
CTTCCATCAGCGCAGAACAGCGTGCACAGTTATCAGTCTGTGTAAGTTCTGTTATGGTATCCATGAATGTTCAACCCCGG
TCACGGGGAAAGTGTTGATT

Downstream 100 bases:

>100_bases
CTCGGTGGAGTGTGCTCTGAGGACCATAGCCAGCTCATCAATGAGCCCTGGGCCGTATTTGTTCAGATAGTAAAAGATAT
TGACGACTCTTTCCTGAGGT

Product: thiol-disulfide interchange protein DsbD precursor-like protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MRLRRIFSLIILLNLAVHASLTAAMAFVFMEDTAEPVKAELFAAGELDDGGLLVAVHLTIQPGWHLYWEHPGEAGMPVSI
TWRLPEGYRALPLEFPLPGRFEAAGLIGYGYDEEVVLFSAIVPQVPGNSQRLRSDLFPLQAEVSWLSCRESCIPGSASLR
LETGEPDSSRSGLVDLWRSKVPVASSSATVAVERFVLEEVNGDFRLRADLAGPDADAINGFFPLSPLEGLDLKGIEAAPG
RLFLPLKGADFPETVSGVLVTGNGAYRTEKIPVEISSGSSAPDDAGSLGAMLFLAFFGGMLLNIMPCVLPVLGLKVFSLI
GPGGDRAAGRFLSLVFAGGVLFSFWVLAAFIWGLQAMGAQVGWGFQFQSPAFVMFMAAVVFAFALNLFGVFEFSAPVVSG
RLGRLASHHDSAGAFVSGVLATTLATPCTAPFLGTALGFAFAQPPGIIFLIFTVIAAGMAMPYVVLAWHPSWLKFLPRPG
QWMYRFKQIMGFILVAVVVWLASILGSQGGSPAMLNLFVLLFAVSFVLWLTGLFTAPGTSTLRQALVWLITIGFLAGAYM
LLSGRIGTISSDSRNSLEPGSHTDGNGVVWLDYSPDVLDTLLKEEKSVLIDFTAEWCLTCKVLEASVLGNEEIGRALKRE
GLVAVRADWTSRNDEITALLQRFGRSGIPLLVIIPQGRIDNAVVLPEVVTVDMLLDALSGVSGDSLSKLQGNM

Sequences:

>Translated_713_residues
MRLRRIFSLIILLNLAVHASLTAAMAFVFMEDTAEPVKAELFAAGELDDGGLLVAVHLTIQPGWHLYWEHPGEAGMPVSI
TWRLPEGYRALPLEFPLPGRFEAAGLIGYGYDEEVVLFSAIVPQVPGNSQRLRSDLFPLQAEVSWLSCRESCIPGSASLR
LETGEPDSSRSGLVDLWRSKVPVASSSATVAVERFVLEEVNGDFRLRADLAGPDADAINGFFPLSPLEGLDLKGIEAAPG
RLFLPLKGADFPETVSGVLVTGNGAYRTEKIPVEISSGSSAPDDAGSLGAMLFLAFFGGMLLNIMPCVLPVLGLKVFSLI
GPGGDRAAGRFLSLVFAGGVLFSFWVLAAFIWGLQAMGAQVGWGFQFQSPAFVMFMAAVVFAFALNLFGVFEFSAPVVSG
RLGRLASHHDSAGAFVSGVLATTLATPCTAPFLGTALGFAFAQPPGIIFLIFTVIAAGMAMPYVVLAWHPSWLKFLPRPG
QWMYRFKQIMGFILVAVVVWLASILGSQGGSPAMLNLFVLLFAVSFVLWLTGLFTAPGTSTLRQALVWLITIGFLAGAYM
LLSGRIGTISSDSRNSLEPGSHTDGNGVVWLDYSPDVLDTLLKEEKSVLIDFTAEWCLTCKVLEASVLGNEEIGRALKRE
GLVAVRADWTSRNDEITALLQRFGRSGIPLLVIIPQGRIDNAVVLPEVVTVDMLLDALSGVSGDSLSKLQGNM
>Mature_713_residues
MRLRRIFSLIILLNLAVHASLTAAMAFVFMEDTAEPVKAELFAAGELDDGGLLVAVHLTIQPGWHLYWEHPGEAGMPVSI
TWRLPEGYRALPLEFPLPGRFEAAGLIGYGYDEEVVLFSAIVPQVPGNSQRLRSDLFPLQAEVSWLSCRESCIPGSASLR
LETGEPDSSRSGLVDLWRSKVPVASSSATVAVERFVLEEVNGDFRLRADLAGPDADAINGFFPLSPLEGLDLKGIEAAPG
RLFLPLKGADFPETVSGVLVTGNGAYRTEKIPVEISSGSSAPDDAGSLGAMLFLAFFGGMLLNIMPCVLPVLGLKVFSLI
GPGGDRAAGRFLSLVFAGGVLFSFWVLAAFIWGLQAMGAQVGWGFQFQSPAFVMFMAAVVFAFALNLFGVFEFSAPVVSG
RLGRLASHHDSAGAFVSGVLATTLATPCTAPFLGTALGFAFAQPPGIIFLIFTVIAAGMAMPYVVLAWHPSWLKFLPRPG
QWMYRFKQIMGFILVAVVVWLASILGSQGGSPAMLNLFVLLFAVSFVLWLTGLFTAPGTSTLRQALVWLITIGFLAGAYM
LLSGRIGTISSDSRNSLEPGSHTDGNGVVWLDYSPDVLDTLLKEEKSVLIDFTAEWCLTCKVLEASVLGNEEIGRALKRE
GLVAVRADWTSRNDEITALLQRFGRSGIPLLVIIPQGRIDNAVVLPEVVTVDMLLDALSGVSGDSLSKLQGNM

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=451, Percent_Identity=23.5033259423503, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 76410; Mature: 76410

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRRIFSLIILLNLAVHASLTAAMAFVFMEDTAEPVKAELFAAGELDDGGLLVAVHLTI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCEEEEEEEEE
QPGWHLYWEHPGEAGMPVSITWRLPEGYRALPLEFPLPGRFEAAGLIGYGYDEEVVLFSA
CCCEEEEEECCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCCCEEEEEH
IVPQVPGNSQRLRSDLFPLQAEVSWLSCRESCIPGSASLRLETGEPDSSRSGLVDLWRSK
HHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHCC
VPVASSSATVAVERFVLEEVNGDFRLRADLAGPDADAINGFFPLSPLEGLDLKGIEAAPG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCC
RLFLPLKGADFPETVSGVLVTGNGAYRTEKIPVEISSGSSAPDDAGSLGAMLFLAFFGGM
EEEEEECCCCCCCCCCCEEEECCCCEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LLNIMPCVLPVLGLKVFSLIGPGGDRAAGRFLSLVFAGGVLFSFWVLAAFIWGLQAMGAQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGWGFQFQSPAFVMFMAAVVFAFALNLFGVFEFSAPVVSGRLGRLASHHDSAGAFVSGVL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHH
ATTLATPCTAPFLGTALGFAFAQPPGIIFLIFTVIAAGMAMPYVVLAWHPSWLKFLPRPG
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCCC
QWMYRFKQIMGFILVAVVVWLASILGSQGGSPAMLNLFVLLFAVSFVLWLTGLFTAPGTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TLRQALVWLITIGFLAGAYMLLSGRIGTISSDSRNSLEPGSHTDGNGVVWLDYSPDVLDT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
LLKEEKSVLIDFTAEWCLTCKVLEASVLGNEEIGRALKREGLVAVRADWTSRNDEITALL
HHHCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
QRFGRSGIPLLVIIPQGRIDNAVVLPEVVTVDMLLDALSGVSGDSLSKLQGNM
HHHCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MRLRRIFSLIILLNLAVHASLTAAMAFVFMEDTAEPVKAELFAAGELDDGGLLVAVHLTI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCEEEEEEEEE
QPGWHLYWEHPGEAGMPVSITWRLPEGYRALPLEFPLPGRFEAAGLIGYGYDEEVVLFSA
CCCEEEEEECCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCCCEEEEEH
IVPQVPGNSQRLRSDLFPLQAEVSWLSCRESCIPGSASLRLETGEPDSSRSGLVDLWRSK
HHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHCC
VPVASSSATVAVERFVLEEVNGDFRLRADLAGPDADAINGFFPLSPLEGLDLKGIEAAPG
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCC
RLFLPLKGADFPETVSGVLVTGNGAYRTEKIPVEISSGSSAPDDAGSLGAMLFLAFFGGM
EEEEEECCCCCCCCCCCEEEECCCCEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LLNIMPCVLPVLGLKVFSLIGPGGDRAAGRFLSLVFAGGVLFSFWVLAAFIWGLQAMGAQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGWGFQFQSPAFVMFMAAVVFAFALNLFGVFEFSAPVVSGRLGRLASHHDSAGAFVSGVL
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHH
ATTLATPCTAPFLGTALGFAFAQPPGIIFLIFTVIAAGMAMPYVVLAWHPSWLKFLPRPG
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHCCCCC
QWMYRFKQIMGFILVAVVVWLASILGSQGGSPAMLNLFVLLFAVSFVLWLTGLFTAPGTS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TLRQALVWLITIGFLAGAYMLLSGRIGTISSDSRNSLEPGSHTDGNGVVWLDYSPDVLDT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
LLKEEKSVLIDFTAEWCLTCKVLEASVLGNEEIGRALKREGLVAVRADWTSRNDEITALL
HHHCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
QRFGRSGIPLLVIIPQGRIDNAVVLPEVVTVDMLLDALSGVSGDSLSKLQGNM
HHHCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA