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The map label for this gene is accD

Identifier: 194334638

GI number: 194334638

Start: 2009464

End: 2010303

Strand: Reverse

Name: accD

Synonym: Paes_1839

Alternate gene names: 194334638

Gene position: 2010303-2009464 (Counterclockwise)

Preceding gene: 194334642

Following gene: 194334636

Centisome position: 80.0

GC content: 49.76

Gene sequence:

>840_bases
ATGGTCTGGTTTAAACGCGCAAAGCCTTCGATTTTTACGAAAGATAAACGGGATATGCCTGAGGGGCTGTGGTGGAAATG
TGAAAGCTGCGGCGCAATGCTGCATAAAAAACAGGTTGAAGACCATTTCTACACCTGTTGTGAGTGCGGCTACCATTTCA
GACTTTCCCCCTATCAGTACTTTTCTCTGCTTTTCGATGAAAAGAAATATGACGAGTTCGATGACAATCTGCGCGCAGCC
GATCCGCTGCATTTTTCCGACACAAGGAAATATCCGGACCGTGTTCACGATATTCTCGAAAAAACGGGAAAAACGGAAGC
ATGCCGAAACGCCATCGGAAGAGTCAGCGGTCATGATCTGGTGATTTCAGCTATGGATTTCGGGTTCATTGGAGGCTCGA
TGGGCTCGGTGGTAGGGGAGAAAATCTCCCGTGCCGTCTCAAAGAGCATTGAGCACAATGCTCCGCTTCTGATCATATCA
CAGTCCGGCGGGGCCAGGATGATGGAGGGTGCCTTCAGTCTTATGCAGATGGCAAAGACCTCAGCCAGGCTTTCGCAGCT
CAGTGCCAGAGGGATTCCATATATATCGCTCATGACCAACCCGACAATGGGGGGGACAAGCGCTTCCTATGCCATGCTTG
GAGATATTAATATCAGTGAGCCGAAAGCACTGATAGGGTTTGCCGGACCAAGGGTTATCCGCGATACCATCAAGCGGGAC
CTTCCTGAAGGCTTTCAGCGGGCGGAATTTCTTTTAGAGCACGGATTTCTGGATTGTATCGTCCATCGCAGAGATCTGAA
ACACCGTCTTTCACAGATCCTCGGTCATCTTTCTTCCTGA

Upstream 100 bases:

>100_bases
TGATCGTAGCAATGGTTGATTCCCGGGAGTTGTTTTGAGTTCTCAGGGTGTCTTTATATCTTCAGGTTTAAATGTAATCA
TCTTTAGTCATATTTGTATC

Downstream 100 bases:

>100_bases
GTGTTCCATCCAAGCGCTGAGGCAGTGACCGGAAACTGTTCCATGAAAATTGTCCTTACCGCTTCAGCGATCTCCCGGTG
CTCTTTCTGCGTGCCGGGAT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MVWFKRAKPSIFTKDKRDMPEGLWWKCESCGAMLHKKQVEDHFYTCCECGYHFRLSPYQYFSLLFDEKKYDEFDDNLRAA
DPLHFSDTRKYPDRVHDILEKTGKTEACRNAIGRVSGHDLVISAMDFGFIGGSMGSVVGEKISRAVSKSIEHNAPLLIIS
QSGGARMMEGAFSLMQMAKTSARLSQLSARGIPYISLMTNPTMGGTSASYAMLGDINISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDCIVHRRDLKHRLSQILGHLSS

Sequences:

>Translated_279_residues
MVWFKRAKPSIFTKDKRDMPEGLWWKCESCGAMLHKKQVEDHFYTCCECGYHFRLSPYQYFSLLFDEKKYDEFDDNLRAA
DPLHFSDTRKYPDRVHDILEKTGKTEACRNAIGRVSGHDLVISAMDFGFIGGSMGSVVGEKISRAVSKSIEHNAPLLIIS
QSGGARMMEGAFSLMQMAKTSARLSQLSARGIPYISLMTNPTMGGTSASYAMLGDINISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDCIVHRRDLKHRLSQILGHLSS
>Mature_279_residues
MVWFKRAKPSIFTKDKRDMPEGLWWKCESCGAMLHKKQVEDHFYTCCECGYHFRLSPYQYFSLLFDEKKYDEFDDNLRAA
DPLHFSDTRKYPDRVHDILEKTGKTEACRNAIGRVSGHDLVISAMDFGFIGGSMGSVVGEKISRAVSKSIEHNAPLLIIS
QSGGARMMEGAFSLMQMAKTSARLSQLSARGIPYISLMTNPTMGGTSASYAMLGDINISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFLDCIVHRRDLKHRLSQILGHLSS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=48.3754512635379, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_PROA2 (B4S459)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016498.1
- ProteinModelPortal:   B4S459
- SMR:   B4S459
- GeneID:   6460219
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1839
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK637819
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31422; Mature: 31422

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWFKRAKPSIFTKDKRDMPEGLWWKCESCGAMLHKKQVEDHFYTCCECGYHFRLSPYQY
CCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHH
FSLLFDEKKYDEFDDNLRAADPLHFSDTRKYPDRVHDILEKTGKTEACRNAIGRVSGHDL
HHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
VISAMDFGFIGGSMGSVVGEKISRAVSKSIEHNAPLLIISQSGGARMMEGAFSLMQMAKT
EEEEHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SARLSQLSARGIPYISLMTNPTMGGTSASYAMLGDINISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFLDCIVHRRDLKHRLSQILGHLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVWFKRAKPSIFTKDKRDMPEGLWWKCESCGAMLHKKQVEDHFYTCCECGYHFRLSPYQY
CCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHH
FSLLFDEKKYDEFDDNLRAADPLHFSDTRKYPDRVHDILEKTGKTEACRNAIGRVSGHDL
HHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
VISAMDFGFIGGSMGSVVGEKISRAVSKSIEHNAPLLIISQSGGARMMEGAFSLMQMAKT
EEEEHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SARLSQLSARGIPYISLMTNPTMGGTSASYAMLGDINISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFLDCIVHRRDLKHRLSQILGHLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA