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The map label for this gene is dnaC [H]

Identifier: 194333182

GI number: 194333182

Start: 368312

End: 369862

Strand: Reverse

Name: dnaC [H]

Synonym: Paes_0338

Alternate gene names: 194333182

Gene position: 369862-368312 (Counterclockwise)

Preceding gene: 194333183

Following gene: 194333181

Centisome position: 14.72

GC content: 50.35

Gene sequence:

>1551_bases
ATGAAAGGAACTATCGCCAGAAAAGGCAATGGAGGAATCGATCTGGGCAAGGATATCGATTTTTCCCAGGAAAGCAGAAT
CCCTCCATACTCCATCGAAGTAGAGCAGGAGGTGCTTGCCTGTATCCTCCTTGAAGGCGAACCGATTGAGCAGGTCATAC
AGATCTTCGGAGATAACGATGAAAAAGTCTTTTACGAACAGCGCCACCAGCTTATCTACAAGGCAATGCTGGAACTCTAC
CAGAAACGTCTTGCCATCGACCTCATTACCGTAGGTGAAGAACTCTCCAGAATTAATGAGCTGACAAACATCGGTGGAAG
ACAGTATCTGGCGGAACTGACCAACAAGGTAGTCAGCTCGGCAAATATTGAATATTATGCCCGGCTGGCAAAAGAGAAAT
ATCTCTATCGACGCCTGATCTCCATTTCCTCAAGAATTTCATCGGCAGCATACAGTTCGGAACTTGATGTCTTTGATCTC
GTCGAGCTTGCCTCCCAGCAGTTCTTCAATATCTCCCAGGCCGGGCTGAAAAAGAAAGCCAGCAATATCAAAGAGCTGCT
GAAAAACGCCACCCGTATGCTGGAAAATCTCAGCGCGTCTCAGTCATCGGTCACGGGAGTCGCGTCGGGATTTTCAGAAC
TCGATGAAATGACGGCCGGATTTCAGCAATCAGACCTCATCATCATCGCCGCCAGACCGTCAGCCGGTAAAACAGCGTTT
GCTCTGGCGCTTGCCCGTAATGCCGCCGTGGACTTCAATACCCCCGTACTGTTTTTCAGCCTCGAGATGGCCGAGGTGCA
GCTTGCCGTCAGATTGATGTGCGCCGAAGCCTGCGTTGAATCCCAGGCGGTCAGGAGCGGTCGGATAACCCCTGAAATGA
TGGGTCTGATCATCAACAGCATGGACGACCTGGCTGAAGCAAAACTCTTTATTGACGACACTCCCGGTATTTCCATCATG
GAGCTGACGGCGAAAGCAAGAAGAATGAAGCAGGAACACAATATCGGTATGATCGTTGTCGATTACCTGCAGCTGGTTTC
ACCGGTACGTGACGGTAAATCAAACAGGGAACAGGAGATCGCCCAGATATCACGATCCCTGAAATTCCTTGCCAAGGAGC
TCAACATAGCAATCATCTCTCTGGCTCAGCTCAACCGCTCAGTTGAACAACGTTCAGGCGACCGTCGTCCGCAGCTGAGC
GACCTTCGCGAATCAGGTTCTATCGAACAGGACGCCGATGTAGTCATGTTTCTTTCAAGACCTGAAATGTACGGCATCAA
AAACTTTGACGATGGAACATCGAGCAAGGATATCGTTGAAATCGTCATCGGCAAGCAACGTAACGGACCAATCGGAGATA
TTCGCTTGCGTTTCCTGAAAAATTACGGCAAATTTCTCTCTACATCGAACGTCTATACCAGTGATAACTATGCTGCCCCC
GAACACACCGGAGGATCGCTTGAGCATGCAGCTCTGCCTGAACTGCCGCCACCGCCATCCGGGCCGGCGCCACCAGACCG
CTTTATTGCTCCGGATGATGCCCCATTTTAG

Upstream 100 bases:

>100_bases
GAGAAACCCCAACTGGAAATACCAATGCTGGGAGGACGTCAAAATGCTGAGAAAACATTTTGATTCAATGTACCAAAGCA
ATCAGCCCTGACAATTGACC

Downstream 100 bases:

>100_bases
GTATCAGCAAGCAATAACTACAGTAATGAGAGCGTCTTAACATTTGTAAGCAGATTCCAATGGAACCCATTCTCCCACAG
AGCGACACAGGCACAAAGAA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKGTIARKGNGGIDLGKDIDFSQESRIPPYSIEVEQEVLACILLEGEPIEQVIQIFGDNDEKVFYEQRHQLIYKAMLELY
QKRLAIDLITVGEELSRINELTNIGGRQYLAELTNKVVSSANIEYYARLAKEKYLYRRLISISSRISSAAYSSELDVFDL
VELASQQFFNISQAGLKKKASNIKELLKNATRMLENLSASQSSVTGVASGFSELDEMTAGFQQSDLIIIAARPSAGKTAF
ALALARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEACVESQAVRSGRITPEMMGLIINSMDDLAEAKLFIDDTPGISIM
ELTAKARRMKQEHNIGMIVVDYLQLVSPVRDGKSNREQEIAQISRSLKFLAKELNIAIISLAQLNRSVEQRSGDRRPQLS
DLRESGSIEQDADVVMFLSRPEMYGIKNFDDGTSSKDIVEIVIGKQRNGPIGDIRLRFLKNYGKFLSTSNVYTSDNYAAP
EHTGGSLEHAALPELPPPPSGPAPPDRFIAPDDAPF

Sequences:

>Translated_516_residues
MKGTIARKGNGGIDLGKDIDFSQESRIPPYSIEVEQEVLACILLEGEPIEQVIQIFGDNDEKVFYEQRHQLIYKAMLELY
QKRLAIDLITVGEELSRINELTNIGGRQYLAELTNKVVSSANIEYYARLAKEKYLYRRLISISSRISSAAYSSELDVFDL
VELASQQFFNISQAGLKKKASNIKELLKNATRMLENLSASQSSVTGVASGFSELDEMTAGFQQSDLIIIAARPSAGKTAF
ALALARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEACVESQAVRSGRITPEMMGLIINSMDDLAEAKLFIDDTPGISIM
ELTAKARRMKQEHNIGMIVVDYLQLVSPVRDGKSNREQEIAQISRSLKFLAKELNIAIISLAQLNRSVEQRSGDRRPQLS
DLRESGSIEQDADVVMFLSRPEMYGIKNFDDGTSSKDIVEIVIGKQRNGPIGDIRLRFLKNYGKFLSTSNVYTSDNYAAP
EHTGGSLEHAALPELPPPPSGPAPPDRFIAPDDAPF
>Mature_516_residues
MKGTIARKGNGGIDLGKDIDFSQESRIPPYSIEVEQEVLACILLEGEPIEQVIQIFGDNDEKVFYEQRHQLIYKAMLELY
QKRLAIDLITVGEELSRINELTNIGGRQYLAELTNKVVSSANIEYYARLAKEKYLYRRLISISSRISSAAYSSELDVFDL
VELASQQFFNISQAGLKKKASNIKELLKNATRMLENLSASQSSVTGVASGFSELDEMTAGFQQSDLIIIAARPSAGKTAF
ALALARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEACVESQAVRSGRITPEMMGLIINSMDDLAEAKLFIDDTPGISIM
ELTAKARRMKQEHNIGMIVVDYLQLVSPVRDGKSNREQEIAQISRSLKFLAKELNIAIISLAQLNRSVEQRSGDRRPQLS
DLRESGSIEQDADVVMFLSRPEMYGIKNFDDGTSSKDIVEIVIGKQRNGPIGDIRLRFLKNYGKFLSTSNVYTSDNYAAP
EHTGGSLEHAALPELPPPPSGPAPPDRFIAPDDAPF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=463, Percent_Identity=42.548596112311, Blast_Score=337, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 57120; Mature: 57120

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTIARKGNGGIDLGKDIDFSQESRIPPYSIEVEQEVLACILLEGEPIEQVIQIFGDND
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHCCCC
EKVFYEQRHQLIYKAMLELYQKRLAIDLITVGEELSRINELTNIGGRQYLAELTNKVVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ANIEYYARLAKEKYLYRRLISISSRISSAAYSSELDVFDLVELASQQFFNISQAGLKKKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHH
SNIKELLKNATRMLENLSASQSSVTGVASGFSELDEMTAGFQQSDLIIIAARPSAGKTAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALALARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEACVESQAVRSGRITPEMMGLIINS
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MDDLAEAKLFIDDTPGISIMELTAKARRMKQEHNIGMIVVDYLQLVSPVRDGKSNREQEI
HHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHH
AQISRSLKFLAKELNIAIISLAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECC
PEMYGIKNFDDGTSSKDIVEIVIGKQRNGPIGDIRLRFLKNYGKFLSTSNVYTSDNYAAP
CCCCCCCCCCCCCCCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EHTGGSLEHAALPELPPPPSGPAPPDRFIAPDDAPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGTIARKGNGGIDLGKDIDFSQESRIPPYSIEVEQEVLACILLEGEPIEQVIQIFGDND
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHCCCC
EKVFYEQRHQLIYKAMLELYQKRLAIDLITVGEELSRINELTNIGGRQYLAELTNKVVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ANIEYYARLAKEKYLYRRLISISSRISSAAYSSELDVFDLVELASQQFFNISQAGLKKKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHH
SNIKELLKNATRMLENLSASQSSVTGVASGFSELDEMTAGFQQSDLIIIAARPSAGKTAF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALALARNAAVDFNTPVLFFSLEMAEVQLAVRLMCAEACVESQAVRSGRITPEMMGLIINS
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MDDLAEAKLFIDDTPGISIMELTAKARRMKQEHNIGMIVVDYLQLVSPVRDGKSNREQEI
HHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHH
AQISRSLKFLAKELNIAIISLAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECC
PEMYGIKNFDDGTSSKDIVEIVIGKQRNGPIGDIRLRFLKNYGKFLSTSNVYTSDNYAAP
CCCCCCCCCCCCCCCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EHTGGSLEHAALPELPPPPSGPAPPDRFIAPDDAPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]