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The map label for this gene is nhaA3 [H]

Identifier: 193213340

GI number: 193213340

Start: 1863053

End: 1864402

Strand: Direct

Name: nhaA3 [H]

Synonym: Cpar_1700

Alternate gene names: 193213340

Gene position: 1863053-1864402 (Clockwise)

Preceding gene: 193213336

Following gene: 193213343

Centisome position: 81.38

GC content: 53.26

Gene sequence:

>1350_bases
ATGATTACAGATCAGCAGGCAAACCCAGAAGCCACCCGATTACCAAAGGAATTTGTTGATCGGCTGACTAAACCTTTTGT
GCGTTTCTTGCACATTCAGTCAGCTAGTGGGGCAATTCTTATATTGTTCACTGTTGCCGCTCTCGTTCTATCCAACTCAC
CGTGGGCCGACTCGTTTGAACATGCCTGGGAGACACAGGTTGGTCTTCAGCTTGGGACGTTCGAGTTTGCCCGTTCGCTG
CGCGAATGGATCAACGATGGTCTGATGACGCTGTTTTTCTTTCTGGTCGCATTGGAGCTTAAGCGAGAGTTAATTCTCGG
AGAGTTGAACAAGCCTCGCATGGCCGCGCTATCCATAGCAGCCGCCCTGGGCGGCATGATCGTCCCGGCTGCGATATATC
TGGCGCTGCAATCAGGACAACCCGGCGAGCATGGATGGGGCACGGTCATGGCAACTGACACGGCGTTTGTCATCGGTTGC
TTGGCACTGCTTGGCTCGCGCATACCTCAAAGCTTACGCGTGTTCATGTTGTCTTTGGCGATCTTTGACGATATCGGTGC
CATTCTTGTCGTCGCCATCGGCTACAGTAGCAACATTGTCTGGGGTGCGTTGGCGCTGGCTACGCTTGGCCTGGTGATTA
TACGCGCCACGGCAATGCTCGGCTTTCGCAGTTTTCCACTCTACTTCCTGGTGGGTGGGGTCATCTGGCTTGCAGTGGAT
GCGTCCGGCATCCACGCCACCATCACTGGCATGATACTTGGTTTGATGACTCCAGCCCGCCGATGGGTCAGCGATGAGCG
CTTGTACGCGATATTGAGTCAGGTTATTGCGCATCCAGCCAGTGGCGAAAGCAGTGCGGATACGAAAGATCGGCAGACAT
TGCAGGTGGCCGAGATTGCCGCGCGTGAAACGCTGTCTCCAGTAGAGCGCCTGGAGATTGGCTTACATCCCTGGGTGGGT
TTTGTCATCATGCCGCTCTTCGCATTTGCCAACGCCGGGTTGCCACTTACTTTAAATGACCTTGGTAATTCAGTCACCGT
GGCAATTTTCTCAGGTTTCGTGCTTGGTAAGCCTGTTGGTATTCTGTTATTTAGCTGGCTAGCTATACGTTTACACATTG
CGATTCGACCCCCAGGACTCGATTGGCGGTTGCTCGCAGGCGGTAGCTTGCTTGCAGGAATTGGCTTCACCATGGCGCTA
TTCATTGCGAATTTGGCTTTCGGCAAGAACCTAATTGACAGTGCCAAGTTGGGAATCTTCCTCGCATCCATGTTTTCCGC
AGTGGCAGGTCTCGCACTGTTGATGTGGTCGCCTACACGTGGAAGAACTCATGAAGTGGATCACGCATGA

Upstream 100 bases:

>100_bases
ACTGTCTGGATGCGTCTTATATGGGCTGAAAATCAAAAATCTGCCTCTTATGCGGATCAGCATAAACAATGTTAGCGCTT
GACGATCGGAAAAACACTTT

Downstream 100 bases:

>100_bases
AAAGCGATTCATAAGAGAATGGAGCAATGACAATGGGTGTGGCTCGTGCTGCCAAAACTGGCGCTAACAAGGCGCTGCAC
TCGGATAAATTACTCGCTGC

Product: Na+/H+ antiporter NhaA

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaA 3 [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MITDQQANPEATRLPKEFVDRLTKPFVRFLHIQSASGAILILFTVAALVLSNSPWADSFEHAWETQVGLQLGTFEFARSL
REWINDGLMTLFFFLVALELKRELILGELNKPRMAALSIAAALGGMIVPAAIYLALQSGQPGEHGWGTVMATDTAFVIGC
LALLGSRIPQSLRVFMLSLAIFDDIGAILVVAIGYSSNIVWGALALATLGLVIIRATAMLGFRSFPLYFLVGGVIWLAVD
ASGIHATITGMILGLMTPARRWVSDERLYAILSQVIAHPASGESSADTKDRQTLQVAEIAARETLSPVERLEIGLHPWVG
FVIMPLFAFANAGLPLTLNDLGNSVTVAIFSGFVLGKPVGILLFSWLAIRLHIAIRPPGLDWRLLAGGSLLAGIGFTMAL
FIANLAFGKNLIDSAKLGIFLASMFSAVAGLALLMWSPTRGRTHEVDHA

Sequences:

>Translated_449_residues
MITDQQANPEATRLPKEFVDRLTKPFVRFLHIQSASGAILILFTVAALVLSNSPWADSFEHAWETQVGLQLGTFEFARSL
REWINDGLMTLFFFLVALELKRELILGELNKPRMAALSIAAALGGMIVPAAIYLALQSGQPGEHGWGTVMATDTAFVIGC
LALLGSRIPQSLRVFMLSLAIFDDIGAILVVAIGYSSNIVWGALALATLGLVIIRATAMLGFRSFPLYFLVGGVIWLAVD
ASGIHATITGMILGLMTPARRWVSDERLYAILSQVIAHPASGESSADTKDRQTLQVAEIAARETLSPVERLEIGLHPWVG
FVIMPLFAFANAGLPLTLNDLGNSVTVAIFSGFVLGKPVGILLFSWLAIRLHIAIRPPGLDWRLLAGGSLLAGIGFTMAL
FIANLAFGKNLIDSAKLGIFLASMFSAVAGLALLMWSPTRGRTHEVDHA
>Mature_449_residues
MITDQQANPEATRLPKEFVDRLTKPFVRFLHIQSASGAILILFTVAALVLSNSPWADSFEHAWETQVGLQLGTFEFARSL
REWINDGLMTLFFFLVALELKRELILGELNKPRMAALSIAAALGGMIVPAAIYLALQSGQPGEHGWGTVMATDTAFVIGC
LALLGSRIPQSLRVFMLSLAIFDDIGAILVVAIGYSSNIVWGALALATLGLVIIRATAMLGFRSFPLYFLVGGVIWLAVD
ASGIHATITGMILGLMTPARRWVSDERLYAILSQVIAHPASGESSADTKDRQTLQVAEIAARETLSPVERLEIGLHPWVG
FVIMPLFAFANAGLPLTLNDLGNSVTVAIFSGFVLGKPVGILLFSWLAIRLHIAIRPPGLDWRLLAGGSLLAGIGFTMAL
FIANLAFGKNLIDSAKLGIFLASMFSAVAGLALLMWSPTRGRTHEVDHA

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3004

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaA Na(+)/H(+) (TC 2.A.33) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1786201, Length=419, Percent_Identity=40.0954653937947, Blast_Score=264, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670 [H]

Pfam domain/function: PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 48343; Mature: 48343

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDQQANPEATRLPKEFVDRLTKPFVRFLHIQSASGAILILFTVAALVLSNSPWADSFE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH
HAWETQVGLQLGTFEFARSLREWINDGLMTLFFFLVALELKRELILGELNKPRMAALSIA
HHHHHHHCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AALGGMIVPAAIYLALQSGQPGEHGWGTVMATDTAFVIGCLALLGSRIPQSLRVFMLSLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IFDDIGAILVVAIGYSSNIVWGALALATLGLVIIRATAMLGFRSFPLYFLVGGVIWLAVD
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATITGMILGLMTPARRWVSDERLYAILSQVIAHPASGESSADTKDRQTLQVAEIA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ARETLSPVERLEIGLHPWVGFVIMPLFAFANAGLPLTLNDLGNSVTVAIFSGFVLGKPVG
HHHHHCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEHHCCCCCEEEHHHHHHHHCCHHH
ILLFSWLAIRLHIAIRPPGLDWRLLAGGSLLAGIGFTMALFIANLAFGKNLIDSAKLGIF
HHHHHHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LASMFSAVAGLALLMWSPTRGRTHEVDHA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MITDQQANPEATRLPKEFVDRLTKPFVRFLHIQSASGAILILFTVAALVLSNSPWADSFE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH
HAWETQVGLQLGTFEFARSLREWINDGLMTLFFFLVALELKRELILGELNKPRMAALSIA
HHHHHHHCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AALGGMIVPAAIYLALQSGQPGEHGWGTVMATDTAFVIGCLALLGSRIPQSLRVFMLSLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHHHHH
IFDDIGAILVVAIGYSSNIVWGALALATLGLVIIRATAMLGFRSFPLYFLVGGVIWLAVD
HHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
ASGIHATITGMILGLMTPARRWVSDERLYAILSQVIAHPASGESSADTKDRQTLQVAEIA
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ARETLSPVERLEIGLHPWVGFVIMPLFAFANAGLPLTLNDLGNSVTVAIFSGFVLGKPVG
HHHHHCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEHHCCCCCEEEHHHHHHHHCCHHH
ILLFSWLAIRLHIAIRPPGLDWRLLAGGSLLAGIGFTMALFIANLAFGKNLIDSAKLGIF
HHHHHHHHHHEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LASMFSAVAGLALLMWSPTRGRTHEVDHA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + 2 Proton [Periplasm] = Na (I) [Periplasm] + 2 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA