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The map label for this gene is pdxJ

Identifier: 193213343

GI number: 193213343

Start: 1865405

End: 1866118

Strand: Direct

Name: pdxJ

Synonym: Cpar_1704

Alternate gene names: 193213343

Gene position: 1865405-1866118 (Clockwise)

Preceding gene: 193213340

Following gene: 193213344

Centisome position: 81.49

GC content: 64.01

Gene sequence:

>714_bases
ATGAGACTCGCCGTTAACATCGACCATATCGCCACCCTGCGCAACGCTCGCAACGAAGGCCATCCCGATCCGGTGGAGGC
CGCCATTCTCGCCGAACAGAGCGGCGCGGCAGGCATCGTCTGCCACTTGCGCGAAGATCGCCGCCACATCAAGGACGACG
ACCTCGAACGGCTTCGTGAAGCCATCGACACCAAGCTCGATCTCGAAATGGCCATGACCAGCGAGATGCAGTCCATCGCG
CTAAGGGTGAAACCCGAGCTGGTGACGCTTGTGCCTGAAAAGCGCGAGGAGCTGACCACCGAGGGCGGCTTCGCGATCCA
CACGCACTTCAAGCGCCTCACAGAGTTCATCAAACCGCTGCGCGACCACGGCGTCGAAGTGAGCATTTTCATCGAGCCCG
AGGACGACGCCATCGAGCTGGCCGCCGAGGCGGGCGCGAACCTCGTGGAGCTGCACACCGGCCCCTACTCGCTCGCCACC
GGCGACAAACAGATAGCCTACGAGCTGGAGCGCATCCGCACTGCGGCTCGCATCGCGCGTGAAGCCGGACTCGCAGTCGT
TGCCGGGCACGGCCTGAGCGTGCACAACATCGCGCCGTTCCGCGAGCTGCACGACATCGAGGAGGTCAGCATCGGTCACG
CCCTCATAGCCCGTGCGGTGCTGGTCGGACTGCCGGTCGCCATTCAGGAACTCCTCGACCACATCTCACGGTGA

Upstream 100 bases:

>100_bases
CGCGTTGTAACATTTTGTATATTTGTTATTAATCGCTATTACCCGATCTTTGACTGACCCCGTGCCGGGGCCGCCTCAAC
TTGTGAAAGGAGCTACGACC

Downstream 100 bases:

>100_bases
GCACCGAAACCATCGACATCGTGCTGGCCACCGGCAACCGCGACAAGGTGCGCGAGCTGAAACCGGTGCTTGAAGGCATT
CATCCCGCGCTCCGGGTACG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLREAIDTKLDLEMAMTSEMQSIA
LRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPLRDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLAT
GDKQIAYELERIRTAARIAREAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR

Sequences:

>Translated_237_residues
MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLREAIDTKLDLEMAMTSEMQSIA
LRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPLRDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLAT
GDKQIAYELERIRTAARIAREAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR
>Mature_237_residues
MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLREAIDTKLDLEMAMTSEMQSIA
LRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPLRDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLAT
GDKQIAYELERIRTAARIAREAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=229, Percent_Identity=51.0917030567686, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_CHLP8 (B3QQ93)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999296.1
- GeneID:   6420645
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1704
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26168; Mature: 26168

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: ACT_SITE 42-42 ACT_SITE 69-69 ACT_SITE 190-190 BINDING 6-6 BINDING 17-17 BINDING 44-44 BINDING 49-49 BINDING 99-99 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLRE
CEEEEEHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCEEEEEEEHHHCCCCCCHHHHHHH
AIDTKLDLEMAMTSEMQSIALRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPL
HHCCHHHHHHHHHHHHHHHHHEECCCEEEECCCHHHHHHCCCCEEHHHHHHHHHHHHHHH
RDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLATGDKQIAYELERIRTAARIAR
HHCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHH
EAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR
HCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLRE
CEEEEEHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCEEEEEEEHHHCCCCCCHHHHHHH
AIDTKLDLEMAMTSEMQSIALRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPL
HHCCHHHHHHHHHHHHHHHHHEECCCEEEECCCHHHHHHCCCCEEHHHHHHHHHHHHHHH
RDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLATGDKQIAYELERIRTAARIAR
HHCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHH
EAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR
HCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA