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The map label for this gene is aroB [H]

Identifier: 193213100

GI number: 193213100

Start: 1592104

End: 1593180

Strand: Direct

Name: aroB [H]

Synonym: Cpar_1455

Alternate gene names: 193213100

Gene position: 1592104-1593180 (Clockwise)

Preceding gene: 193213099

Following gene: 193213101

Centisome position: 69.55

GC content: 46.05

Gene sequence:

>1077_bases
ATGACCGATCTGCTGATCAAGTCGAACATAAGGGACTACAAAGTTGTTTTCGAGAACACGATTGACAGGGTCTCGAAAGC
CATTCAGCCGTTGCCGAACAAAGTGTTGATCGTCGATTCCAATGTTCTGGAAATCTATCGCTCCGACATCGACCGGATGG
CTGATGCAGCCGACATTATCGCCTTCGAAGCGGTCGAAGAGAACAAAAACCTTGAGGCGGTTTCTGGCATCTATTCGTCA
CTGATTGACCGGAATGCCAAACGAAATATCAATTTGGTTTCAATCGGAGGAGGCATAACCCAGGATGTAACCGGTTTCGT
TGCCTCCACGCTCTACCGAGGAGTTAACTGGACGTTCGTACCCACGACCTTTCTAGCCCAGACCGACAGTTGCATTGGTA
GCAAAACCTCTTTGAATTTCGGCAGCCGTAAAAACCTGCTTGGGACTTTTTACCCGCCAGCGACTATCTATCTCTGCCCG
GCATTGCTCTCCTCGCTGACCGAAATCGATTATTACAGCGGCATCGGTGAAACCATCAAGTTTCAGTTGATGAATCCGTT
TGCCAAACCCGACCTTTATCAGATAGCTGAAAAAATCGAACAGGTCAAACGTCATGAAATGCTTGATGAGATCATCAGGG
AAAATATGGCGATCAAAATCGATTACATGGAAAACGATGAATTCGATCTTGGCAGAAGAAATCTGCTCAATTATGGGCAC
TGCTTCGGCCATGCGCTTGAAATATCCTCAGGCTATGCCATACCTCACGGCATAGCCGTTTCGATCGGCATTCTGTTTGC
CGGGACTATATCGGTTTCCAGAGGAGTAATGAGTCAGGAAATGTTAGAAGGTATTAAAAAAATTGTGCTCCCCTGCCTGC
CTATCGCGTTCGATTCGCGGCATTATGATGCGGACTTACTGCTTGCAGCTATGAAAAATGACAAGAAACGCATTGGGGCA
GATTTGAGTATTGTACTTGCCGATAAAGAGTTCATGCTGGCCAAATATGACGATCTCAAGGTGGATGAATTCAGGACGGG
GTTACAAACATTAATTGAAATTTTTGAGAATCAGTGA

Upstream 100 bases:

>100_bases
CCGAGCCTCGGGAGATTGCCGAATCGATCGCGTTTCTGGTCAGCGAGCGCAACTCGTACATGACCGGCCAAACCCTTATT
GTCGACGGGGGATTTATAGC

Downstream 100 bases:

>100_bases
TATGAACAGTATTGAATATCAGATGCTCGATGTCCTCAAACAACTTCGTGATGAGTATGGGGTGTTCGAGATCAAGGCGG
AGTTTGAAGCCGAGGGGAGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTDLLIKSNIRDYKVVFENTIDRVSKAIQPLPNKVLIVDSNVLEIYRSDIDRMADAADIIAFEAVEENKNLEAVSGIYSS
LIDRNAKRNINLVSIGGGITQDVTGFVASTLYRGVNWTFVPTTFLAQTDSCIGSKTSLNFGSRKNLLGTFYPPATIYLCP
ALLSSLTEIDYYSGIGETIKFQLMNPFAKPDLYQIAEKIEQVKRHEMLDEIIRENMAIKIDYMENDEFDLGRRNLLNYGH
CFGHALEISSGYAIPHGIAVSIGILFAGTISVSRGVMSQEMLEGIKKIVLPCLPIAFDSRHYDADLLLAAMKNDKKRIGA
DLSIVLADKEFMLAKYDDLKVDEFRTGLQTLIEIFENQ

Sequences:

>Translated_358_residues
MTDLLIKSNIRDYKVVFENTIDRVSKAIQPLPNKVLIVDSNVLEIYRSDIDRMADAADIIAFEAVEENKNLEAVSGIYSS
LIDRNAKRNINLVSIGGGITQDVTGFVASTLYRGVNWTFVPTTFLAQTDSCIGSKTSLNFGSRKNLLGTFYPPATIYLCP
ALLSSLTEIDYYSGIGETIKFQLMNPFAKPDLYQIAEKIEQVKRHEMLDEIIRENMAIKIDYMENDEFDLGRRNLLNYGH
CFGHALEISSGYAIPHGIAVSIGILFAGTISVSRGVMSQEMLEGIKKIVLPCLPIAFDSRHYDADLLLAAMKNDKKRIGA
DLSIVLADKEFMLAKYDDLKVDEFRTGLQTLIEIFENQ
>Mature_357_residues
TDLLIKSNIRDYKVVFENTIDRVSKAIQPLPNKVLIVDSNVLEIYRSDIDRMADAADIIAFEAVEENKNLEAVSGIYSSL
IDRNAKRNINLVSIGGGITQDVTGFVASTLYRGVNWTFVPTTFLAQTDSCIGSKTSLNFGSRKNLLGTFYPPATIYLCPA
LLSSLTEIDYYSGIGETIKFQLMNPFAKPDLYQIAEKIEQVKRHEMLDEIIRENMAIKIDYMENDEFDLGRRNLLNYGHC
FGHALEISSGYAIPHGIAVSIGILFAGTISVSRGVMSQEMLEGIKKIVLPCLPIAFDSRHYDADLLLAAMKNDKKRIGAD
LSIVLADKEFMLAKYDDLKVDEFRTGLQTLIEIFENQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=340, Percent_Identity=27.9411764705882, Blast_Score=125, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=298, Percent_Identity=29.1946308724832, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40049; Mature: 39917

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLLIKSNIRDYKVVFENTIDRVSKAIQPLPNKVLIVDSNVLEIYRSDIDRMADAADII
CCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
AFEAVEENKNLEAVSGIYSSLIDRNAKRNINLVSIGGGITQDVTGFVASTLYRGVNWTFV
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
PTTFLAQTDSCIGSKTSLNFGSRKNLLGTFYPPATIYLCPALLSSLTEIDYYSGIGETIK
CHHHHHHCCHHCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
FQLMNPFAKPDLYQIAEKIEQVKRHEMLDEIIRENMAIKIDYMENDEFDLGRRNLLNYGH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHH
CFGHALEISSGYAIPHGIAVSIGILFAGTISVSRGVMSQEMLEGIKKIVLPCLPIAFDSR
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
HYDADLLLAAMKNDKKRIGADLSIVLADKEFMLAKYDDLKVDEFRTGLQTLIEIFENQ
CCCHHHHHHHHHCCHHHHCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDLLIKSNIRDYKVVFENTIDRVSKAIQPLPNKVLIVDSNVLEIYRSDIDRMADAADII
CCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
AFEAVEENKNLEAVSGIYSSLIDRNAKRNINLVSIGGGITQDVTGFVASTLYRGVNWTFV
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEE
PTTFLAQTDSCIGSKTSLNFGSRKNLLGTFYPPATIYLCPALLSSLTEIDYYSGIGETIK
CHHHHHHCCHHCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
FQLMNPFAKPDLYQIAEKIEQVKRHEMLDEIIRENMAIKIDYMENDEFDLGRRNLLNYGH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHH
CFGHALEISSGYAIPHGIAVSIGILFAGTISVSRGVMSQEMLEGIKKIVLPCLPIAFDSR
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
HYDADLLLAAMKNDKKRIGADLSIVLADKEFMLAKYDDLKVDEFRTGLQTLIEIFENQ
CCCHHHHHHHHHCCHHHHCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]