BacMap

Definition	Chlorobaculum parvum NCIB 8327 chromosome, complete genome.
Accession	NC_011027
Length	2,289,249

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The map label for this gene is fabG [H]

Identifier: 193213099

GI number: 193213099

Start: 1591442

End: 1592107

Strand: Direct

Name: fabG [H]

Synonym: Cpar_1454

Alternate gene names: 193213099

Gene position: 1591442-1592107 (Clockwise)

Preceding gene: 193213098

Following gene: 193213100

Centisome position: 69.52

GC content: 52.1

Gene sequence:

>666_bases
ATGAAGATTAAGAAGATTCTGGTTACCGGCGGCACAGGGGGGATCGGATCCTCGATAGTCGCTTGCTTGTCCGCACAGCC
TGGCTTTGTCGTCCACGCTCCCAGCCGGAGCGAGCTTGATCTGGGCTTGCAGGAGAGCATTAAAGAATATTTTTCCCGGA
GTTCAGACTATGATATTGTTATTAACAATGCCGGGATCAACACTCCACAAAACATCGAACAGATCGAAACTGAGCAGATC
GAAACTGCCCTGAACATCAATCTTGTCGCCCCTCTTCTTGTCATCAAGTACTGCGTACCGCACATGAAGCGACAAGGTTT
TGGGCGAATCGTCAACGTCAGCTCGATCTGGGGGATTCGCTCAAAGGAGAGACGAACCCTCTACTCGGCTACCAAGTTTG
GCCTAAACGGTATGACCAGATCACTTGCCAGAGAACTCGGGCCGTTCAATATACTGGTCAACTCGATCTGTCCCGGCTAT
GTCGATACAGCCCTGACCCGGAAAAACGTGACGCCAAAGGAGCAGGAAAAGATCAGGCAGGAAATTCCGCTGCGGCGCTT
TGCCGAGCCTCGGGAGATTGCCGAATCGATCGCGTTTCTGGTCAGCGAGCGCAACTCGTACATGACCGGCCAAACCCTTA
TTGTCGACGGGGGATTTATAGCATGA

Upstream 100 bases:

>100_bases
GTCAAGTCTGATGGCAGAATCGTCTCCAAACCGCTCGAAGACATGTTCCCGTTTCTCGATCGTGATGTATTCAATCAACA
GATGATTATCGGAACCATTG

Downstream 100 bases:

>100_bases
CCGATCTGCTGATCAAGTCGAACATAAGGGACTACAAAGTTGTTTTCGAGAACACGATTGACAGGGTCTCGAAAGCCATT
CAGCCGTTGCCGAACAAAGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKIKKILVTGGTGGIGSSIVACLSAQPGFVVHAPSRSELDLGLQESIKEYFSRSSDYDIVINNAGINTPQNIEQIETEQI
ETALNINLVAPLLVIKYCVPHMKRQGFGRIVNVSSIWGIRSKERRTLYSATKFGLNGMTRSLARELGPFNILVNSICPGY
VDTALTRKNVTPKEQEKIRQEIPLRRFAEPREIAESIAFLVSERNSYMTGQTLIVDGGFIA

Sequences:

>Translated_221_residues
MKIKKILVTGGTGGIGSSIVACLSAQPGFVVHAPSRSELDLGLQESIKEYFSRSSDYDIVINNAGINTPQNIEQIETEQI
ETALNINLVAPLLVIKYCVPHMKRQGFGRIVNVSSIWGIRSKERRTLYSATKFGLNGMTRSLARELGPFNILVNSICPGY
VDTALTRKNVTPKEQEKIRQEIPLRRFAEPREIAESIAFLVSERNSYMTGQTLIVDGGFIA
>Mature_221_residues
MKIKKILVTGGTGGIGSSIVACLSAQPGFVVHAPSRSELDLGLQESIKEYFSRSSDYDIVINNAGINTPQNIEQIETEQI
ETALNINLVAPLLVIKYCVPHMKRQGFGRIVNVSSIWGIRSKERRTLYSATKFGLNGMTRSLARELGPFNILVNSICPGY
VDTALTRKNVTPKEQEKIRQEIPLRRFAEPREIAESIAFLVSERNSYMTGQTLIVDGGFIA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=32.9059829059829, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483357, Length=164, Percent_Identity=38.4146341463415, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=31.6455696202532, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI15277342, Length=178, Percent_Identity=33.7078651685393, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI126723750, Length=146, Percent_Identity=35.6164383561644, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=29.9465240641711, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI59889578, Length=178, Percent_Identity=32.0224719101124, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI10190704, Length=178, Percent_Identity=30.3370786516854, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI223718074, Length=205, Percent_Identity=26.3414634146341, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=164, Percent_Identity=29.8780487804878, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=237, Percent_Identity=25.3164556962025, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7657478, Length=133, Percent_Identity=30.8270676691729, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI109715829, Length=229, Percent_Identity=27.0742358078603, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI210032110, Length=143, Percent_Identity=29.3706293706294, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=26.5, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=29.045643153527, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=34.8066298342541, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.4552845528455, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=31.5573770491803, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789208, Length=166, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=197, Percent_Identity=27.4111675126904, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI2367365, Length=235, Percent_Identity=28.0851063829787, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=28.8065843621399, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=167, Percent_Identity=30.5389221556886, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789057, Length=203, Percent_Identity=29.064039408867, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786812, Length=170, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=26.5060240963855, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=37.1428571428571, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=31.8181818181818, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=32.2175732217573, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=32.2175732217573, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=35.0194552529183, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=193, Percent_Identity=33.160621761658, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=170, Percent_Identity=32.9411764705882, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=29.4573643410853, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=166, Percent_Identity=33.1325301204819, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=30.2325581395349, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=29.6153846153846, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=32.6530612244898, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=28.6821705426357, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=27.2373540856031, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=195, Percent_Identity=31.7948717948718, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=28.125, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=215, Percent_Identity=28.3720930232558, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=177, Percent_Identity=29.9435028248588, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=27.2, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=234, Percent_Identity=32.0512820512821, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI23397609, Length=241, Percent_Identity=29.8755186721992, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=32.8125, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=31.0483870967742, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=28.3400809716599, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=166, Percent_Identity=33.1325301204819, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=111, Percent_Identity=34.2342342342342, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24430; Mature: 24430

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKILVTGGTGGIGSSIVACLSAQPGFVVHAPSRSELDLGLQESIKEYFSRSSDYDIV
CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEE
INNAGINTPQNIEQIETEQIETALNINLVAPLLVIKYCVPHMKRQGFGRIVNVSSIWGIR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCC
SKERRTLYSATKFGLNGMTRSLARELGPFNILVNSICPGYVDTALTRKNVTPKEQEKIRQ
CHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
EIPLRRFAEPREIAESIAFLVSERNSYMTGQTLIVDGGFIA
HCCHHHCCCHHHHHHHHHHHHHHCCCEECCCEEEECCCCCC
>Mature Secondary Structure
MKIKKILVTGGTGGIGSSIVACLSAQPGFVVHAPSRSELDLGLQESIKEYFSRSSDYDIV
CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEE
INNAGINTPQNIEQIETEQIETALNINLVAPLLVIKYCVPHMKRQGFGRIVNVSSIWGIR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCC
SKERRTLYSATKFGLNGMTRSLARELGPFNILVNSICPGYVDTALTRKNVTPKEQEKIRQ
CHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
EIPLRRFAEPREIAESIAFLVSERNSYMTGQTLIVDGGFIA
HCCHHHCCCHHHHHHHHHHHHHHCCCEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]