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The map label for this gene is idhA [H]

Identifier: 190895035

GI number: 190895035

Start: 760598

End: 761590

Strand: Reverse

Name: idhA [H]

Synonym: RHECIAT_PC0000701

Alternate gene names: 190895035

Gene position: 761590-760598 (Counterclockwise)

Preceding gene: 190895036

Following gene: 190895032

Centisome position: 69.77

GC content: 60.02

Gene sequence:

>993_bases
ATGATCAGATTTGGAGTGATCGGCGCCGGCCGAATAGGCAAAGTGCATGCCACAACGATCGCGGCGAACCCCAATGCGAA
GCTTGCTTATGTGGCGGATGCCTTCAAGGCTTCAGCTGAAGAGCTTGCCGCGCGGACGGGCGCCGAGGTTGCCGAGGCGG
AGGACGTCATTAAGTCCCCGAACGTCGATGCGATCCTCATTGCGACGCCGACCCCGAGTCATGCCGATCTGATCGAGGCG
GCGGCGCGCGCCGGCAAGGCCATTCTCTGCGAAAAGCCAGTATCCCTGTCGGTCGACCGCATCAATGCCTGCCTCGAGGT
TGTCGAGAAAAACAGATCGACTTTGATGATTGGCTTCAATCGCCGCTTTGACCCGAACTTCGCGAGTGTGGAAGCGCGCC
TGCGCCATGGCGATGTCGGCGCAATCGAAATCGTGACGATCACCAGCCGGGATCCAGCGCCGCCGCCTGCCGACTACGTC
AAATCCTCCGGTGGTCTGTTCCGCGACATGATGATTCACGACTTCGACATGGCTCGCTTTCTCATGGGCGAGGAATTCGT
GGTCGTGAACGCGCTCGGGTCGTCTCTCGTCGACAAGGCAATCGGGGCCGAGGGCGATGTGGATACCGCCGCCGTGCAGA
TGCAGACGGCGTCAGGCCGCATTGCCGTGATCACCAATTCGCGCCGGGCGACCTATGGCTACGACCAGCGTATCGAAGTC
CATGGAGCTGCCGGTATGCTTGCGGCGAAGAATATCCATGCGACGAGCGTCGAGCTTTCCAATGCAAACGGCGTCAGCGG
CGATCCTGTTCAATATTTCTTTCTCGAACGCTATGCACAGGCTTACGCCAACGAGATCAACGCCTTCATCGAAGCGATCG
ACAGTGGCAACTCCTCGCCGAGGCCAGGGGGGCTCGATGGCCTTCAGGCTCAGAAATTGGCAGAGGCCGCCACTGTGAGC
TGGCAGACAGGCAGGCCAGTTGCCGTCAATTGA

Upstream 100 bases:

>100_bases
GGCCTCGGGTGATGACGAGACGGCGCTTGCCCGCTTCCGCGACGCCTTCACCGTTTGAAGATTTGGATAGTCAAGACTTA
CAGTTAATGGAGAGACATCA

Downstream 100 bases:

>100_bases
CGTCATGGCGATGCAGTCCGGTCCACACCGCTTGCTGCATCGCCCATCCCCTAAATGCGACGACTTATCCTTCGCGAATG
CATCTGCCACGGAGGCGCCA

Product: putative myo-inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIRFGVIGAGRIGKVHATTIAANPNAKLAYVADAFKASAEELAARTGAEVAEAEDVIKSPNVDAILIATPTPSHADLIEA
AARAGKAILCEKPVSLSVDRINACLEVVEKNRSTLMIGFNRRFDPNFASVEARLRHGDVGAIEIVTITSRDPAPPPADYV
KSSGGLFRDMMIHDFDMARFLMGEEFVVVNALGSSLVDKAIGAEGDVDTAAVQMQTASGRIAVITNSRRATYGYDQRIEV
HGAAGMLAAKNIHATSVELSNANGVSGDPVQYFFLERYAQAYANEINAFIEAIDSGNSSPRPGGLDGLQAQKLAEAATVS
WQTGRPVAVN

Sequences:

>Translated_330_residues
MIRFGVIGAGRIGKVHATTIAANPNAKLAYVADAFKASAEELAARTGAEVAEAEDVIKSPNVDAILIATPTPSHADLIEA
AARAGKAILCEKPVSLSVDRINACLEVVEKNRSTLMIGFNRRFDPNFASVEARLRHGDVGAIEIVTITSRDPAPPPADYV
KSSGGLFRDMMIHDFDMARFLMGEEFVVVNALGSSLVDKAIGAEGDVDTAAVQMQTASGRIAVITNSRRATYGYDQRIEV
HGAAGMLAAKNIHATSVELSNANGVSGDPVQYFFLERYAQAYANEINAFIEAIDSGNSSPRPGGLDGLQAQKLAEAATVS
WQTGRPVAVN
>Mature_330_residues
MIRFGVIGAGRIGKVHATTIAANPNAKLAYVADAFKASAEELAARTGAEVAEAEDVIKSPNVDAILIATPTPSHADLIEA
AARAGKAILCEKPVSLSVDRINACLEVVEKNRSTLMIGFNRRFDPNFASVEARLRHGDVGAIEIVTITSRDPAPPPADYV
KSSGGLFRDMMIHDFDMARFLMGEEFVVVNALGSSLVDKAIGAEGDVDTAAVQMQTASGRIAVITNSRRATYGYDQRIEV
HGAAGMLAAKNIHATSVELSNANGVSGDPVQYFFLERYAQAYANEINAFIEAIDSGNSSPRPGGLDGLQAQKLAEAATVS
WQTGRPVAVN

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87081947, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082405, Length=236, Percent_Identity=26.271186440678, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787574, Length=225, Percent_Identity=24.8888888888889, Blast_Score=61, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24581117, Length=239, Percent_Identity=24.2677824267782, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 34900; Mature: 34900

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFGVIGAGRIGKVHATTIAANPNAKLAYVADAFKASAEELAARTGAEVAEAEDVIKSP
CEEEEEECCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
NVDAILIATPTPSHADLIEAAARAGKAILCEKPVSLSVDRINACLEVVEKNRSTLMIGFN
CCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
RRFDPNFASVEARLRHGDVGAIEIVTITSRDPAPPPADYVKSSGGLFRDMMIHDFDMARF
CCCCCCHHHHHHEEECCCCCEEEEEEEECCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHH
LMGEEFVVVNALGSSLVDKAIGAEGDVDTAAVQMQTASGRIAVITNSRRATYGYDQRIEV
HHCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCCEECCCCCEEEE
HGAAGMLAAKNIHATSVELSNANGVSGDPVQYFFLERYAQAYANEINAFIEAIDSGNSSP
ECCCCEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RPGGLDGLQAQKLAEAATVSWQTGRPVAVN
CCCCCCCHHHHHHHHHHEEEECCCCCEECC
>Mature Secondary Structure
MIRFGVIGAGRIGKVHATTIAANPNAKLAYVADAFKASAEELAARTGAEVAEAEDVIKSP
CEEEEEECCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
NVDAILIATPTPSHADLIEAAARAGKAILCEKPVSLSVDRINACLEVVEKNRSTLMIGFN
CCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
RRFDPNFASVEARLRHGDVGAIEIVTITSRDPAPPPADYVKSSGGLFRDMMIHDFDMARF
CCCCCCHHHHHHEEECCCCCEEEEEEEECCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHH
LMGEEFVVVNALGSSLVDKAIGAEGDVDTAAVQMQTASGRIAVITNSRRATYGYDQRIEV
HHCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCCEECCCCCEEEE
HGAAGMLAAKNIHATSVELSNANGVSGDPVQYFFLERYAQAYANEINAFIEAIDSGNSSP
ECCCCEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RPGGLDGLQAQKLAEAATVSWQTGRPVAVN
CCCCCCCHHHHHHHHHHEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]