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The map label for this gene is tenA [H]

Identifier: 190571524

GI number: 190571524

Start: 1226900

End: 1227565

Strand: Direct

Name: tenA [H]

Synonym: WPa_1143

Alternate gene names: 190571524

Gene position: 1226900-1227565 (Clockwise)

Preceding gene: 190571523

Following gene: 190571525

Centisome position: 82.76

GC content: 31.53

Gene sequence:

>666_bases
ATGTCCAACAAACCAAAAGAAGAATTTTATGATATTGCTATAAAAGAATCATCTGATCTTATTGAAGAAATAAAAGAACA
TCCTTTCAATGTTGAATTGATAAACAATACGCTAGATTATGAAAAGTTCAAAATTTATCTTCAGCAGGATTTTTTATATT
TAGTGGACTGTACTCGTGCTTTATTGATTATTGCAGCTAAAGTTGATGACATTGAAATAATGGGCAGTTTGGTTAATGTA
GCAAGGGGAACATTTGCGGTTCGAAAGCAGTATACTGAATATTTTGAGACTTGTGATTTATCCGATAATCATAAAAAATC
AAAATCTTGTTCTGCTTTTACTGATTTTTTTATGCGTGCTGCATATCATAATTCTGTTGCTGAAGCTTTAGCAGCGTCTT
ATCCTTGTTTTAATATATACCAAATTATTATAAATCATATGGTAGGAGAGGTTATGCCTAAAAAAGTTGAAGATCACAGA
TATCAAGGGTGGATTGATATCTATAATAACACAGTAATGAATGCTACGATTAATCAAGTTACTGACGTTGCAAATAATCT
ATATGCAAAGGCTGGTGATTGTGAGAGGAAAAAGATGCGTGAGTTTTTTAAGAGAGGTCTAGAGCTAGAAATAATGTTTT
GGGATGAGATGTATTCTCTAGCATAA

Upstream 100 bases:

>100_bases
CTCTTTTATTTCTAGCTTGATACTGATATAATAACTTATTATAAATTGTAAGTAACTTTTTAGTAACCATACTAGTTTTA
ATATTTATGAGGCTTACAAG

Downstream 100 bases:

>100_bases
TCTGTAGTATTAACACTAAATTATATTCTAGTTTATGTGATGTTTAGTGGTATAATTAAGAGTTATTATGGGTCAAATCT
TTTAAAGGATATTATTGAGC

Product: Putative transcriptional activator, tenA family

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSNKPKEEFYDIAIKESSDLIEEIKEHPFNVELINNTLDYEKFKIYLQQDFLYLVDCTRALLIIAAKVDDIEIMGSLVNV
ARGTFAVRKQYTEYFETCDLSDNHKKSKSCSAFTDFFMRAAYHNSVAEALAASYPCFNIYQIIINHMVGEVMPKKVEDHR
YQGWIDIYNNTVMNATINQVTDVANNLYAKAGDCERKKMREFFKRGLELEIMFWDEMYSLA

Sequences:

>Translated_221_residues
MSNKPKEEFYDIAIKESSDLIEEIKEHPFNVELINNTLDYEKFKIYLQQDFLYLVDCTRALLIIAAKVDDIEIMGSLVNV
ARGTFAVRKQYTEYFETCDLSDNHKKSKSCSAFTDFFMRAAYHNSVAEALAASYPCFNIYQIIINHMVGEVMPKKVEDHR
YQGWIDIYNNTVMNATINQVTDVANNLYAKAGDCERKKMREFFKRGLELEIMFWDEMYSLA
>Mature_220_residues
SNKPKEEFYDIAIKESSDLIEEIKEHPFNVELINNTLDYEKFKIYLQQDFLYLVDCTRALLIIAAKVDDIEIMGSLVNVA
RGTFAVRKQYTEYFETCDLSDNHKKSKSCSAFTDFFMRAAYHNSVAEALAASYPCFNIYQIIINHMVGEVMPKKVEDHRY
QGWIDIYNNTVMNATINQVTDVANNLYAKAGDCERKKMREFFKRGLELEIMFWDEMYSLA

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 25797; Mature: 25666

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKPKEEFYDIAIKESSDLIEEIKEHPFNVELINNTLDYEKFKIYLQQDFLYLVDCTRA
CCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLIIAAKVDDIEIMGSLVNVARGTFAVRKQYTEYFETCDLSDNHKKSKSCSAFTDFFMRA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AYHNSVAEALAASYPCFNIYQIIINHMVGEVMPKKVEDHRYQGWIDIYNNTVMNATINQV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEHHCCEEHHHHHHHH
TDVANNLYAKAGDCERKKMREFFKRGLELEIMFWDEMYSLA
HHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHCC
>Mature Secondary Structure 
SNKPKEEFYDIAIKESSDLIEEIKEHPFNVELINNTLDYEKFKIYLQQDFLYLVDCTRA
CCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLIIAAKVDDIEIMGSLVNVARGTFAVRKQYTEYFETCDLSDNHKKSKSCSAFTDFFMRA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AYHNSVAEALAASYPCFNIYQIIINHMVGEVMPKKVEDHRYQGWIDIYNNTVMNATINQV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEHHCCEEHHHHHHHH
TDVANNLYAKAGDCERKKMREFFKRGLELEIMFWDEMYSLA
HHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]