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The map label for this gene is pqqL [C]

Identifier: 190571000

GI number: 190571000

Start: 637666

End: 638940

Strand: Reverse

Name: pqqL [C]

Synonym: WPa_0591

Alternate gene names: 190571000

Gene position: 638940-637666 (Counterclockwise)

Preceding gene: 190571001

Following gene: 190570996

Centisome position: 43.1

GC content: 34.59

Gene sequence:

>1275_bases
ATGAATATACCACAAGTAACAAAACTAGATAATGGTCTGCGCATAATAACTGAGCGAGTGCATGAAGTTGATTCCGTAGC
TTTAAATATACGAGTTGGTGTTGGCAGTAGAGCTGAAAGTGCAAGTCAAAATGGAATATCTCATTTCCTAGAGCACATGG
CTTTCAAAGGAACAAAGACAAGAACTGCTTTTGAAATTGCAAAAGCTTTTGACGATATAGGTGGAGCCTTCAATGCCTGC
ACCGGTAGAGAAAGCACCAGTTATTATGCAAAGGTTCTTAAAAAAGATATAAAAACTGGCATTGATATATTAATAGATAT
ATTAATGAATTCTACATTTCCAGAGGATGAATTGGAACGCGAAAAGGGTGTTGTAATACAAGAGATTTTTCAAACCAATG
ATTCACCAAGTGATATCATTTTTGATAAGTATTTTGAAGCAGCTTATAAAGATCAACCATTTGGTAGGTCAATCTTGGGT
ACGCAAGATACTGTTAAATCTTTTACTCGAGCTAATCTAGATAACTATATAAATGAGCATTACTTTGGCGAGAACATTAT
ATTTGCTGTTGCAGGAAATGTTGAACATGAGGAGGTTGTTCAATTAATCAAAGACTTTCTCTCAAAGATTCATTCAAAAG
AGCTAAAAAAAAGCGAGAATGCAAGTTATACCGGTGGTGAGTATTTAGAACATCGTAAATTAGATCAGGTGCACTTGTTA
ATTGGGCTACCTAGTGTTTCTCGTGATGATAATAAATATCACACATTTAAAGTCCTTGATTCTATACTGGGAAGTGGCAT
GTCATCACGCCTGTTTCAGGAAGTAAGAGAAAAGCAGGGTCTTGCTTACTCCATTTACTCATTCAACTCTAGCTATGCTG
ATACGGGAATGCTTTCGATTTTTGCTGGTACAGATAGTAGTAATCTAGATAAGCTTTTAAAATCCATAACGACAGAGCTA
AAGAAATTGTCTACAGATGATTTAAAGGAAGAAGAAGTAAATAGAGTAAAAGAACGAGTAAAATCTCAAATTTTAATGTC
ACGCGAAAGTGTTAGCTCACGTGCTGAAACATTAGGACACTACTACGGTAACTATAATAAATACATCAGTAAAAATGAAT
TAATAGAAAAAATTAGTGCTGTTACTATTTACGATATAAAAAAAGCAGCAGAAGAATTGCTATCTCAGCATGAGAGAATT
ACTTTAGCTGCGATTGGAGAAATTAAGTCACTGCCAAGTTACGATAAAGTTGTTTCTATGCTTAGTGTACTTTAA

Upstream 100 bases:

>100_bases
TTGGATTGCCAAAATCGCAGAATTGACTACATAAAAGTTTTTCTTGATCATTTGATCAATTGGGATTTTGTAGAAGAGAA
TTTAAAGAAGAATATATAAG

Downstream 100 bases:

>100_bases
TTATGTTGCTTATGCTCACTAAAAAGTTCAATGAATGGTTGCAAAATCCTTTCTATAAAAAGTTTCCTTTCTGGTTCATC
GCGTATACCACTAATTATTT

Product: peptidase, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNIPQVTKLDNGLRIITERVHEVDSVALNIRVGVGSRAESASQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGAFNAC
TGRESTSYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIIFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRANLDNYINEHYFGENIIFAVAGNVEHEEVVQLIKDFLSKIHSKELKKSENASYTGGEYLEHRKLDQVHLL
IGLPSVSRDDNKYHTFKVLDSILGSGMSSRLFQEVREKQGLAYSIYSFNSSYADTGMLSIFAGTDSSNLDKLLKSITTEL
KKLSTDDLKEEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNKYISKNELIEKISAVTIYDIKKAAEELLSQHERI
TLAAIGEIKSLPSYDKVVSMLSVL

Sequences:

>Translated_424_residues
MNIPQVTKLDNGLRIITERVHEVDSVALNIRVGVGSRAESASQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGAFNAC
TGRESTSYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIIFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRANLDNYINEHYFGENIIFAVAGNVEHEEVVQLIKDFLSKIHSKELKKSENASYTGGEYLEHRKLDQVHLL
IGLPSVSRDDNKYHTFKVLDSILGSGMSSRLFQEVREKQGLAYSIYSFNSSYADTGMLSIFAGTDSSNLDKLLKSITTEL
KKLSTDDLKEEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNKYISKNELIEKISAVTIYDIKKAAEELLSQHERI
TLAAIGEIKSLPSYDKVVSMLSVL
>Mature_424_residues
MNIPQVTKLDNGLRIITERVHEVDSVALNIRVGVGSRAESASQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGAFNAC
TGRESTSYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIIFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRANLDNYINEHYFGENIIFAVAGNVEHEEVVQLIKDFLSKIHSKELKKSENASYTGGEYLEHRKLDQVHLL
IGLPSVSRDDNKYHTFKVLDSILGSGMSSRLFQEVREKQGLAYSIYSFNSSYADTGMLSIFAGTDSSNLDKLLKSITTEL
KKLSTDDLKEEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNKYISKNELIEKISAVTIYDIKKAAEELLSQHERI
TLAAIGEIKSLPSYDKVVSMLSVL

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=440, Percent_Identity=32.9545454545455, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI46593007, Length=435, Percent_Identity=27.5862068965517, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI24308013, Length=450, Percent_Identity=26.8888888888889, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI50592988, Length=433, Percent_Identity=24.9422632794457, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1787770, Length=232, Percent_Identity=29.7413793103448, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71999683, Length=430, Percent_Identity=26.2790697674419, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17553678, Length=442, Percent_Identity=25.1131221719457, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17510601, Length=448, Percent_Identity=22.9910714285714, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17569737, Length=426, Percent_Identity=21.830985915493, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555260, Length=420, Percent_Identity=19.047619047619, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=427, Percent_Identity=33.2552693208431, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321813, Length=412, Percent_Identity=25.7281553398058, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319426, Length=445, Percent_Identity=24.0449438202247, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357875, Length=441, Percent_Identity=31.9727891156463, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24646943, Length=441, Percent_Identity=31.9727891156463, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI19921772, Length=457, Percent_Identity=25.601750547046, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24665395, Length=398, Percent_Identity=22.3618090452261, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47699; Mature: 47699

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPQVTKLDNGLRIITERVHEVDSVALNIRVGVGSRAESASQNGISHFLEHMAFKGTKT
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCH
RTAFEIAKAFDDIGGAFNACTGRESTSYYAKVLKKDIKTGIDILIDILMNSTFPEDELER
HHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKGVVIQEIFQTNDSPSDIIFDKYFEAAYKDQPFGRSILGTQDTVKSFTRANLDNYINEH
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YFGENIIFAVAGNVEHEEVVQLIKDFLSKIHSKELKKSENASYTGGEYLEHRKLDQVHLL
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEE
IGLPSVSRDDNKYHTFKVLDSILGSGMSSRLFQEVREKQGLAYSIYSFNSSYADTGMLSI
EECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEE
FAGTDSSNLDKLLKSITTELKKLSTDDLKEEEVNRVKERVKSQILMSRESVSSRAETLGH
EECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYGNYNKYISKNELIEKISAVTIYDIKKAAEELLSQHERITLAAIGEIKSLPSYDKVVSM
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHCCCCHHHHHHH
LSVL
HHHC
>Mature Secondary Structure
MNIPQVTKLDNGLRIITERVHEVDSVALNIRVGVGSRAESASQNGISHFLEHMAFKGTKT
CCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCH
RTAFEIAKAFDDIGGAFNACTGRESTSYYAKVLKKDIKTGIDILIDILMNSTFPEDELER
HHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKGVVIQEIFQTNDSPSDIIFDKYFEAAYKDQPFGRSILGTQDTVKSFTRANLDNYINEH
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YFGENIIFAVAGNVEHEEVVQLIKDFLSKIHSKELKKSENASYTGGEYLEHRKLDQVHLL
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEE
IGLPSVSRDDNKYHTFKVLDSILGSGMSSRLFQEVREKQGLAYSIYSFNSSYADTGMLSI
EECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEE
FAGTDSSNLDKLLKSITTELKKLSTDDLKEEEVNRVKERVKSQILMSRESVSSRAETLGH
EECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYGNYNKYISKNELIEKISAVTIYDIKKAAEELLSQHERITLAAIGEIKSLPSYDKVVSM
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHCCCCHHHHHHH
LSVL
HHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA