Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 190570920

GI number: 190570920

Start: 537965

End: 538441

Strand: Direct

Name: lspA [H]

Synonym: WPa_0500

Alternate gene names: 190570920

Gene position: 537965-538441 (Clockwise)

Preceding gene: 190570919

Following gene: 190570921

Centisome position: 36.29

GC content: 30.82

Gene sequence:

>477_bases
ATGAAAAGGATATGTTTAGTTATTATATTGATTATAGTATCATTCGATCAAACAAGTAAATTGTATATAAACTCATTGAT
TGATGAGGGGGAGTCAATCGAGATTACTAGTTTTATGAAATTAGTTGAAGTTTGGAATTCAGGAATTAGCTTTGGAATGT
GTAGTACTCTACCGCATGGCAGCTTCTTTTTTTCGGCATGTTCAATATTAATAATTGGTATACTTGCATACTTGATATAT
AAATCTAATGATAAGTCAATTTACCTTAGTTTTTCTCTGATGATTGGTGGAGCGATCGGAAATGTAATTGATAGAATCTA
TTGGGGCGCTGTATATGATTTCATATATTTTCATATCAATGATTGGTATTGGCCAGCCTTTAATTTAGCAGATCTATCTA
TAGTTTGTGGAATGTGTACATTGTTATATAAGTGGTATATATATGATAGGTCTATCTCTAAGCAAAATGAGGAATGA

Upstream 100 bases:

>100_bases
TAAAATTTATTAGGGCAGAAAAAAAATTCCATAGTATTAACGAGTTAACAAAACAGATAGACCGTGATATAATGAAGGCT
TACCAGTTAAAGATAAACTT

Downstream 100 bases:

>100_bases
AATAATGCTTCGCAAATTCTTTAGTTTTTTTATACTATCTGTGTTTTTTTTCATTTGTCCGATTTCTTTGGAAGCTGAAA
TCATAAAGCATGCTAAGCTC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MKRICLVIILIIVSFDQTSKLYINSLIDEGESIEITSFMKLVEVWNSGISFGMCSTLPHGSFFFSACSILIIGILAYLIY
KSNDKSIYLSFSLMIGGAIGNVIDRIYWGAVYDFIYFHINDWYWPAFNLADLSIVCGMCTLLYKWYIYDRSISKQNEE

Sequences:

>Translated_158_residues
MKRICLVIILIIVSFDQTSKLYINSLIDEGESIEITSFMKLVEVWNSGISFGMCSTLPHGSFFFSACSILIIGILAYLIY
KSNDKSIYLSFSLMIGGAIGNVIDRIYWGAVYDFIYFHINDWYWPAFNLADLSIVCGMCTLLYKWYIYDRSISKQNEE
>Mature_158_residues
MKRICLVIILIIVSFDQTSKLYINSLIDEGESIEITSFMKLVEVWNSGISFGMCSTLPHGSFFFSACSILIIGILAYLIY
KSNDKSIYLSFSLMIGGAIGNVIDRIYWGAVYDFIYFHINDWYWPAFNLADLSIVCGMCTLLYKWYIYDRSISKQNEE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=154, Percent_Identity=29.8701298701299, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18161; Mature: 18161

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRICLVIILIIVSFDQTSKLYINSLIDEGESIEITSFMKLVEVWNSGISFGMCSTLPHG
CHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
SFFFSACSILIIGILAYLIYKSNDKSIYLSFSLMIGGAIGNVIDRIYWGAVYDFIYFHIN
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
DWYWPAFNLADLSIVCGMCTLLYKWYIYDRSISKQNEE
CEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKRICLVIILIIVSFDQTSKLYINSLIDEGESIEITSFMKLVEVWNSGISFGMCSTLPHG
CHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
SFFFSACSILIIGILAYLIYKSNDKSIYLSFSLMIGGAIGNVIDRIYWGAVYDFIYFHIN
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
DWYWPAFNLADLSIVCGMCTLLYKWYIYDRSISKQNEE
CEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA