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The map label for this gene is nuoG [H]

Identifier: 189184499

GI number: 189184499

Start: 1624058

End: 1626097

Strand: Reverse

Name: nuoG [H]

Synonym: OTT_1592

Alternate gene names: 189184499

Gene position: 1626097-1624058 (Counterclockwise)

Preceding gene: 189184501

Following gene: 189184498

Centisome position: 80.94

GC content: 32.21

Gene sequence:

>2040_bases
ATGGTTAACCTGATAATTAATAATAAAAAAGTTAAAATTAAAGACGAAATAACAATTATTCAAGCTTGTGAGTTATTGAA
TATCGAAGTGCCAAGATTTTGCTATCACGAACGGTTGGCTATAGCTGGCAACTGTAGAATGTGCTTAGTTGAAATTGAAA
ATTCTCCTAAGTTAGTAGCTTCATGCGCAATGCCTATATCAGATGGTATGGTAATTCATACAAATTCTCCAAGAGTTGAA
AAAGCTCGAAAAAGTGTTATGGAATTTTTATTAATTAATCATCCACTAGATTGTCCGGTTTGTGATCAAGGTGGAGAATG
TGATTTACAGGATCAAGCATTTAAATATGGTAGTCAAGTTAGCCGCTTTAATGAAAATAAACGCATAGTTAAAGATAAAT
ATATGGGGCCATTAATTGCAACTCATATGACGCGCTGTATTCACTGTACTAGATGTATTAGATTTGCTCAAGATATAGCA
GGGATACCAGAAATAGGAGCAATTGGCAGAGGAGAAAATATGGAAGTGCAGACTTACTTAGAGCAAAGTATGAAATCTGA
ATTGTCTGGTAATGTAATTGATCTTTGCCCAGTTGGAGCATTGAATTCTAAGCCTTATGCTTATACAGCAAGAGCATGGG
AATTAACATGCACTGAATCAGTTGATGTATTTGATGCTATGGGATCGAATATTAAGATAAATTCTCGTGGTTTAGAGGTA
ATGCGAATTTTGCCATCTTATTGTGATGAAATTAATGAAGAATGGATATCTGATAAAAGTAGGTTTTCTTATGATGGACT
AAAATATCAGCGTCTTGATAGGCCATATATAAAAAGAAATGGTAGATTGCAAGAAGCAAGCTGGAATGAGGCTTTAGAAT
ATATAGCTGATAAGATGAAAGAAACTCCTGGAGAGAAAATGGCTGCTATTGCTGGTACTATGGCAGATTGTGAATCAATG
TTTGCTTTAAAATTATTGATGCAAAATTTTGGCTGTGGTAATTTTGACACTAATCAATTTAATTATAAATGGGATATTAG
CTCTCGAGGAAATTATTTATTTAATACCTCAATTGCTGGAGTTGATTTTTCAGATTTATGTTTGCTAGTTGGAGTTGATA
TGAATTTTTCTGCTCCAGTTCTTGGAGCAAGGTTAACAAGATTGCAACGTTCGAGGAAATTAAAAATATTGAATATTGGC
CCAGAAAATTATGAGCACAGGTTTAATGTAATTGATCTAGGAAATAACCCTAGTTTATTGGTTGATATTTTAAGTGGTAA
CCACCAAATTATAAATGAGATTAATAACGCTAAAAAACCGATGATGATTATTGGTGACTTGGCTTATGCCCGTGATGATG
GTTTTAAAGTGCTTGAATTGTGTCAAAATATTGCTTACAAGTATAATTTCATTCAACAAAATTGGAATGGGTATAATATT
TTACATAATCATGCTTCGACTGTTGGAGCTATTGATTTGGGATTTATTGCAGATACTAATAGTAAAAATGTAGCTGAAAT
TTTAAATAGCTGCGAACAAGGAGAAATATCATTAGTTTATTTGTTAGGTGTTGATGAGCTTGATACAAGTAAGCTAAGTA
ATGCTTTTGTTATTTATCAAGGACATCATGGTGATGTAGGGGCTAACTGTGCTGATATAGTATTGCCTGGAGCAGCATAT
ACTGAAAAAAATGCTATTTATGTTAATTTTGAGGGTAGGGCGCAATATGCTAGACAAGCAGTTGCTAAGGTAGGTTCAGC
TAAAGATGATTGGTTAATTATCAAAAATATATCTGATAAAGTAAAATCTAAATTTTACTTTAAAGACCTAGATGATTTAA
GAAGTCAAGCTGCTAAAGTTGCTAAATCATTAAGAAATATTGGTAATATACAAAAAAGCAGAGTAAAAAAGATTAAAAGT
GATATTATATTGAATACTGAAGAAGTATTTGCTTTAAAGAAACGTAATTTTTATATTACTGATGTAATTACTAGAGTATC
ACCAGTTATGGCAGAATGTACAAAAGTACAAAAGGGATAA

Upstream 100 bases:

>100_bases
AAGCGCGAATTAATTCACGAATTCCAAGAAATTAGTTTACTGCTGAAAGCTTAAGTTCTATAATCGATAAGTGGTTATTT
TATAACATATATTTATTTTA

Downstream 100 bases:

>100_bases
TATTAGAGTTAAAGTTAAATCTTGTACATTAAATAAAAAATAATAATTATGACTATATGACTATCTGTACAGATATAATT
GCAAATGGCTACGATTTAAA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIENSPKLVASCAMPISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GIPEIGAIGRGENMEVQTYLEQSMKSELSGNVIDLCPVGALNSKPYAYTARAWELTCTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKSRFSYDGLKYQRLDRPYIKRNGRLQEASWNEALEYIADKMKETPGEKMAAIAGTMADCESM
FALKLLMQNFGCGNFDTNQFNYKWDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRSRKLKILNIG
PENYEHRFNVIDLGNNPSLLVDILSGNHQIINEINNAKKPMMIIGDLAYARDDGFKVLELCQNIAYKYNFIQQNWNGYNI
LHNHASTVGAIDLGFIADTNSKNVAEILNSCEQGEISLVYLLGVDELDTSKLSNAFVIYQGHHGDVGANCADIVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLDDLRSQAAKVAKSLRNIGNIQKSRVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG

Sequences:

>Translated_679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIENSPKLVASCAMPISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GIPEIGAIGRGENMEVQTYLEQSMKSELSGNVIDLCPVGALNSKPYAYTARAWELTCTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKSRFSYDGLKYQRLDRPYIKRNGRLQEASWNEALEYIADKMKETPGEKMAAIAGTMADCESM
FALKLLMQNFGCGNFDTNQFNYKWDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRSRKLKILNIG
PENYEHRFNVIDLGNNPSLLVDILSGNHQIINEINNAKKPMMIIGDLAYARDDGFKVLELCQNIAYKYNFIQQNWNGYNI
LHNHASTVGAIDLGFIADTNSKNVAEILNSCEQGEISLVYLLGVDELDTSKLSNAFVIYQGHHGDVGANCADIVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLDDLRSQAAKVAKSLRNIGNIQKSRVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG
>Mature_679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIENSPKLVASCAMPISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GIPEIGAIGRGENMEVQTYLEQSMKSELSGNVIDLCPVGALNSKPYAYTARAWELTCTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKSRFSYDGLKYQRLDRPYIKRNGRLQEASWNEALEYIADKMKETPGEKMAAIAGTMADCESM
FALKLLMQNFGCGNFDTNQFNYKWDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRSRKLKILNIG
PENYEHRFNVIDLGNNPSLLVDILSGNHQIINEINNAKKPMMIIGDLAYARDDGFKVLELCQNIAYKYNFIQQNWNGYNI
LHNHASTVGAIDLGFIADTNSKNVAEILNSCEQGEISLVYLLGVDELDTSKLSNAFVIYQGHHGDVGANCADIVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLDDLRSQAAKVAKSLRNIGNIQKSRVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=697, Percent_Identity=46.1979913916786, Blast_Score=622, Evalue=1e-178,
Organism=Escherichia coli, GI145693161, Length=642, Percent_Identity=25.8566978193146, Blast_Score=206, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17565758, Length=697, Percent_Identity=44.3328550932568, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI32566231, Length=598, Percent_Identity=47.4916387959866, Blast_Score=545, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=58.1673306772908, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24640559, Length=691, Percent_Identity=43.5600578871201, Blast_Score=584, Evalue=1e-167,
Organism=Drosophila melanogaster, GI24640557, Length=691, Percent_Identity=43.5600578871201, Blast_Score=584, Evalue=1e-167,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 76283; Mature: 76283

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIENSPKLVA
CEEEEEECCEEEEECCEEHEEHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCCEEE
SCAMPISDGMVIHTNSPRVEKARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQV
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIAGIPEIGAIGRGENMEVQTYL
HHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
EQSMKSELSGNVIDLCPVGALNSKPYAYTARAWELTCTESVDVFDAMGSNIKINSRGLEV
HHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCEEECCCCHHH
MRILPSYCDEINEEWISDKSRFSYDGLKYQRLDRPYIKRNGRLQEASWNEALEYIADKMK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHH
ETPGEKMAAIAGTMADCESMFALKLLMQNFGCGNFDTNQFNYKWDISSRGNYLFNTSIAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECEECC
VDFSDLCLLVGVDMNFSAPVLGARLTRLQRSRKLKILNIGPENYEHRFNVIDLGNNPSLL
CCHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCEE
VDILSGNHQIINEINNAKKPMMIIGDLAYARDDGFKVLELCQNIAYKYNFIQQNWNGYNI
EEEECCCHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
LHNHASTVGAIDLGFIADTNSKNVAEILNSCEQGEISLVYLLGVDELDTSKLSNAFVIYQ
EECCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCEEEEEEEECCCCCHHHCCCEEEEEE
GHHGDVGANCADIVLPGAAYTEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDK
CCCCCCCCCHHHEEECCCCEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHH
VKSKFYFKDLDDLRSQAAKVAKSLRNIGNIQKSRVKKIKSDIILNTEEVFALKKRNFYIT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECHHHHHHHHCCCEEHH
DVITRVSPVMAECTKVQKG
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIENSPKLVA
CEEEEEECCEEEEECCEEHEEHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCCEEE
SCAMPISDGMVIHTNSPRVEKARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQV
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIAGIPEIGAIGRGENMEVQTYL
HHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
EQSMKSELSGNVIDLCPVGALNSKPYAYTARAWELTCTESVDVFDAMGSNIKINSRGLEV
HHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEEEEEECCCCHHHHHCCCCEEECCCCHHH
MRILPSYCDEINEEWISDKSRFSYDGLKYQRLDRPYIKRNGRLQEASWNEALEYIADKMK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHH
ETPGEKMAAIAGTMADCESMFALKLLMQNFGCGNFDTNQFNYKWDISSRGNYLFNTSIAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECEECC
VDFSDLCLLVGVDMNFSAPVLGARLTRLQRSRKLKILNIGPENYEHRFNVIDLGNNPSLL
CCHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCEE
VDILSGNHQIINEINNAKKPMMIIGDLAYARDDGFKVLELCQNIAYKYNFIQQNWNGYNI
EEEECCCHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
LHNHASTVGAIDLGFIADTNSKNVAEILNSCEQGEISLVYLLGVDELDTSKLSNAFVIYQ
EECCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCEEEEEEEECCCCCHHHCCCEEEEEE
GHHGDVGANCADIVLPGAAYTEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDK
CCCCCCCCCHHHEEECCCCEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHH
VKSKFYFKDLDDLRSQAAKVAKSLRNIGNIQKSRVKKIKSDIILNTEEVFALKKRNFYIT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECHHHHHHHHCCCEEHH
DVITRVSPVMAECTKVQKG
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA