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The map label for this gene is nuoH [H]

Identifier: 189184498

GI number: 189184498

Start: 1622958

End: 1624001

Strand: Reverse

Name: nuoH [H]

Synonym: OTT_1591

Alternate gene names: 189184498

Gene position: 1624001-1622958 (Counterclockwise)

Preceding gene: 189184499

Following gene: 189184497

Centisome position: 80.84

GC content: 31.7

Gene sequence:

>1044_bases
ATGACTATCTGTACAGATATAATTGCAAATGGCTACGATTTAAAAACACTAATTTATAATAGTGGAGTTGTTTCAATAAA
AGTTATAGCGTTAATTATTTGCTTGTTACTTGCAACAGCATATTTAACATTTGCTGAGAGAAAAGTCATTGCTTATATGC
AATTACGTGTTGGGCCTAGTTTGGCTGGCCCATTTGGATTGTTACAGCCGATAGCTGATGCTGTAAAATTAGTTTTTAAA
GAGCCTATTATACCAGCAAAAGCTGATAGGAAGTTGTTTATTATAGCTCCAATTATTACTTTTGTATTATCTTTATTAGG
TTGGTCTGTAATTCCAATTGACCATGATATCGTTCTTTCTAGAATTCATATAGGAGGAATATTATTTATATTAGCAGTAA
CTTCATTAGGAGTTTATGGAATTATAATTGCTGGTTGGGCAAGTAATTCTAAGTATGCTTTTTTAGGTGCTGTAAGGTCT
GCAGCGCAAATGATTTCATATGAATTAGCAATGGCACTAAGTATAGTTGCAGTACTTATTGTGACTGGAGAAATGGATTT
GATTCAAATTGTTGAAGCGCAAAAAACTAGGCCTATATGGTTAACAATAATGATGCTACCATTAGCAGTTATTTATTTTA
TATCAATATTAGCTAAAACTAATAGGCTGCCATTTGATCTTCCAGAGGCTGAATCTGAGCTAGTTGCAGGATATAATGTT
GAATATTCTTCTATGGCTTTTGCTATGTTTTTTCTTGGAGAATATGCTAACATGATATTGGGTAGTAGCTTAATGACCAT
CATGTTTTTAGGAGGATACTTGCCTCCATTTAATTTAGAGATATTAACTTTCATTCCAGGTTATATATGGTTTATATTAA
AAGTATCTATGGTATTATTCTGTTTTTTATGGATACGAGCAACGTTGCCACGATATAGATATGATCAATTAATGTATTTG
GGATTGAAAGTATTTTTGCCGATTGTATTAGCTTGGATAATAGTAGTATCAGCTATTTTAGTATATAGTAATAACTTACC
ATAG

Upstream 100 bases:

>100_bases
TATCACCAGTTATGGCAGAATGTACAAAAGTACAAAAGGGATAATATTAGAGTTAAAGTTAAATCTTGTACATTAAATAA
AAAATAATAATTATGACTAT

Downstream 100 bases:

>100_bases
CACTAGAAACTGCGCTAGACAAATAATTGGATTTATAATGTAGAGAATCGAAAATGAAGATAACTAATTTTACTAAATCT
TTTCTTTTGTATGAAATTAT

Product: NADH dehydrogenase I chain H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTICTDIIANGYDLKTLIYNSGVVSIKVIALIICLLLATAYLTFAERKVIAYMQLRVGPSLAGPFGLLQPIADAVKLVFK
EPIIPAKADRKLFIIAPIITFVLSLLGWSVIPIDHDIVLSRIHIGGILFILAVTSLGVYGIIIAGWASNSKYAFLGAVRS
AAQMISYELAMALSIVAVLIVTGEMDLIQIVEAQKTRPIWLTIMMLPLAVIYFISILAKTNRLPFDLPEAESELVAGYNV
EYSSMAFAMFFLGEYANMILGSSLMTIMFLGGYLPPFNLEILTFIPGYIWFILKVSMVLFCFLWIRATLPRYRYDQLMYL
GLKVFLPIVLAWIIVVSAILVYSNNLP

Sequences:

>Translated_347_residues
MTICTDIIANGYDLKTLIYNSGVVSIKVIALIICLLLATAYLTFAERKVIAYMQLRVGPSLAGPFGLLQPIADAVKLVFK
EPIIPAKADRKLFIIAPIITFVLSLLGWSVIPIDHDIVLSRIHIGGILFILAVTSLGVYGIIIAGWASNSKYAFLGAVRS
AAQMISYELAMALSIVAVLIVTGEMDLIQIVEAQKTRPIWLTIMMLPLAVIYFISILAKTNRLPFDLPEAESELVAGYNV
EYSSMAFAMFFLGEYANMILGSSLMTIMFLGGYLPPFNLEILTFIPGYIWFILKVSMVLFCFLWIRATLPRYRYDQLMYL
GLKVFLPIVLAWIIVVSAILVYSNNLP
>Mature_346_residues
TICTDIIANGYDLKTLIYNSGVVSIKVIALIICLLLATAYLTFAERKVIAYMQLRVGPSLAGPFGLLQPIADAVKLVFKE
PIIPAKADRKLFIIAPIITFVLSLLGWSVIPIDHDIVLSRIHIGGILFILAVTSLGVYGIIIAGWASNSKYAFLGAVRSA
AQMISYELAMALSIVAVLIVTGEMDLIQIVEAQKTRPIWLTIMMLPLAVIYFISILAKTNRLPFDLPEAESELVAGYNVE
YSSMAFAMFFLGEYANMILGSSLMTIMFLGGYLPPFNLEILTFIPGYIWFILKVSMVLFCFLWIRATLPRYRYDQLMYLG
LKVFLPIVLAWIIVVSAILVYSNNLP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=294, Percent_Identity=45.578231292517, Blast_Score=253, Evalue=1e-67,
Organism=Escherichia coli, GI1788618, Length=318, Percent_Identity=38.3647798742138, Blast_Score=238, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38513; Mature: 38382

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTICTDIIANGYDLKTLIYNSGVVSIKVIALIICLLLATAYLTFAERKVIAYMQLRVGPS
CCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LAGPFGLLQPIADAVKLVFKEPIIPAKADRKLFIIAPIITFVLSLLGWSVIPIDHDIVLS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHCCEEECCCHHHHHH
RIHIGGILFILAVTSLGVYGIIIAGWASNSKYAFLGAVRSAAQMISYELAMALSIVAVLI
HHHHHHHHHHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGEMDLIQIVEAQKTRPIWLTIMMLPLAVIYFISILAKTNRLPFDLPEAESELVAGYNV
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC
EYSSMAFAMFFLGEYANMILGSSLMTIMFLGGYLPPFNLEILTFIPGYIWFILKVSMVLF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CFLWIRATLPRYRYDQLMYLGLKVFLPIVLAWIIVVSAILVYSNNLP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TICTDIIANGYDLKTLIYNSGVVSIKVIALIICLLLATAYLTFAERKVIAYMQLRVGPS
CCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LAGPFGLLQPIADAVKLVFKEPIIPAKADRKLFIIAPIITFVLSLLGWSVIPIDHDIVLS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHCCEEECCCHHHHHH
RIHIGGILFILAVTSLGVYGIIIAGWASNSKYAFLGAVRSAAQMISYELAMALSIVAVLI
HHHHHHHHHHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGEMDLIQIVEAQKTRPIWLTIMMLPLAVIYFISILAKTNRLPFDLPEAESELVAGYNV
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCC
EYSSMAFAMFFLGEYANMILGSSLMTIMFLGGYLPPFNLEILTFIPGYIWFILKVSMVLF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CFLWIRATLPRYRYDQLMYLGLKVFLPIVLAWIIVVSAILVYSNNLP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA