Definition Treponema pallidum subsp. pallidum SS14, complete genome.
Accession NC_010741
Length 1,139,457

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The map label for this gene is yebA [H]

Identifier: 189026088

GI number: 189026088

Start: 943137

End: 944777

Strand: Reverse

Name: yebA [H]

Synonym: TPASS_0864

Alternate gene names: 189026088

Gene position: 944777-943137 (Counterclockwise)

Preceding gene: 189026089

Following gene: 189026086

Centisome position: 82.91

GC content: 55.58

Gene sequence:

>1641_bases
TTGCGCCCGGCGAGGTGTGTTCTTTATACGGGGCGTGCGCCGTGCGGTTCAAAAACAAGTGGCACGCTGCTGGGGACTCC
GCCGCCTGTGGCGCTGCAGGCGAAATGCTCAACGCCTGGAATAAATGTTCCGATACCGCCCGTTATGGACGTGATTACGT
ACACGGGTGCGGACTTAGTTCCGGATCATGCGCGGGGATGTGAGCCGTTCAGCGTGTGTCCGAGCCCTGCAGAAGTGCGC
CGCGCAGTTCTTTCAAGTAGTGCGTTTTCCGATAGCGGGGGTGCGCGCGCTCGTACGCGTAACCGTCTTGTTCCCCGTTT
TCCCCTTGAGGAAGAGATAATTTCGTTTCATGAAAGTCCTGATACCCTCGATATTCCTGAGTCAGGCAGCGGAGTCAGTG
GGAGACTCGGAGGAGGGCGGGGCTTACGCGCGCGCTACGCAAAATGGAGCACACGTGCAGAAGCGCGTTTGATACGTGCG
CAGGCGCTCAACGCTTCGGGGTTGCTCAGCAGTATTTCAAACCGTTCTGTTCGGGTGAGCCGCAGGCGGGGTATAGGGGG
GATGCGTTTTTTCCGGAGAGAAAAGAGTGCACGCACGCCGCTTGCGCGCACCGCGGTGCCTCGTTTTTCTTTTCCTTCCT
TTTCGGTGCCTGTACGTTCTTTGCAGGATGCTTCTTGTGTGCCGTTGTGTGCGGCGTTGGCTTGCGCGCTGCTCTTTGTG
CTCATGGTGCTGTGTATCCCGTGGGCGGTGCACGTTACCGGTGGCAGAAGGCTTGCGCTGGTGCGTTTTGAAACAGACAG
CACGCTGGCGCATGCGCTGCGTCGTGGGGTTTTTCGTGCAGAGGAGGTAGAAACGCGCGAGGGCGGCGCGAACGCTGCCG
CGCTTGCAGAGGCGTTGGATACGCAGCTTGCGACGGTGAGCTACCGCACGTACACCGTACGTAAGGGAGATACTATTAGT
GCCATTGCGCTGCGCGCAGGACTCAAGCATATGGGGACGCTGCTGTCGGTGAACGGAATTTCAAACGCGCGCAGACTATC
GGTAGGGGATCAAATTACTATTCCGTCCATGGATGGACTCATGCACACGGTACAAAAGGGGCAGTCGCTTAGTGCAATTG
CCAGTCTCTTTCGTTTGCCCCTGAATACGTTGCTGGATGCGAATGATTTAGTCAGTCGTGCATTAACAGTTGGACAGCGT
TTGTTTATTCCGGGTGCAAAATTATCTGCTTTTGATTTGAGGAAGGTGTTGGGGGAGTTATTCATGTATCCAATTCGCGG
GCGGCGCACCTCTGGGTTTGGGTACCGCTCAGATCCCTTTTCAGGCAAAAGGAGCTTTCACAATGGGATTGACCTAGCCG
CACCCTATGGGACGCAGGTGAAAGCAACGCTCGATGGGAAAGTGGCAGAAATTGGATATAGCAGAATTTACGGGAATTAC
CTGATCATCGTGCACGGCGGTGGATACCAAACCATGTATGGGCATTTAAGTTCGGTGATGGTAGGGCGTGGGGCGCGGGT
AGTCCAGGGGACGACCATTGGGCGCGTGGGGGCTAGCGGTCGGGCAACTGGTCCGCATTTGCATTTTTCAGTATTTAAGA
ACGGGTCGGTGGTAAATCCGTTAAAAATTTTGACAAAATAA

Upstream 100 bases:

>100_bases
TATCGAGCGTGCAACGAAGCTTTTGCAATTAAACCGGCAGGTTTACGATTTTCATTTTCTTCACTGAACTCTGCTTTATC
GGGAAAGACACCCTCGGCGG

Downstream 100 bases:

>100_bases
GGGGTTGTGTGCGGCGCTTGAGTGCTTCCTGTGCGTGTACCCTTTCTGTGTGGAGCGGTCATAGTTTTTGCAGCAGGGTA
CGGAAAAGCGTTAAGACCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MRPARCVLYTGRAPCGSKTSGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLVPDHARGCEPFSVCPSPAEVR
RAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESPDTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRA
QALNASGLLSSISNRSVRVSRRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALDTQLATVSYRTYTVRKGDTIS
AIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGLMHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQR
LFIPGAKLSAFDLRKVLGELFMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNPLKILTK

Sequences:

>Translated_546_residues
MRPARCVLYTGRAPCGSKTSGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLVPDHARGCEPFSVCPSPAEVR
RAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESPDTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRA
QALNASGLLSSISNRSVRVSRRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALDTQLATVSYRTYTVRKGDTIS
AIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGLMHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQR
LFIPGAKLSAFDLRKVLGELFMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNPLKILTK
>Mature_546_residues
MRPARCVLYTGRAPCGSKTSGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLVPDHARGCEPFSVCPSPAEVR
RAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESPDTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRA
QALNASGLLSSISNRSVRVSRRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALDTQLATVSYRTYTVRKGDTIS
AIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGLMHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQR
LFIPGAKLSAFDLRKVLGELFMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNPLKILTK

Specific function: Could be involved in cell wall degradation or formation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

Organism=Escherichia coli, GI87081989, Length=106, Percent_Identity=42.4528301886792, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI87082297, Length=123, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082174, Length=253, Percent_Identity=26.4822134387352, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789099, Length=125, Percent_Identity=32, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR013731
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF08525 OapA_N; PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 58515; Mature: 58515

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPARCVLYTGRAPCGSKTSGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLV
CCCCEEEEEECCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCC
PDHARGCEPFSVCPSPAEVRRAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESP
CCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHCCCC
DTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRAQALNASGLLSSISNRSVRVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEH
RRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
HHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALD
HHHHHCCCEEEECCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
TQLATVSYRTYTVRKGDTISAIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGL
HHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCEEECCCHHHH
MHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQRLFIPGAKLSAFDLRKVLGEL
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHH
FMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
HHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCEEEEEECCCHHHHHHHEEECCE
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNP
EEEEECCCCHHHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCCCEEEEEEECCCCCCCH
LKILTK
HHHHCC
>Mature Secondary Structure
MRPARCVLYTGRAPCGSKTSGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLV
CCCCEEEEEECCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCC
PDHARGCEPFSVCPSPAEVRRAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESP
CCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHCCCC
DTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRAQALNASGLLSSISNRSVRVS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEH
RRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
HHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALD
HHHHHCCCEEEECCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
TQLATVSYRTYTVRKGDTISAIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGL
HHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCEEECCCHHHH
MHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQRLFIPGAKLSAFDLRKVLGEL
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHH
FMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
HHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCEEEEEECCCHHHHHHHEEECCE
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNP
EEEEECCCCHHHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCCCEEEEEEECCCCCCCH
LKILTK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]