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The map label for this gene is nadD

Identifier: 189025966

GI number: 189025966

Start: 807602

End: 808216

Strand: Reverse

Name: nadD

Synonym: TPASS_0741

Alternate gene names: 189025966

Gene position: 808216-807602 (Counterclockwise)

Preceding gene: 189025967

Following gene: 189025965

Centisome position: 70.93

GC content: 55.28

Gene sequence:

>615_bases
ATGAAGTTAGCCCTGTTTGGCGGTTCGTACGATCCTGTTCATCTGGGCCACTTGCTCTTGGCTGATGCAGTACACCGGCA
CGCCGGGTATGACCGCGTGCTGTTTGTGCCTACCTTCGTTTCCCCCTTCAAAGAAAAGGAAGGAAGTGCAAGTGCGCACG
ATCGGGTGCGGATGCTCCATTTAGCAATTGGGACAACGCCGTATTTTTCTGTTGAAGAGTGTGAGATTAGGCGTGGGGGT
ATTTCGTATACTGCCGAGACGGTGCAGCATGTGCGGGAAAAGTATGGCGCACAGCTTGAGGGCAAGCTCGCGCTGGTATT
GGGGGAAGATGCAGCGCGCAGTGTACCGCACTGGCACGCGTTCGATTCGTGGAGTACACACGTTGATTTTGTCGTGGGTG
CGCGCCCTGTGACGTCAGGCGATGGGGGGAACGTAGAACGCGCCACACGCACTCTACAATCGTTTCCCTTCCCATGGGTT
TCGGCGGAGAATGTGGCGCTTCCTATTTCGTCAACGTACATACGCACCGCAATTCAACGGGGGCGTAGTTGGGGTTATCT
TGTACCTTCCCCAGTTCGTGAGTATATTATCGCGCGTGGACTCTACCGGTCGTGA

Upstream 100 bases:

>100_bases
CTCCCAGTTTTATGTACGCTCAGCTTGAGGATCCGGTGTGTCAGGTGCGTGATGATTTTGGGGCAACGGTGAGCTTGAGC
AGAAAACGAAAAGTGCGCGG

Downstream 100 bases:

>100_bases
GCCTCTGCCTTCTTTCTCCGGAGTGGACGATTCTTCCTGTTCTTCTCGTTTTCTTTCTTTCCTTGGACAGGCGCAGATGC
CAGCGTTCTCTTTTGTGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLHLAIGTTPYFSVEECEIRRGG
ISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHAFDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWV
SAENVALPISSTYIRTAIQRGRSWGYLVPSPVREYIIARGLYRS

Sequences:

>Translated_204_residues
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLHLAIGTTPYFSVEECEIRRGG
ISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHAFDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWV
SAENVALPISSTYIRTAIQRGRSWGYLVPSPVREYIIARGLYRS
>Mature_204_residues
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLHLAIGTTPYFSVEECEIRRGG
ISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHAFDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWV
SAENVALPISSTYIRTAIQRGRSWGYLVPSPVREYIIARGLYRS

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=220, Percent_Identity=32.2727272727273, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_TREPA (O83723)

Other databases:

- EMBL:   AE000520
- PIR:   B71286
- RefSeq:   NP_219178.1
- ProteinModelPortal:   O83723
- IntAct:   O83723
- GeneID:   2611091
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0741
- NMPDR:   fig|243276.1.peg.737
- TIGR:   TP_0741
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- ProtClustDB:   CLSK2300288
- BioCyc:   TPAL243276:TP_0741-MONOMER
- BRENDA:   2.7.7.18
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 22650; Mature: 22650

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLH
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHCHHHHCCCCCCHHHHHEEEE
LAIGTTPYFSVEECEIRRGGISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHA
EEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCC
FDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWVSAENVALPISSTYIRTAIQR
CCCCCCCEEEEEECCEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHC
GRSWGYLVPSPVREYIIARGLYRS
CCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLH
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHCHHHHCCCCCCHHHHHEEEE
LAIGTTPYFSVEECEIRRGGISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHA
EEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCC
FDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWVSAENVALPISSTYIRTAIQR
CCCCCCCEEEEEECCEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHC
GRSWGYLVPSPVREYIIARGLYRS
CCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876