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The map label for this gene is deoD

Identifier: 189025959

GI number: 189025959

Start: 800532

End: 801233

Strand: Reverse

Name: deoD

Synonym: TPASS_0734

Alternate gene names: 189025959

Gene position: 801233-800532 (Counterclockwise)

Preceding gene: 189025960

Following gene: 189025957

Centisome position: 70.32

GC content: 57.41

Gene sequence:

>702_bases
ATGAGTATTCACCTTGGAGCAAAGGGAGAGGATATTGCGCCGCGCGTGCTGTTGCCCGGTGACCCGCTGCGTGCGCGTTT
TGTGGCGGAGCGTTTTTTTCACAATGCGTATTGCTACAATGAGGTGCGTGGCATGCTCGGGTTTACGGGAACCTACAAGG
GGGTGCGCGTGTCGGTGCAGGGGACAGGTATGGGGCTGCCGTCGCACTCAATTTACGTAACGGAGCTGTTTCAAGATTAT
GGGGTGCAAAAGGCAATCCGCGTGGGGACTGCCGGTGGATTGCAGGAGGAAGTGGCGCTCAAATCGGTGGTGTGTGCGCT
GGGTGCGGCAACGGATTCTGCAATAAACGCGCGCAGGTTTAGCGGCATGCACTTTGCGCCCACGGCAAGCTGGTCGCTCC
TGCGCACGGCAGTGTCGGTTGCTGATGAAATGGGCACGGGGGTGCAGGTGGGGAATGTAATTTCCTCTGACGTCTTTTAC
GATGAATCAGGAAGCTGGCGCCTGTGGGCCCGGTATGGGGTGTTAGCGGTGGAAATGGAAACGGCGGAGCTGTACACGCT
TGCTGCAAAGTTCAGACGCGAGGCGCTGAGCATTCTGACTATCTCTGACCACCTGGTAACCGGCGCGGTAACTAGCGCGC
AGGAGCGGGAGCGCTCCTTTACCCAAATGATAGAAATTGCGCTTGAAGCCATTATCCAGTAG

Upstream 100 bases:

>100_bases
CCTTGCGCAAAAAGCGTAACGGGTGCTGCATGCGCTGAGCGTACACGCGCGAGGTTACCGAAACGTGTGGGTCTAGGCCC
CACGAAGGGAGGGAGTGACG

Downstream 100 bases:

>100_bases
GGACGCGCGCGCCACCTGCCCCGGCGGCGGGGCTAAAAGTGATAGCGCACCCCAAAGTCAATGGTGGCAAGGCCCACGGC
TCTGCACTTGTCGGGGGAGC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQGTGMGLPSHSIYVTELFQDY
GVQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFY
DESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ

Sequences:

>Translated_233_residues
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQGTGMGLPSHSIYVTELFQDY
GVQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFY
DESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
>Mature_232_residues
SIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQGTGMGLPSHSIYVTELFQDYG
VQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFYD
ESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=48.695652173913, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1790265, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_TREPA (O83716)

Other databases:

- EMBL:   AE000520
- PIR:   C71288
- RefSeq:   NP_219171.1
- ProteinModelPortal:   O83716
- SMR:   O83716
- GeneID:   2611065
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0734
- NMPDR:   fig|243276.1.peg.730
- TIGR:   TP_0734
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- ProtClustDB:   CLSK218837
- BioCyc:   TPAL243276:TP_0734-MONOMER
- BRENDA:   2.4.2.1
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25318; Mature: 25187

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQ
CEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GTGMGLPSHSIYVTELFQDYGVQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRF
ECCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
SGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFYDESGSWRLWARYGVLAVEME
CCCEECCCCHHHHHHHHHHHHHHHCCCEEECCCHHCCEEECCCCCEEEEEECCEEEEEEC
TAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
HHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQ
EEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GTGMGLPSHSIYVTELFQDYGVQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRF
ECCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
SGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFYDESGSWRLWARYGVLAVEME
CCCEECCCCHHHHHHHHHHHHHHHCCCEEECCCHHCCEEECCCCCEEEEEECCEEEEEEC
TAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
HHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876