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The map label for this gene is zraS [C]

Identifier: 188586455

GI number: 188586455

Start: 1915914

End: 1917362

Strand: Reverse

Name: zraS [C]

Synonym: Nther_1840

Alternate gene names: 188586455

Gene position: 1917362-1915914 (Counterclockwise)

Preceding gene: 188586456

Following gene: 188586454

Centisome position: 60.57

GC content: 34.37

Gene sequence:

>1449_bases
TTGGTTGATAATAGACCAATAGCAACTTATGTAAGCCAAAATATTAAAAATATTCTCGGTTATGATCCCGACAAATTTTT
GGGAAAAATGGACTATTTTTGGAAAAAATTAATCCACCCCGAAGACATAGACAATATAAAAATAGTAGGTCAGATCGGTG
AAGAAATTATTAATGAATATAGAGTGAAAGATCGTAGAGGTGAATATCATTGGATTTACTCTCAACATAAAATTATGGAA
AATGATGAATGTGGGTTAGAGGCAATCGGATCTTTTTGGGACATTACCGAGCGCAAACAGGCTGAAGAACAACAGCGGAT
GATAGATAAAATTGACACAACTGCATTAATGGCAGGTGGGATTGCCCATGACTTTAACAATATCCTTACTATCTGTAAAG
GGAATGTATCTTTAGCTAAATTTTATTTAAAATCATTAGGAGACAAACCTTTAAAAACAATCAAGTTGTTAGAAGATGCC
GAACAAAGCTTTGATCAGGCGGGATATTTAACTCATCAACTATTGACATTGTCTAAAGGTGATTCACCTGTATTAAAAGC
AACCAGTCTAAAAAATTTATTGACTGAGTCGGTTTATTTTGCATTAAGAGGATCAAAAGTAGACTGTCAATGGGAAATAG
AAGAGAATTTATATCCTGTGGAAGTTGACGAAGGACAAATAAATCAAGTAATCAATAACCTAGTTATCAATGCTATTCAA
TCTATGCCTGAAGGAGGCACCTTAACTGTCAGAGCACAGAATATTACTTTCCATGGACAGAATCCCAAGATTCCCTTAGA
AAAAGGAGCTTATGTTAAAGTATCATTTGCAGATCAGGGGTGCGGGATATCAGATGAAGTTATTGAAAAAATATTTGATC
CATATTTTTCAACTAAGAAACATGGTCGTGGTTTAGGCTTGGCTACTAGTTTTTCAATAATAAATAAGCATGGAGGTTAC
ATAACTGTAGATTCGAAAGAAGGAGTAGGAACAACTTTTCATATTTATTTACGAGCTTCTACTAAAAAGATGGTTAAAGA
GGAAAGCAATATCCCCAAGGAGATTTATAATAGTATGCAAACAAATAAAAAAGTTCTCATAATGGATGATAAAGATAAAG
TACGGCGGGTTTTTTACGAATTACTAACATCTATGGGATTTGATGTAACATGTACACGAAATGGGGAAGAAGCTGTAAAC
ATATATAAGCAAGCAAATAAATCATTTGATATTGTCTTTTTGGACCTGACAGTTCCTGGTGGCATGGGTGGTAAGGAAAC
TATTAAAAAACTTAAGGCCATGGACCCAAGTGTAACTGCAATAGCCGCTAGTGGTTACAGTGAAGATCCGATACATTTAA
ATTATTCAGATTATGGTTTTGCGGCCGCCATAACCAAACCCTTCAGTATGGCAGAATTACATAAAGTATTACATTCAGTG
ATATGTTAA

Upstream 100 bases:

>100_bases
ACATTTCAGATTTAAAAGAAACGGAGAAAAGACTTCGAAAGAGTGAGCAGCGCTTTATACTCTTATTTCTCAAACTCCAG
CAGTTATTTATTCATTTAAA

Downstream 100 bases:

>100_bases
AATTGAATTTGATAAACTATCTTAACATAAGGAGTGATAGACAGTTATGCAAGTCGGTGACAGAAATGAAATAGTCAAGG
AAGTAAGTAAAGAATTTTCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MVDNRPIATYVSQNIKNILGYDPDKFLGKMDYFWKKLIHPEDIDNIKIVGQIGEEIINEYRVKDRRGEYHWIYSQHKIME
NDECGLEAIGSFWDITERKQAEEQQRMIDKIDTTALMAGGIAHDFNNILTICKGNVSLAKFYLKSLGDKPLKTIKLLEDA
EQSFDQAGYLTHQLLTLSKGDSPVLKATSLKNLLTESVYFALRGSKVDCQWEIEENLYPVEVDEGQINQVINNLVINAIQ
SMPEGGTLTVRAQNITFHGQNPKIPLEKGAYVKVSFADQGCGISDEVIEKIFDPYFSTKKHGRGLGLATSFSIINKHGGY
ITVDSKEGVGTTFHIYLRASTKKMVKEESNIPKEIYNSMQTNKKVLIMDDKDKVRRVFYELLTSMGFDVTCTRNGEEAVN
IYKQANKSFDIVFLDLTVPGGMGGKETIKKLKAMDPSVTAIAASGYSEDPIHLNYSDYGFAAAITKPFSMAELHKVLHSV
IC

Sequences:

>Translated_482_residues
MVDNRPIATYVSQNIKNILGYDPDKFLGKMDYFWKKLIHPEDIDNIKIVGQIGEEIINEYRVKDRRGEYHWIYSQHKIME
NDECGLEAIGSFWDITERKQAEEQQRMIDKIDTTALMAGGIAHDFNNILTICKGNVSLAKFYLKSLGDKPLKTIKLLEDA
EQSFDQAGYLTHQLLTLSKGDSPVLKATSLKNLLTESVYFALRGSKVDCQWEIEENLYPVEVDEGQINQVINNLVINAIQ
SMPEGGTLTVRAQNITFHGQNPKIPLEKGAYVKVSFADQGCGISDEVIEKIFDPYFSTKKHGRGLGLATSFSIINKHGGY
ITVDSKEGVGTTFHIYLRASTKKMVKEESNIPKEIYNSMQTNKKVLIMDDKDKVRRVFYELLTSMGFDVTCTRNGEEAVN
IYKQANKSFDIVFLDLTVPGGMGGKETIKKLKAMDPSVTAIAASGYSEDPIHLNYSDYGFAAAITKPFSMAELHKVLHSV
IC
>Mature_482_residues
MVDNRPIATYVSQNIKNILGYDPDKFLGKMDYFWKKLIHPEDIDNIKIVGQIGEEIINEYRVKDRRGEYHWIYSQHKIME
NDECGLEAIGSFWDITERKQAEEQQRMIDKIDTTALMAGGIAHDFNNILTICKGNVSLAKFYLKSLGDKPLKTIKLLEDA
EQSFDQAGYLTHQLLTLSKGDSPVLKATSLKNLLTESVYFALRGSKVDCQWEIEENLYPVEVDEGQINQVINNLVINAIQ
SMPEGGTLTVRAQNITFHGQNPKIPLEKGAYVKVSFADQGCGISDEVIEKIFDPYFSTKKHGRGLGLATSFSIINKHGGY
ITVDSKEGVGTTFHIYLRASTKKMVKEESNIPKEIYNSMQTNKKVLIMDDKDKVRRVFYELLTSMGFDVTCTRNGEEAVN
IYKQANKSFDIVFLDLTVPGGMGGKETIKKLKAMDPSVTAIAASGYSEDPIHLNYSDYGFAAAITKPFSMAELHKVLHSV
IC

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=29.7619047619048, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=31.1284046692607, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=419, Percent_Identity=25.5369928400955, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=25.3846153846154, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=296, Percent_Identity=25.3378378378378, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786600, Length=261, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54177; Mature: 54177

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDNRPIATYVSQNIKNILGYDPDKFLGKMDYFWKKLIHPEDIDNIKIVGQIGEEIINEY
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
RVKDRRGEYHWIYSQHKIMENDECGLEAIGSFWDITERKQAEEQQRMIDKIDTTALMAGG
HHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IAHDFNNILTICKGNVSLAKFYLKSLGDKPLKTIKLLEDAEQSFDQAGYLTHQLLTLSKG
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
DSPVLKATSLKNLLTESVYFALRGSKVDCQWEIEENLYPVEVDEGQINQVINNLVINAIQ
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHH
SMPEGGTLTVRAQNITFHGQNPKIPLEKGAYVKVSFADQGCGISDEVIEKIFDPYFSTKK
HCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
HGRGLGLATSFSIINKHGGYITVDSKEGVGTTFHIYLRASTKKMVKEESNIPKEIYNSMQ
CCCCCCEEHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECHHHHHHHHCCCCHHHHHHHH
TNKKVLIMDDKDKVRRVFYELLTSMGFDVTCTRNGEEAVNIYKQANKSFDIVFLDLTVPG
CCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEEECCC
GMGGKETIKKLKAMDPSVTAIAASGYSEDPIHLNYSDYGFAAAITKPFSMAELHKVLHSV
CCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEEHHCCCCCHHHHHHHHHHH
IC
CC
>Mature Secondary Structure
MVDNRPIATYVSQNIKNILGYDPDKFLGKMDYFWKKLIHPEDIDNIKIVGQIGEEIINEY
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
RVKDRRGEYHWIYSQHKIMENDECGLEAIGSFWDITERKQAEEQQRMIDKIDTTALMAGG
HHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IAHDFNNILTICKGNVSLAKFYLKSLGDKPLKTIKLLEDAEQSFDQAGYLTHQLLTLSKG
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
DSPVLKATSLKNLLTESVYFALRGSKVDCQWEIEENLYPVEVDEGQINQVINNLVINAIQ
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHH
SMPEGGTLTVRAQNITFHGQNPKIPLEKGAYVKVSFADQGCGISDEVIEKIFDPYFSTKK
HCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
HGRGLGLATSFSIINKHGGYITVDSKEGVGTTFHIYLRASTKKMVKEESNIPKEIYNSMQ
CCCCCCEEHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECHHHHHHHHCCCCHHHHHHHH
TNKKVLIMDDKDKVRRVFYELLTSMGFDVTCTRNGEEAVNIYKQANKSFDIVFLDLTVPG
CCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEEECCC
GMGGKETIKKLKAMDPSVTAIAASGYSEDPIHLNYSDYGFAAAITKPFSMAELHKVLHSV
CCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCEEEHHCCCCCHHHHHHHHHHH
IC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA