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The map label for this gene is 188586389

Identifier: 188586389

GI number: 188586389

Start: 1840992

End: 1842101

Strand: Reverse

Name: 188586389

Synonym: Nther_1774

Alternate gene names: NA

Gene position: 1842101-1840992 (Counterclockwise)

Preceding gene: 188586390

Following gene: 188586388

Centisome position: 58.19

GC content: 36.13

Gene sequence:

>1110_bases
GTGGCAGTCTTAGGGGGCGGTCCAGCGGGGTTAGCCGCATCTATCCAAGGGGCCCAACAAGGATTGAGTGTAACTTTATT
CGAAAAAAATAAGGTTGGAGAAAACATTAAATGTGCCGAAGGTTTTTATGATTCAATGAAACTATTCGGCCCTCCTTCTC
ATGGAGCATTATTTAAAGTTGATTGTCTACATATAAAAGTTAAAGATGAATACAAAGTAGATTGTTCTAATGTAAATCTT
TGGATGATTGATCGCCAAACTTGGCAAAAAGGGTTGAAGGAAGAGGCCATGGCATTAGGGGTAGATGTCAAAGAGAATTG
TCCCGTTAATCCTACAGATTTGGTAAGTATAAGCCAAAACTATGATTGGGTGATTGATTGTACAGGGATTCCTTCTACAA
CATCTATTTCTAAAGGTTTTAGCCATGTTTACAAAAACTATTGGGCTTACGCACATCAAATAACATTATTTGGTAATTTC
CAAAATCAGCTAGGTGAGTTGAAAGTAGGTGTAAGTCCTGATTATTTAGGTTATTACTGGATATTTCCTAAATCTAAAGA
TTTTGCCAATGTTGGCCTGGGAATTTTTCCTCAAAATAATAAGTACCCAGAGACTTTGAAAAAACGTCTAAAGCGAGAAT
TACATAATATTATTCATAGAGAAGGACTGCAAAACTGTAAAAAAGTGCGTAAAACTGGTGGTGTTATACCCACTAAACCC
CTAGATGAACTAGTATTTGATAATATAATTTTAGCTGGAGATAGTGGTGGCTTTTCTTCCCCCCTTCACGGAGGGGGAAT
AGACCTGGCCTTATTTACTGGAAAAGAAGCTATCAATGCAATTAATGAGGGAGAAATAGATAATTATCGTCAGAGATTAT
TAGATAAAGCGGGAGCGAAACTAGAGATAGAGCAGAAAATTTTCGATTTGTGGGAACAGATTGGATACGAAAATTTAGAC
AGGCTATTACGATTAATTCTAAAAAGAGAAGCTGTTTTTGAATTACCTAGATTATTTCAGTTTAGGGATTTATTGATTAG
TGAACGTCAGACCATAACTGCTTTTTATGACGGTTTTTTTCAAGGTAATTGGGACAGGATTTCTTATTAA

Upstream 100 bases:

>100_bases
CGTAAAATTCTGGGTTGAGTTTTAAAGCGGTTTTCGATATTATAAATTTAAGTCCGATTAGTTAATAGAAAGTGGTGATA
CTTTGGGAGCAGGAGTTACA

Downstream 100 bases:

>100_bases
TTAAAGACATCACAATATATTAGATTTTTTTAAATTATTATTGTTGGAAAAGTGCATATTATTATAAGTTAAAAAGTGAT
CGGCTTGCCATTAAGGTAGG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: DGGGPL reductase 2; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 2; Geranylgeranyl reductase 2; GGR 2 [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAVLGGGPAGLAASIQGAQQGLSVTLFEKNKVGENIKCAEGFYDSMKLFGPPSHGALFKVDCLHIKVKDEYKVDCSNVNL
WMIDRQTWQKGLKEEAMALGVDVKENCPVNPTDLVSISQNYDWVIDCTGIPSTTSISKGFSHVYKNYWAYAHQITLFGNF
QNQLGELKVGVSPDYLGYYWIFPKSKDFANVGLGIFPQNNKYPETLKKRLKRELHNIIHREGLQNCKKVRKTGGVIPTKP
LDELVFDNIILAGDSGGFSSPLHGGGIDLALFTGKEAINAINEGEIDNYRQRLLDKAGAKLEIEQKIFDLWEQIGYENLD
RLLRLILKREAVFELPRLFQFRDLLISERQTITAFYDGFFQGNWDRISY

Sequences:

>Translated_369_residues
MAVLGGGPAGLAASIQGAQQGLSVTLFEKNKVGENIKCAEGFYDSMKLFGPPSHGALFKVDCLHIKVKDEYKVDCSNVNL
WMIDRQTWQKGLKEEAMALGVDVKENCPVNPTDLVSISQNYDWVIDCTGIPSTTSISKGFSHVYKNYWAYAHQITLFGNF
QNQLGELKVGVSPDYLGYYWIFPKSKDFANVGLGIFPQNNKYPETLKKRLKRELHNIIHREGLQNCKKVRKTGGVIPTKP
LDELVFDNIILAGDSGGFSSPLHGGGIDLALFTGKEAINAINEGEIDNYRQRLLDKAGAKLEIEQKIFDLWEQIGYENLD
RLLRLILKREAVFELPRLFQFRDLLISERQTITAFYDGFFQGNWDRISY
>Mature_368_residues
AVLGGGPAGLAASIQGAQQGLSVTLFEKNKVGENIKCAEGFYDSMKLFGPPSHGALFKVDCLHIKVKDEYKVDCSNVNLW
MIDRQTWQKGLKEEAMALGVDVKENCPVNPTDLVSISQNYDWVIDCTGIPSTTSISKGFSHVYKNYWAYAHQITLFGNFQ
NQLGELKVGVSPDYLGYYWIFPKSKDFANVGLGIFPQNNKYPETLKKRLKRELHNIIHREGLQNCKKVRKTGGVIPTKPL
DELVFDNIILAGDSGGFSSPLHGGGIDLALFTGKEAINAINEGEIDNYRQRLLDKAGAKLEIEQKIFDLWEQIGYENLDR
LLRLILKREAVFELPRLFQFRDLLISERQTITAFYDGFFQGNWDRISY

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR011777
- InterPro:   IPR003042
- InterPro:   IPR006905 [H]

Pfam domain/function: PF01266 DAO; PF04820 Trp_halogenase [H]

EC number: NA

Molecular weight: Translated: 41615; Mature: 41484

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLGGGPAGLAASIQGAQQGLSVTLFEKNKVGENIKCAEGFYDSMKLFGPPSHGALFKV
CCEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEE
DCLHIKVKDEYKVDCSNVNLWMIDRQTWQKGLKEEAMALGVDVKENCPVNPTDLVSISQN
EEEEEEECCCEEEEECCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCC
YDWVIDCTGIPSTTSISKGFSHVYKNYWAYAHQITLFGNFQNQLGELKVGVSPDYLGYYW
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHCCCCEEECCCCCCCEEEE
IFPKSKDFANVGLGIFPQNNKYPETLKKRLKRELHNIIHREGLQNCKKVRKTGGVIPTKP
EECCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDELVFDNIILAGDSGGFSSPLHGGGIDLALFTGKEAINAINEGEIDNYRQRLLDKAGAK
HHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHCCCC
LEIEQKIFDLWEQIGYENLDRLLRLILKREAVFELPRLFQFRDLLISERQTITAFYDGFF
EEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHHH
QGNWDRISY
CCCCCCCCC
>Mature Secondary Structure 
AVLGGGPAGLAASIQGAQQGLSVTLFEKNKVGENIKCAEGFYDSMKLFGPPSHGALFKV
CEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEE
DCLHIKVKDEYKVDCSNVNLWMIDRQTWQKGLKEEAMALGVDVKENCPVNPTDLVSISQN
EEEEEEECCCEEEEECCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCC
YDWVIDCTGIPSTTSISKGFSHVYKNYWAYAHQITLFGNFQNQLGELKVGVSPDYLGYYW
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHCCCCEEECCCCCCCEEEE
IFPKSKDFANVGLGIFPQNNKYPETLKKRLKRELHNIIHREGLQNCKKVRKTGGVIPTKP
EECCCCCHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LDELVFDNIILAGDSGGFSSPLHGGGIDLALFTGKEAINAINEGEIDNYRQRLLDKAGAK
HHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEECHHHHHHCCCCCHHHHHHHHHHHCCCC
LEIEQKIFDLWEQIGYENLDRLLRLILKREAVFELPRLFQFRDLLISERQTITAFYDGFF
EEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHHH
QGNWDRISY
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]