Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 188586318

GI number: 188586318

Start: 1776147

End: 1777115

Strand: Reverse

Name: gcp [H]

Synonym: Nther_1701

Alternate gene names: 188586318

Gene position: 1777115-1776147 (Counterclockwise)

Preceding gene: 188586319

Following gene: 188586317

Centisome position: 56.14

GC content: 35.6

Gene sequence:

>969_bases
ATGGGTTTAGATACGAGTTGTTATACTACATCTATGGCGGTAATTAACAAGCAAGGAAAGATTATTGCAAAAACTGAACG
CCCTTTAGAAGTTGCTATGGGAAAAGGCGGTTTAAGACAATCGGAAGCTGTTTTTCAACATATTAATAATCTTCCCCAAG
GACTAACTGAAATAAAAAAACAATTGAATGTCAATAATCTGGATTTAAACTTGGCTGCTATTGCAGTTAGCAGTAGACCA
CGTCCCATAGAAGGTTCATATATGCCCGTCTTTAAAGTGGGTGATTCTTATGCAAAGGCATTATCTTTGAGTAGTGGTAT
TCCTTTATTGGAATATACACATCAAGAGGGGCATATCGCTTCGATTGTATATGAAAAAAGCAACAATATTCGCCTTGAAG
ATATGGACAAGTTTCTGGTATTTCATGTTTCAGGAGGAACCACTGAATTATTAATCTGCCATACCAAGGGTAAATTTTCT
TCATTTGACATAGAAATAATTGGGGGAACAAAAGATATTGCAGCAGGACAATTAATAGATAGAACGGCAAAATTAATGAA
TCTGCCATTCCCTGGAGGTCCGCATTTAGAAAAACTTGGGGACCAATCAGGACAAACTGATATATCTGTTCCCTTTTCAG
TTGAAGATACTAAAATTAACTTTTCAGGCCCGGAAACTCATATTAAGAGATTGATACACAATGAGGATTACCCAAAGCCA
GCTGTTGCTAGGGGGATAGAGCAATGTGTTGCTAAATCGCTGTTAACAGTACTTGAAAATGCGCTCAAGAAACATCAAGT
AAAAAATATTTTATTTGTAGGTGGGGTCATGAGTAATTCGTATATTAAGAACTATTTATCAAAAAATATTTCCAATGAAA
AATACAATTTAATTTTTGGTAGCCCCGAACTATCCAAAGATAATGCTGTTGGGGTTGCCTGGCTCGGTTACAATAATTTT
TTTAATTAA

Upstream 100 bases:

>100_bases
AAAATTCAGTACAGATAAAGCCTCCGGGTATATTAATGGAATTCTTGACCAAGTTGCTAATCAATTGAATAAGGCGCGGT
GATAGCCGATGGAACTGCTA

Downstream 100 bases:

>100_bases
ACTCTGTTAATTGATTCATACAGCTTACGCACAAATTAACAGAGTTTTTAATTAAATAAGGTTAAATGAAGGGGAAGATA
TTAAGAGTTACTTAAAAGGA

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MGLDTSCYTTSMAVINKQGKIIAKTERPLEVAMGKGGLRQSEAVFQHINNLPQGLTEIKKQLNVNNLDLNLAAIAVSSRP
RPIEGSYMPVFKVGDSYAKALSLSSGIPLLEYTHQEGHIASIVYEKSNNIRLEDMDKFLVFHVSGGTTELLICHTKGKFS
SFDIEIIGGTKDIAAGQLIDRTAKLMNLPFPGGPHLEKLGDQSGQTDISVPFSVEDTKINFSGPETHIKRLIHNEDYPKP
AVARGIEQCVAKSLLTVLENALKKHQVKNILFVGGVMSNSYIKNYLSKNISNEKYNLIFGSPELSKDNAVGVAWLGYNNF
FN

Sequences:

>Translated_322_residues
MGLDTSCYTTSMAVINKQGKIIAKTERPLEVAMGKGGLRQSEAVFQHINNLPQGLTEIKKQLNVNNLDLNLAAIAVSSRP
RPIEGSYMPVFKVGDSYAKALSLSSGIPLLEYTHQEGHIASIVYEKSNNIRLEDMDKFLVFHVSGGTTELLICHTKGKFS
SFDIEIIGGTKDIAAGQLIDRTAKLMNLPFPGGPHLEKLGDQSGQTDISVPFSVEDTKINFSGPETHIKRLIHNEDYPKP
AVARGIEQCVAKSLLTVLENALKKHQVKNILFVGGVMSNSYIKNYLSKNISNEKYNLIFGSPELSKDNAVGVAWLGYNNF
FN
>Mature_321_residues
GLDTSCYTTSMAVINKQGKIIAKTERPLEVAMGKGGLRQSEAVFQHINNLPQGLTEIKKQLNVNNLDLNLAAIAVSSRPR
PIEGSYMPVFKVGDSYAKALSLSSGIPLLEYTHQEGHIASIVYEKSNNIRLEDMDKFLVFHVSGGTTELLICHTKGKFSS
FDIEIIGGTKDIAAGQLIDRTAKLMNLPFPGGPHLEKLGDQSGQTDISVPFSVEDTKINFSGPETHIKRLIHNEDYPKPA
VARGIEQCVAKSLLTVLENALKKHQVKNILFVGGVMSNSYIKNYLSKNISNEKYNLIFGSPELSKDNAVGVAWLGYNNFF
N

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=351, Percent_Identity=24.5014245014245, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789445, Length=327, Percent_Identity=24.7706422018349, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71995670, Length=286, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357207, Length=349, Percent_Identity=24.9283667621776, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35354; Mature: 35223

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLDTSCYTTSMAVINKQGKIIAKTERPLEVAMGKGGLRQSEAVFQHINNLPQGLTEIKK
CCCCCCHHHHEEEEEECCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
QLNVNNLDLNLAAIAVSSRPRPIEGSYMPVFKVGDSYAKALSLSSGIPLLEYTHQEGHIA
HCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEECCCCCEE
SIVYEKSNNIRLEDMDKFLVFHVSGGTTELLICHTKGKFSSFDIEIIGGTKDIAAGQLID
EEEEECCCCEEEEECCEEEEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHH
RTAKLMNLPFPGGPHLEKLGDQSGQTDISVPFSVEDTKINFSGPETHIKRLIHNEDYPKP
HHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCEEECCCHHHHHHHHHCCCCCCCH
AVARGIEQCVAKSLLTVLENALKKHQVKNILFVGGVMSNSYIKNYLSKNISNEKYNLIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEC
SPELSKDNAVGVAWLGYNNFFN
CCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
GLDTSCYTTSMAVINKQGKIIAKTERPLEVAMGKGGLRQSEAVFQHINNLPQGLTEIKK
CCCCCHHHHEEEEEECCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
QLNVNNLDLNLAAIAVSSRPRPIEGSYMPVFKVGDSYAKALSLSSGIPLLEYTHQEGHIA
HCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEECCCCCEE
SIVYEKSNNIRLEDMDKFLVFHVSGGTTELLICHTKGKFSSFDIEIIGGTKDIAAGQLID
EEEEECCCCEEEEECCEEEEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHH
RTAKLMNLPFPGGPHLEKLGDQSGQTDISVPFSVEDTKINFSGPETHIKRLIHNEDYPKP
HHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCEEECCCHHHHHHHHHCCCCCCCH
AVARGIEQCVAKSLLTVLENALKKHQVKNILFVGGVMSNSYIKNYLSKNISNEKYNLIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEC
SPELSKDNAVGVAWLGYNNFFN
CCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA