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The map label for this gene is surE

Identifier: 188586215

GI number: 188586215

Start: 1674525

End: 1675304

Strand: Reverse

Name: surE

Synonym: Nther_1598

Alternate gene names: 188586215

Gene position: 1675304-1674525 (Counterclockwise)

Preceding gene: 188586216

Following gene: 188586214

Centisome position: 52.92

GC content: 35.64

Gene sequence:

>780_bases
ATGAAAGTTTTACTTACTAATGACGATGGAATTTATGCACCTGGTATATTTGCAATGGCTAAAGAAATAGCTTCAAGGGA
TGAGTTTGAGGCTGTTGTAGTAGCTCCTGACCGAGAGCAAAGTGCTACTGGTCATGCTATTACTGTTCATAAACCATTAA
GGGTGAATAATGTTAAAAAACTTGGAGAGAAACTGGAAATACCATTTTATTCGGTTAATGGAACGCCGTCCGACTGTGTC
AAACTTGCTGTAGAATCTGTCATGGATGAAAAACCTGATTTGGTTATTTCTGGCATTAATCGAGGGGCAAATCTGGGGAC
TGATGTGCTTTATTCTGGTACTGTATCTGGCGCCATGGAAGCTGCTATTTTGAATATTAAATCCATCGCTGTTTCACTAG
TAGATTACGATTACGAGGATTATTCTACTGCTGCATCTTATACAGCATACATTGCCAATATTATAAAGGATAATCCTGAG
GAGTTTGAAAATGGTACTTTATTAAATGTTAATGTACCAGCAGTAGAAGCAAATCAATTAAAAGGAGTAAAAATTACCAG
GCAAGGATTTAGACAGTATGAAAATATTTTTGAAAAAAGATTTGACCCCCGAGGAAAAGCTTACTACTGGATGGCAGGAA
AAGTAATTGAAGATACATCAGATATTAAGACAGATGTTGCATCTGTAAAAGAAAATTATGTATCTGTAACACCAATTAAA
TATGATCTGACCGATTACAATCTATATAATAGCCTGTCTAATTGGGAATTTGATGACTAA

Upstream 100 bases:

>100_bases
ATGAAGAAAAAGTTTATCATGAAGCTGATAAACATGCAAAAATGATTACTGATCAAGATAAGAATTAAATTGATTCAGAC
TTGGAACTGGAGGGAAGACT

Downstream 100 bases:

>100_bases
TAATAAGGAGGCAAGTTTTGATGACTATTAATAATATTAATTCTTTTATTGATCATACTCAATTAAAGCCCGAAGCAACA
CCAGGTCAAATTGAAAAATT

Product: stationary-phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKKLGEKLEIPFYSVNGTPSDCV
KLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAMEAAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPE
EFENGTLLNVNVPAVEANQLKGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIK
YDLTDYNLYNSLSNWEFDD

Sequences:

>Translated_259_residues
MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKKLGEKLEIPFYSVNGTPSDCV
KLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAMEAAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPE
EFENGTLLNVNVPAVEANQLKGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIK
YDLTDYNLYNSLSNWEFDD
>Mature_259_residues
MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKKLGEKLEIPFYSVNGTPSDCV
KLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAMEAAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPE
EFENGTLLNVNVPAVEANQLKGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIK
YDLTDYNLYNSLSNWEFDD

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=255, Percent_Identity=39.2156862745098, Blast_Score=187, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_NATTJ (B2A4J5)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917760.1
- ProteinModelPortal:   B2A4J5
- GeneID:   6315777
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1598
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28724; Mature: 28724

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKK
CEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHH
LGEKLEIPFYSVNGTPSDCVKLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAME
HHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHH
AAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPEEFENGTLLNVNVPAVEANQL
HHHHHHHHHEEEEHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCC
KGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIK
CCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEECCCHHHHHHHHHHHHCCEEECEEE
YDLTDYNLYNSLSNWEFDD
EECCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKK
CEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEECCCCHHHHHH
LGEKLEIPFYSVNGTPSDCVKLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAME
HHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHH
AAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPEEFENGTLLNVNVPAVEANQL
HHHHHHHHHEEEEHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCC
KGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIK
CCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEECCCHHHHHHHHHHHHCCEEECEEE
YDLTDYNLYNSLSNWEFDD
EECCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA