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The map label for this gene is deoC

Identifier: 188586214

GI number: 188586214

Start: 1673842

End: 1674504

Strand: Reverse

Name: deoC

Synonym: Nther_1597

Alternate gene names: 188586214

Gene position: 1674504-1673842 (Counterclockwise)

Preceding gene: 188586215

Following gene: 188586213

Centisome position: 52.9

GC content: 37.1

Gene sequence:

>663_bases
ATGACTATTAATAATATTAATTCTTTTATTGATCATACTCAATTAAAGCCCGAAGCAACACCAGGTCAAATTGAAAAATT
ATGTCAAGAAGCTATTGATTATAAGTTTAAAGCTGTATGTGTAAACCCTGTTCATGTTAATTTAGCTGCCAATCTTTTAA
AGGACTCAGAAGTCGAAATTGCTTCTGTAGTAGGGTTTCCCCTGGGGGCTAGTGCTACCGATGTCAAAGAATATGAGGCC
AAAAAAGCTGTAGAACATGGTGCTAGTGAAATTGATATGGTAATCAATATAGGATTATTAAAAAATGAACAGGACATGGA
AGTGATTGAAGATATATCCAGCGTTGTTAACACCGTTCCAGTTGGCATTGTAGTAAAGGTTATTATCGAAACCTGTTTAT
TATCAGATGAAGAAAAAATCAAAGCCTGTGAACTGGCTAAAAGAGCTGGTGCCCATTATGTGAAAACCTCCACTGGTTTC
AGTAGCAGTGGAGCTACAGTAGAGGATGTCAAGATAATGAAAAAAACAGTTGGTGAAAAACTCGGTGTGAAAGCTTCAGG
CGGAATAAGGGACTTAGAAACCGCTCAAAAGATGATTGAAGCTGGGGCTACTAGAATTGGGGCAAGCAAGAGTGTTGAAA
TAGTTAAAAGCCAGAGTAATTAA

Upstream 100 bases:

>100_bases
TATCTGTAACACCAATTAAATATGATCTGACCGATTACAATCTATATAATAGCCTGTCTAATTGGGAATTTGATGACTAA
TAATAAGGAGGCAAGTTTTG

Downstream 100 bases:

>100_bases
GCTCTAACAAAATAAAAATTATAGATGATCATAAACAAGCCTTCACAATAAAGAAGGCTTGTTTTTTTATGACAAAAAAT
CAGATAAATATCAAAATTAT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTINNINSFIDHTQLKPEATPGQIEKLCQEAIDYKFKAVCVNPVHVNLAANLLKDSEVEIASVVGFPLGASATDVKEYEA
KKAVEHGASEIDMVINIGLLKNEQDMEVIEDISSVVNTVPVGIVVKVIIETCLLSDEEKIKACELAKRAGAHYVKTSTGF
SSSGATVEDVKIMKKTVGEKLGVKASGGIRDLETAQKMIEAGATRIGASKSVEIVKSQSN

Sequences:

>Translated_220_residues
MTINNINSFIDHTQLKPEATPGQIEKLCQEAIDYKFKAVCVNPVHVNLAANLLKDSEVEIASVVGFPLGASATDVKEYEA
KKAVEHGASEIDMVINIGLLKNEQDMEVIEDISSVVNTVPVGIVVKVIIETCLLSDEEKIKACELAKRAGAHYVKTSTGF
SSSGATVEDVKIMKKTVGEKLGVKASGGIRDLETAQKMIEAGATRIGASKSVEIVKSQSN
>Mature_219_residues
TINNINSFIDHTQLKPEATPGQIEKLCQEAIDYKFKAVCVNPVHVNLAANLLKDSEVEIASVVGFPLGASATDVKEYEAK
KAVEHGASEIDMVINIGLLKNEQDMEVIEDISSVVNTVPVGIVVKVIIETCLLSDEEKIKACELAKRAGAHYVKTSTGFS
SSGATVEDVKIMKKTVGEKLGVKASGGIRDLETAQKMIEAGATRIGASKSVEIVKSQSN

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=251, Percent_Identity=29.4820717131474, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1790841, Length=214, Percent_Identity=32.2429906542056, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_NATTJ (B2A4J4)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917759.1
- ProteinModelPortal:   B2A4J4
- SMR:   B2A4J4
- GeneID:   6315776
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1597
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23514; Mature: 23383

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINNINSFIDHTQLKPEATPGQIEKLCQEAIDYKFKAVCVNPVHVNLAANLLKDSEVEI
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEECCEEEHHHHHHHCCCCHHH
ASVVGFPLGASATDVKEYEAKKAVEHGASEIDMVINIGLLKNEQDMEVIEDISSVVNTVP
HHHHCCCCCCCCHHHHHHHHHHHHHCCCHHEEHEEEEEECCCCHHHHHHHHHHHHHHHHH
VGIVVKVIIETCLLSDEEKIKACELAKRAGAHYVKTSTGFSSSGATVEDVKIMKKTVGEK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGVKASGGIRDLETAQKMIEAGATRIGASKSVEIVKSQSN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
>Mature Secondary Structure 
TINNINSFIDHTQLKPEATPGQIEKLCQEAIDYKFKAVCVNPVHVNLAANLLKDSEVEI
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEECCEEEHHHHHHHCCCCHHH
ASVVGFPLGASATDVKEYEAKKAVEHGASEIDMVINIGLLKNEQDMEVIEDISSVVNTVP
HHHHCCCCCCCCHHHHHHHHHHHHHCCCHHEEHEEEEEECCCCHHHHHHHHHHHHHHHHH
VGIVVKVIIETCLLSDEEKIKACELAKRAGAHYVKTSTGFSSSGATVEDVKIMKKTVGEK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGVKASGGIRDLETAQKMIEAGATRIGASKSVEIVKSQSN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA