BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is yhdH [H]

Identifier: 188584672

GI number: 188584672

Start: 43979

End: 45328

Strand: Direct

Name: yhdH [H]

Synonym: Nther_0030

Alternate gene names: 188584672

Gene position: 43979-45328 (Clockwise)

Preceding gene: 188584671

Following gene: 188584673

Centisome position: 1.39

GC content: 40.07

Gene sequence:

>1350_bases
ATGCCAAATGAACCAAGAGAACAATGGGCATCTAGATTAGGTTTTGTCCTAGCAGCAGCAGGATCAGCAGTTGGATTAGG
TAATATTTGGAGATTCCCCTATGTTGTTGGTGAACACGGTGGTGCTGCTTTTTTATTTCTCTATCTTATTGCAATAGTAT
TAATCGGTTATCCTGTAATGATTACTGAAATTTCTATGGGAAGAAGTACTCAGAAGAACCCTGTAGGTGCTTTTAAAGCC
CTAGCTCCTAATACACCCTGGTGGCTCGTAGGGGGATTGGGTGTTCTTACTGGATTTGTAATTTTGAGTTTTTATTCCGT
TATTGCCGGTTGGTCTATGTCTTATATTTTTAAAGCTATTGCTGGTTTTCCGGAAGGAGCTGGTGCCAATGAACAATTAT
TTGGTCAGCATATCGCCGGGGTAGCCGAGCCATTAATATATCATTTTATTTTTATGGTAATAACTGTTGGAGTGATTGCA
GCAGGTGTAGTTAAAGGAATTCAGCGAATTGTGGAATTATTAATGCCGATTTTGGTCGTCTTACTATTAATAGTTGTGTT
TAGAGGTGTTACTTTAGAGGGTGCGGGAGAAGGTTTAGCATTCTTATTTAGCCCTGATTTTAGTGCTGTGCAGCCTGAAA
CAATCCTAAGTGCTATTGGTCAATCCTTTTTTACTTTGAGTTTGGGTATGGGAGCTATTATCACTTACGGTAGTTATCTT
TCTAGTAAGGATGAAGTGCCTAATAGTGCAATTCAAATTATCGGTGCAGATACAGGGATTGCAATTTTGGCAGGTTTGGC
CATCTTTCCAGCGATGTTCGCCCTGGGTTTTGAAACAACTCAAGGCCCTGGATTGGTATTTATTACTTTACCTGCAGTAT
TTGCTGAAATGCCAATGGGAGAGCTATTCGGATTCTTATTCTTCCTGTTATTGTCAATTGCGGCTTTAACTTCTGCAATT
TCACTTCTCGAGGTTGTGGCGGCATATGTTATAGATGAGAAAAACTGGCCTAGGAAAAAGGCAGCTGCTGTGGTAGGAGC
TATCATTTTTGTAGTTGGTATCCCACCGGCACTCCATGCTGGGGTCTTATCAGATGTGACAATCATTGGAATGGATATGC
TTGATTTTTACGATTTTATTTCTGATAGTATTATGTTGCCCCTAGGTGGTGTCTTGACTGTAATTTTTGCTGGCCACGTT
TGGGGGATGAAAAATGTTGCTGATGAAGCCAACAAGGGTTCTCGAGGATTAAAAATAGGTCACTGGATGGAACCATTGCT
TAAATATGTAATTCCCCTCGGTGTTTTAATAGTAATGATTGTGGGAATTATTGATACTTTAGGTGGATAA

Upstream 100 bases:

>100_bases
AGGACAATTCCAAAAATTTCAAACATTTATAGGGGGGTGGTAAATATAAGGTGATGGATTTTGGACTTAATTTAGTAAAC
AGATAACAAGGAGGGTTAAT

Downstream 100 bases:

>100_bases
GGCATCACTAATACGAATGTCAACTTTACAATAACCCTGGTCTTTCGGACCAGGGTTATTTTGTGCATGAGCCATTAAAG
GATTATTTACCTTTCGTACA

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPNEPREQWASRLGFVLAAAGSAVGLGNIWRFPYVVGEHGGAAFLFLYLIAIVLIGYPVMITEISMGRSTQKNPVGAFKA
LAPNTPWWLVGGLGVLTGFVILSFYSVIAGWSMSYIFKAIAGFPEGAGANEQLFGQHIAGVAEPLIYHFIFMVITVGVIA
AGVVKGIQRIVELLMPILVVLLLIVVFRGVTLEGAGEGLAFLFSPDFSAVQPETILSAIGQSFFTLSLGMGAIITYGSYL
SSKDEVPNSAIQIIGADTGIAILAGLAIFPAMFALGFETTQGPGLVFITLPAVFAEMPMGELFGFLFFLLLSIAALTSAI
SLLEVVAAYVIDEKNWPRKKAAAVVGAIIFVVGIPPALHAGVLSDVTIIGMDMLDFYDFISDSIMLPLGGVLTVIFAGHV
WGMKNVADEANKGSRGLKIGHWMEPLLKYVIPLGVLIVMIVGIIDTLGG

Sequences:

>Translated_449_residues
MPNEPREQWASRLGFVLAAAGSAVGLGNIWRFPYVVGEHGGAAFLFLYLIAIVLIGYPVMITEISMGRSTQKNPVGAFKA
LAPNTPWWLVGGLGVLTGFVILSFYSVIAGWSMSYIFKAIAGFPEGAGANEQLFGQHIAGVAEPLIYHFIFMVITVGVIA
AGVVKGIQRIVELLMPILVVLLLIVVFRGVTLEGAGEGLAFLFSPDFSAVQPETILSAIGQSFFTLSLGMGAIITYGSYL
SSKDEVPNSAIQIIGADTGIAILAGLAIFPAMFALGFETTQGPGLVFITLPAVFAEMPMGELFGFLFFLLLSIAALTSAI
SLLEVVAAYVIDEKNWPRKKAAAVVGAIIFVVGIPPALHAGVLSDVTIIGMDMLDFYDFISDSIMLPLGGVLTVIFAGHV
WGMKNVADEANKGSRGLKIGHWMEPLLKYVIPLGVLIVMIVGIIDTLGG
>Mature_448_residues
PNEPREQWASRLGFVLAAAGSAVGLGNIWRFPYVVGEHGGAAFLFLYLIAIVLIGYPVMITEISMGRSTQKNPVGAFKAL
APNTPWWLVGGLGVLTGFVILSFYSVIAGWSMSYIFKAIAGFPEGAGANEQLFGQHIAGVAEPLIYHFIFMVITVGVIAA
GVVKGIQRIVELLMPILVVLLLIVVFRGVTLEGAGEGLAFLFSPDFSAVQPETILSAIGQSFFTLSLGMGAIITYGSYLS
SKDEVPNSAIQIIGADTGIAILAGLAIFPAMFALGFETTQGPGLVFITLPAVFAEMPMGELFGFLFFLLLSIAALTSAIS
LLEVVAAYVIDEKNWPRKKAAAVVGAIIFVVGIPPALHAGVLSDVTIIGMDMLDFYDFISDSIMLPLGGVLTVIFAGHVW
GMKNVADEANKGSRGLKIGHWMEPLLKYVIPLGVLIVMIVGIIDTLGG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=431, Percent_Identity=27.3781902552204, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI21361581, Length=488, Percent_Identity=24.5901639344262, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI194018524, Length=312, Percent_Identity=31.0897435897436, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI171184408, Length=488, Percent_Identity=25.6147540983607, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI171184406, Length=488, Percent_Identity=25.6147540983607, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI171184404, Length=488, Percent_Identity=25.6147540983607, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI7657587, Length=382, Percent_Identity=25.130890052356, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI4507043, Length=404, Percent_Identity=24.009900990099, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI51468073, Length=319, Percent_Identity=26.6457680250784, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI197276623, Length=481, Percent_Identity=25.987525987526, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI54607094, Length=481, Percent_Identity=25.987525987526, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI58219014, Length=313, Percent_Identity=27.4760383386581, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI134304856, Length=503, Percent_Identity=25.6461232604374, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4507041, Length=386, Percent_Identity=25.1295336787565, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI289191351, Length=499, Percent_Identity=22.2444889779559, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557046, Length=499, Percent_Identity=22.2444889779559, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI289191377, Length=499, Percent_Identity=22.2444889779559, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI11181770, Length=313, Percent_Identity=27.7955271565495, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI33354281, Length=313, Percent_Identity=27.4760383386581, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI5032097, Length=512, Percent_Identity=24.0234375, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI67782317, Length=440, Percent_Identity=23.4090909090909, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI218563756, Length=512, Percent_Identity=23.828125, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI67782313, Length=440, Percent_Identity=23.4090909090909, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI12408638, Length=283, Percent_Identity=27.9151943462898, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI67782315, Length=440, Percent_Identity=23.4090909090909, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI21361693, Length=121, Percent_Identity=38.0165289256198, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI92859670, Length=132, Percent_Identity=35.6060606060606, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI197276625, Length=137, Percent_Identity=35.7664233576642, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI300360519, Length=297, Percent_Identity=25.2525252525253, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI6005715, Length=174, Percent_Identity=30.4597701149425, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI55749589, Length=279, Percent_Identity=24.0143369175627, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI289191353, Length=306, Percent_Identity=21.8954248366013, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=435, Percent_Identity=27.1264367816092, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25146584, Length=423, Percent_Identity=26.4775413711584, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17554804, Length=481, Percent_Identity=25.5717255717256, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71998244, Length=420, Percent_Identity=28.8095238095238, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71995588, Length=415, Percent_Identity=24.8192771084337, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17569475, Length=422, Percent_Identity=23.4597156398104, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133952791, Length=255, Percent_Identity=27.4509803921569, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI212642127, Length=245, Percent_Identity=27.7551020408163, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115534083, Length=134, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=119, Percent_Identity=36.1344537815126, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542050, Length=117, Percent_Identity=34.1880341880342, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17136952, Length=380, Percent_Identity=27.8947368421053, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281364394, Length=380, Percent_Identity=27.8947368421053, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574704, Length=380, Percent_Identity=27.8947368421053, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17136950, Length=380, Percent_Identity=27.8947368421053, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574702, Length=380, Percent_Identity=27.8947368421053, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24639514, Length=511, Percent_Identity=23.8747553816047, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI221329674, Length=510, Percent_Identity=23.921568627451, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24639516, Length=528, Percent_Identity=23.1060606060606, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281363702, Length=493, Percent_Identity=26.5720081135903, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24582567, Length=454, Percent_Identity=25.7709251101322, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24661428, Length=501, Percent_Identity=23.75249500998, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24652942, Length=464, Percent_Identity=25, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45551088, Length=464, Percent_Identity=25, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45550877, Length=434, Percent_Identity=25.3456221198157, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19921936, Length=506, Percent_Identity=22.7272727272727, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45551183, Length=426, Percent_Identity=25.1173708920188, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24762620, Length=421, Percent_Identity=26.603325415677, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24655079, Length=532, Percent_Identity=23.6842105263158, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281364136, Length=403, Percent_Identity=26.0545905707196, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24654186, Length=532, Percent_Identity=24.4360902255639, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281363700, Length=340, Percent_Identity=30, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365034, Length=508, Percent_Identity=23.8188976377953, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24639853, Length=485, Percent_Identity=25.360824742268, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24582569, Length=415, Percent_Identity=23.3734939759036, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19921352, Length=308, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24584353, Length=308, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47574; Mature: 47443

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNEPREQWASRLGFVLAAAGSAVGLGNIWRFPYVVGEHGGAAFLFLYLIAIVLIGYPVM
CCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHH
ITEISMGRSTQKNPVGAFKALAPNTPWWLVGGLGVLTGFVILSFYSVIAGWSMSYIFKAI
EEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGFPEGAGANEQLFGQHIAGVAEPLIYHFIFMVITVGVIAAGVVKGIQRIVELLMPILVV
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIVVFRGVTLEGAGEGLAFLFSPDFSAVQPETILSAIGQSFFTLSLGMGAIITYGSYL
HHHHHHHCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSKDEVPNSAIQIIGADTGIAILAGLAIFPAMFALGFETTQGPGLVFITLPAVFAEMPMG
CCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCHH
ELFGFLFFLLLSIAALTSAISLLEVVAAYVIDEKNWPRKKAAAVVGAIIFVVGIPPALHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
GVLSDVTIIGMDMLDFYDFISDSIMLPLGGVLTVIFAGHVWGMKNVADEANKGSRGLKIG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHH
HWMEPLLKYVIPLGVLIVMIVGIIDTLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNEPREQWASRLGFVLAAAGSAVGLGNIWRFPYVVGEHGGAAFLFLYLIAIVLIGYPVM
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHH
ITEISMGRSTQKNPVGAFKALAPNTPWWLVGGLGVLTGFVILSFYSVIAGWSMSYIFKAI
EEEECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGFPEGAGANEQLFGQHIAGVAEPLIYHFIFMVITVGVIAAGVVKGIQRIVELLMPILVV
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIVVFRGVTLEGAGEGLAFLFSPDFSAVQPETILSAIGQSFFTLSLGMGAIITYGSYL
HHHHHHHCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSKDEVPNSAIQIIGADTGIAILAGLAIFPAMFALGFETTQGPGLVFITLPAVFAEMPMG
CCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCHH
ELFGFLFFLLLSIAALTSAISLLEVVAAYVIDEKNWPRKKAAAVVGAIIFVVGIPPALHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
GVLSDVTIIGMDMLDFYDFISDSIMLPLGGVLTVIFAGHVWGMKNVADEANKGSRGLKIG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCHH
HWMEPLLKYVIPLGVLIVMIVGIIDTLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]