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The map label for this gene is speA [H]

Identifier: 188584673

GI number: 188584673

Start: 45502

End: 46953

Strand: Direct

Name: speA [H]

Synonym: Nther_0031

Alternate gene names: 188584673

Gene position: 45502-46953 (Clockwise)

Preceding gene: 188584672

Following gene: 188584674

Centisome position: 1.44

GC content: 35.67

Gene sequence:

>1452_bases
ATGGATTCCTTACAACAGGCCATAGATGAGTACATAAAAAATCAATACTCTAGATACCATACACCAGGACATATAGGTGG
TGAGGGCAGTCCTGCCATATCATTATTGGGGGAACAAGTATTTAAAGCTGATCTGACTGAATTACCTGGACTCGACGATC
TACATGCTCCAGAAAATGTGATTAAAAATGCTCAATCCAGGGCAGCCCAAGTCTTTGGAGCCGATTTTACTCATTTTTTA
GTTAATGGATCTTCAGCTGGAATTATTGCTATGATCCTTGCAATGGTTGAGCCAGGAAAAAAACTGGCAGTTCCCCGAAA
TGCTCATCGATCCGTCTATCATGGTTTGATTTTATCTGGTGCTATTCCCGAATATATACCTGTTGAGGTCCCCAAAGAAA
GTCCTGTAGCCTTCAATATATCTCCAGATGAATTGAATAACACTATCTCAACAAATATTGATAGTTCAAAAACACCTGAA
GCTGTTTTGATTACTAATCCTAGTTACCACGGAGTTGCCATTGATATGAACAAAGTTGCATTGGATAGTAATATACCCTT
GCTAGTTGACGAAGCCCATGGAGCACATTTTATTTTTTCAAAGGATTTGCCTCCTGATGCTTCAGAATATGGTGGCGATT
TGTGGGTTCAAAGTACACATAAAACTCTAGGTTCTCTTACTCAAAGTTCCATGCTTCATGGAATTGAAAATTTGGTTTCT
CGGGAAAAATTAGCTTTTATGCTACAACTTGTGCAAACCACTAGTCCATCATATCCTTTAATGGCATCATTAGAATCTGT
AATCGAATATGCTGACAAATATCATAAACATTGGCAGGAATTTATTAGCAACAGGTTAAAATATATTAGAAATAAAATTT
GCGAAATTCCAGGATTACAACTGGTGACACCAGAACAAATTACGACAGGATTTAAATTGGACCCGTCTAAGTTAACTATT
GATTTACGGGAACTAAATATTTCCGGGTATAAATTATCAGATTTACTCCGAAATGAATTTGGAATTCAGGTTGAATTGGT
AGATAGTAATAGTATTATGCTTATGTTAACTCCATATCACACGGAGAGGGAGTTAGATTATCTTATAAATAGCCTGGAAA
CAATAGTAAACAATAAAAATAGTTATCAAATTGTCAATAATACTGTAGATAAACAATTAGTAGCAAAAACAGATATTCCC
TATCCACAAGTTGAGATTACTCCTAGAGAAGCAGTTTACCAAGAAGGAGAGTATATTGAACTATCTGAAGCTATTGGAAG
AGTAGCCCAAGAATTTGTTATTCCTTATCCTCCGGGAATACCTGCATTAGTACCAGGAGAAATTATAACAGGGGATGTAT
ATGAATATTTAAATAAATTAACGGAAAATCCTGAAATACATATACAGGGATTTTACTACAGCAGTTCTAGCTACATTAAA
GTGATAAGATGA

Upstream 100 bases:

>100_bases
ATTAAAGGATTATTTACCTTTCGTACAGAATATTAATGTGATATAAATTATATAGTAAAAAATAACAATTATAATAAAAA
ACATGATGGAGGCCATAAAT

Downstream 100 bases:

>100_bases
ATCTATTAGAATCTATAACATACAAGGGTGATTACTGTGGAAGAATTTAACCAAGAGTTGAAATTAATGTTGGAGATATT
TCCTCCTCATATAAGGGAAA

Product: Orn/Lys/Arg decarboxylase major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MDSLQQAIDEYIKNQYSRYHTPGHIGGEGSPAISLLGEQVFKADLTELPGLDDLHAPENVIKNAQSRAAQVFGADFTHFL
VNGSSAGIIAMILAMVEPGKKLAVPRNAHRSVYHGLILSGAIPEYIPVEVPKESPVAFNISPDELNNTISTNIDSSKTPE
AVLITNPSYHGVAIDMNKVALDSNIPLLVDEAHGAHFIFSKDLPPDASEYGGDLWVQSTHKTLGSLTQSSMLHGIENLVS
REKLAFMLQLVQTTSPSYPLMASLESVIEYADKYHKHWQEFISNRLKYIRNKICEIPGLQLVTPEQITTGFKLDPSKLTI
DLRELNISGYKLSDLLRNEFGIQVELVDSNSIMLMLTPYHTERELDYLINSLETIVNNKNSYQIVNNTVDKQLVAKTDIP
YPQVEITPREAVYQEGEYIELSEAIGRVAQEFVIPYPPGIPALVPGEIITGDVYEYLNKLTENPEIHIQGFYYSSSSYIK
VIR

Sequences:

>Translated_483_residues
MDSLQQAIDEYIKNQYSRYHTPGHIGGEGSPAISLLGEQVFKADLTELPGLDDLHAPENVIKNAQSRAAQVFGADFTHFL
VNGSSAGIIAMILAMVEPGKKLAVPRNAHRSVYHGLILSGAIPEYIPVEVPKESPVAFNISPDELNNTISTNIDSSKTPE
AVLITNPSYHGVAIDMNKVALDSNIPLLVDEAHGAHFIFSKDLPPDASEYGGDLWVQSTHKTLGSLTQSSMLHGIENLVS
REKLAFMLQLVQTTSPSYPLMASLESVIEYADKYHKHWQEFISNRLKYIRNKICEIPGLQLVTPEQITTGFKLDPSKLTI
DLRELNISGYKLSDLLRNEFGIQVELVDSNSIMLMLTPYHTERELDYLINSLETIVNNKNSYQIVNNTVDKQLVAKTDIP
YPQVEITPREAVYQEGEYIELSEAIGRVAQEFVIPYPPGIPALVPGEIITGDVYEYLNKLTENPEIHIQGFYYSSSSYIK
VIR
>Mature_483_residues
MDSLQQAIDEYIKNQYSRYHTPGHIGGEGSPAISLLGEQVFKADLTELPGLDDLHAPENVIKNAQSRAAQVFGADFTHFL
VNGSSAGIIAMILAMVEPGKKLAVPRNAHRSVYHGLILSGAIPEYIPVEVPKESPVAFNISPDELNNTISTNIDSSKTPE
AVLITNPSYHGVAIDMNKVALDSNIPLLVDEAHGAHFIFSKDLPPDASEYGGDLWVQSTHKTLGSLTQSSMLHGIENLVS
REKLAFMLQLVQTTSPSYPLMASLESVIEYADKYHKHWQEFISNRLKYIRNKICEIPGLQLVTPEQITTGFKLDPSKLTI
DLRELNISGYKLSDLLRNEFGIQVELVDSNSIMLMLTPYHTERELDYLINSLETIVNNKNSYQIVNNTVDKQLVAKTDIP
YPQVEITPREAVYQEGEYIELSEAIGRVAQEFVIPYPPGIPALVPGEIITGDVYEYLNKLTENPEIHIQGFYYSSSSYIK
VIR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=589, Percent_Identity=25.2971137521222, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082193, Length=588, Percent_Identity=25.3401360544218, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786384, Length=560, Percent_Identity=25.1785714285714, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790573, Length=567, Percent_Identity=24.3386243386243, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI221142684, Length=297, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53769; Mature: 53769

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLQQAIDEYIKNQYSRYHTPGHIGGEGSPAISLLGEQVFKADLTELPGLDDLHAPENV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IKNAQSRAAQVFGADFTHFLVNGSSAGIIAMILAMVEPGKKLAVPRNAHRSVYHGLILSG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCC
AIPEYIPVEVPKESPVAFNISPDELNNTISTNIDSSKTPEAVLITNPSYHGVAIDMNKVA
CCCCCCCCCCCCCCCEEEECCHHHHCCCEECCCCCCCCCCEEEEECCCCCEEEEEECEEE
LDSNIPLLVDEAHGAHFIFSKDLPPDASEYGGDLWVQSTHKTLGSLTQSSMLHGIENLVS
ECCCCCEEEECCCCCEEEEECCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
REKLAFMLQLVQTTSPSYPLMASLESVIEYADKYHKHWQEFISNRLKYIRNKICEIPGLQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LVTPEQITTGFKLDPSKLTIDLRELNISGYKLSDLLRNEFGIQVELVDSNSIMLMLTPYH
EECHHHHCCCCEECCHHEEEEEEEECCCCEEHHHHHHHHCCCEEEEECCCCEEEEECCCC
TERELDYLINSLETIVNNKNSYQIVNNTVDKQLVAKTDIPYPQVEITPREAVYQEGEYIE
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCHHHHHCCCCEEE
LSEAIGRVAQEFVIPYPPGIPALVPGEIITGDVYEYLNKLTENPEIHIQGFYYSSSSYIK
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCCEEEEEEEECCCCEEE
VIR
EEC
>Mature Secondary Structure
MDSLQQAIDEYIKNQYSRYHTPGHIGGEGSPAISLLGEQVFKADLTELPGLDDLHAPENV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IKNAQSRAAQVFGADFTHFLVNGSSAGIIAMILAMVEPGKKLAVPRNAHRSVYHGLILSG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCC
AIPEYIPVEVPKESPVAFNISPDELNNTISTNIDSSKTPEAVLITNPSYHGVAIDMNKVA
CCCCCCCCCCCCCCCEEEECCHHHHCCCEECCCCCCCCCCEEEEECCCCCEEEEEECEEE
LDSNIPLLVDEAHGAHFIFSKDLPPDASEYGGDLWVQSTHKTLGSLTQSSMLHGIENLVS
ECCCCCEEEECCCCCEEEEECCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
REKLAFMLQLVQTTSPSYPLMASLESVIEYADKYHKHWQEFISNRLKYIRNKICEIPGLQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LVTPEQITTGFKLDPSKLTIDLRELNISGYKLSDLLRNEFGIQVELVDSNSIMLMLTPYH
EECHHHHCCCCEECCHHEEEEEEEECCCCEEHHHHHHHHCCCEEEEECCCCEEEEECCCC
TERELDYLINSLETIVNNKNSYQIVNNTVDKQLVAKTDIPYPQVEITPREAVYQEGEYIE
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCHHHHHCCCCEEE
LSEAIGRVAQEFVIPYPPGIPALVPGEIITGDVYEYLNKLTENPEIHIQGFYYSSSSYIK
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCCEEEEEEEECCCCEEE
VIR
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]