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The map label for this gene is flhF

Identifier: 188527221

GI number: 188527221

Start: 407435

End: 408814

Strand: Direct

Name: flhF

Synonym: HPSH_02140

Alternate gene names: 188527221

Gene position: 407435-408814 (Clockwise)

Preceding gene: 188527220

Following gene: 188527222

Centisome position: 25.33

GC content: 39.06

Gene sequence:

>1380_bases
GTGGTGAAATTCTATACCTATAGTGGGGAGACGGCCGCTGAAGCTTTAAAGATCGCTCAAAGCCACCATGGGGTGGATAC
GCTGGTGTTTAAAACCCAAGAAATCCGTAAAAAAACGCTCACTTCTTCTGGGCTTTATGAAATCGTTGTGGCGGTTGAAG
AAGAAAGCGAAAACAAACCCCCTAAAGCCCCCCTTATTCCAGAAAGTTTGTATGATGAAGAATTGAATGAAGAAGATGTG
GTCATGCAGCTTTCAAGCACTGTAGAAGAAATGCGCAAACTCGCCGGGGTTTCATCCAGTCAGCGCAATTATAGTTTTTC
AAAAAATAAGACCCTTTTAGAAAAAGACGCTCCATTAGAGGATACGCCTTTAGAGGCTAATCAACAAGACGCTTTATTGC
AAGCTTTAAAAGATGAAGCCAACCATAAAAAAGAAAGAGAAAAAAGAGAAGTCAAACAAGAAGAAGAAATTAAAGGCATC
AATCTGCAATTAAGCAAAATCAGAGACAGCCTGAAGCTCATTCAAAACATGTTTTGGGATGAGAAAAACCCTAATTCTAT
TAATATCCCTCAAGAATTTGCAGAAATTTACAAACTGGCCAAACAAAGCGGGATGAAATCCAGCCATTTAGATGAAATCA
TGCAATTGAGCTTGGAATTGATGCCTTTACGCATGCGGGAAAATTCCGTAACGATCAAGCGTTATTTTAGAGAAGTGTTG
CGCAAAATGATCCTATGCCGCCCTGAAGATTTGAATTTAAGGCAAAAACGCATTTTAATGCTCGTAGGGCCAACAGGCGT
GGGGAAAACGACGACTTTAGCTAAATTGGCCGCGCGCTATTCTAGGATGTTAGCTAAAAAATACAAGGTGGGCATTATCA
CTTTAGACAATTATCGCATTGGGGCTTTGGAGCAATTAAGCTGGTATGCTAATAAAATGAAAATGAGTATAGAAGCGGTG
ATTGACGCTAAAGATTTTGCTAAAGAAATTGAAGCGTTGGAATACTGCGATTTTATTTTAGTGGATACGACAGGGCATTC
GCAATACGATAAAGAAAAAATTGCCGGTTTGAAAGAATTTATAGATGGGGGTTATAATATTGATGTGTCCTTAGTGCTTT
CGGTTACCACTAAGTATGAAGACATGAAAGATATTTATGATTCTTTTGGGGTGTTAGGGATTGACACTTTAATCTTTACG
AAATTAGATGAGAGTAGGGGGTTAGGGAATTTGTTTTCTTTAGTGCATGAAAGCCAAAAGCCTATCAGCTATCTTTCTGT
TGGACAAGAAGTGCCTATGGATTTGAAAGTGGCCACTAATGAATATTTAGTGGATTGCATGCTAGATGGCTTTAGTAACC
CTAATAAGGAACAAGCATGA

Upstream 100 bases:

>100_bases
TAAGACAGAACGATTTGACTTTACCTCATCCTAAATGGAGTGAAAGGGATTCGGTGTTAGTGCCGTTGGCTTTGCAACAA
ATTCTTTTTAAAAAAGGGGA

Downstream 100 bases:

>100_bases
ACAATCAAGCGAGTCGCTTAGATAATTTGATCAATATTAAAAACCCCAAAAGTTTTTTTGACAATAAAGGGAATACCAAA
TTCATCGCTATCACAAGCGG

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPPKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRNYSFSKNKTLLEKDAPLEDTPLEANQQDALLQALKDEANHKKEREKREVKQEEEIKGI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA

Sequences:

>Translated_459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPPKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRNYSFSKNKTLLEKDAPLEDTPLEANQQDALLQALKDEANHKKEREKREVKQEEEIKGI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
>Mature_459_residues
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKPPKAPLIPESLYDEELNEEDV
VMQLSSTVEEMRKLAGVSSSQRNYSFSKNKTLLEKDAPLEDTPLEANQQDALLQALKDEANHKKEREKREVKQEEEIKGI
NLQLSKIRDSLKLIQNMFWDEKNPNSINIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
RKMILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRIGALEQLSWYANKMKMSIEAV
IDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEFIDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFT
KLDESRGLGNLFSLVHESQKPISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Escherichia coli, GI1789874, Length=217, Percent_Identity=27.1889400921659, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325345, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 52305; Mature: 52305

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKP
CEEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PKAPLIPESLYDEELNEEDVVMQLSSTVEEMRKLAGVSSSQRNYSFSKNKTLLEKDAPLE
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
DTPLEANQQDALLQALKDEANHKKEREKREVKQEEEIKGINLQLSKIRDSLKLIQNMFWD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCC
EKNPNSINIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
RKMILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRI
HHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
GALEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEF
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
IDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQK
HCCCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
PISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
CHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVKFYTYSGETAAEALKIAQSHHGVDTLVFKTQEIRKKTLTSSGLYEIVVAVEEESENKP
CEEEEEECCCHHHHHHHHHHHCCCCHHEEECHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PKAPLIPESLYDEELNEEDVVMQLSSTVEEMRKLAGVSSSQRNYSFSKNKTLLEKDAPLE
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
DTPLEANQQDALLQALKDEANHKKEREKREVKQEEEIKGINLQLSKIRDSLKLIQNMFWD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCC
EKNPNSINIPQEFAEIYKLAKQSGMKSSHLDEIMQLSLELMPLRMRENSVTIKRYFREVL
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
RKMILCRPEDLNLRQKRILMLVGPTGVGKTTTLAKLAARYSRMLAKKYKVGIITLDNYRI
HHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
GALEQLSWYANKMKMSIEAVIDAKDFAKEIEALEYCDFILVDTTGHSQYDKEKIAGLKEF
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
IDGGYNIDVSLVLSVTTKYEDMKDIYDSFGVLGIDTLIFTKLDESRGLGNLFSLVHESQK
HCCCCCEEEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
PISYLSVGQEVPMDLKVATNEYLVDCMLDGFSNPNKEQA
CHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]