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The map label for this gene is resD [H]

Identifier: 187933012

GI number: 187933012

Start: 1966462

End: 1967145

Strand: Reverse

Name: resD [H]

Synonym: CLL_A1866

Alternate gene names: 187933012

Gene position: 1967145-1966462 (Counterclockwise)

Preceding gene: 187933837

Following gene: 187935541

Centisome position: 51.76

GC content: 25.73

Gene sequence:

>684_bases
ATGATTAATATATTGCTTGTAGATGATGAAAAAAAGATATGTGAATTTGTAAAAGCATATTTAGATAAAGAAGGTTTTGT
AACGGATGAAGCTAATGATGGATGTACTGCAATAAGATACTTTGATTTAAATAGATATGATCTTGTGATTTTAGATAGAA
TGTTACCTGATATAAGTGGAGAAGAAGTGTGCAATCATATTAGAAATAAATCTGATGTACCTATAATAATGTTAACTGCA
AAAATAGATGAAGAAGATAGATTAGGTGGATTCAAACTAGGGTGTGACGATTACTTATGTAAGCCTTTTAATATTAAAGA
GCTTATATTTAGAGTAAAATCTATTTTAAAGAGAAGTGGCAAAATAGATTTTAGAGATATTATGAAATTTAAACAAGGAA
TAGAAATAAATACATCATCACATGAGGTTACTGTAAGAGGAAAAAAGATATTATTAACTAATACAGAATACAAGATATTA
TTATTGATGGCATCAAATCCTCAAAAAATATATAGTAGAGAAGAACTTTTAGAAAGTGTGATAGAAGAATATTATGAAAA
AATGGATAGAGTAATTGATAGTCATATAAAAAATTTAAGGCAAAAAATTGAAGTTAATTCAAGGGATTGCAAGATAATAA
AAACTATTTATGGGGTAGGATATAGATTTGAATTACAAGATTAA

Upstream 100 bases:

>100_bases
GTAGATACATGCGCTCTTATAATTTACTTTACCTTAGCCAAATTATTTTTAGGAATATAAAGTTCTATGTTTCTAAATAA
GTTTAGAGGAGAATTATACT

Downstream 100 bases:

>100_bases
AAGTATATCATTAAGAAATACAATTTTAATATCATTTACTATAATCATGACTTTAACCATTTTTACAATATCAATATTTG
TTAAAAAAACATTTCAAACA

Product: ResD family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MINILLVDDEKKICEFVKAYLDKEGFVTDEANDGCTAIRYFDLNRYDLVILDRMLPDISGEEVCNHIRNKSDVPIIMLTA
KIDEEDRLGGFKLGCDDYLCKPFNIKELIFRVKSILKRSGKIDFRDIMKFKQGIEINTSSHEVTVRGKKILLTNTEYKIL
LLMASNPQKIYSREELLESVIEEYYEKMDRVIDSHIKNLRQKIEVNSRDCKIIKTIYGVGYRFELQD

Sequences:

>Translated_227_residues
MINILLVDDEKKICEFVKAYLDKEGFVTDEANDGCTAIRYFDLNRYDLVILDRMLPDISGEEVCNHIRNKSDVPIIMLTA
KIDEEDRLGGFKLGCDDYLCKPFNIKELIFRVKSILKRSGKIDFRDIMKFKQGIEINTSSHEVTVRGKKILLTNTEYKIL
LLMASNPQKIYSREELLESVIEEYYEKMDRVIDSHIKNLRQKIEVNSRDCKIIKTIYGVGYRFELQD
>Mature_227_residues
MINILLVDDEKKICEFVKAYLDKEGFVTDEANDGCTAIRYFDLNRYDLVILDRMLPDISGEEVCNHIRNKSDVPIIMLTA
KIDEEDRLGGFKLGCDDYLCKPFNIKELIFRVKSILKRSGKIDFRDIMKFKQGIEINTSSHEVTVRGKKILLTNTEYKIL
LLMASNPQKIYSREELLESVIEEYYEKMDRVIDSHIKNLRQKIEVNSRDCKIIKTIYGVGYRFELQD

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=38.7387387387387, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.7713004484305, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=32.7272727272727, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.920704845815, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=31.4159292035398, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.0810810810811, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.5309734513274, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.4561403508772, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=28.3783783783784, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.4642857142857, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=27.8761061946903, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=25.7510729613734, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=31.304347826087, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26550; Mature: 26550

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINILLVDDEKKICEFVKAYLDKEGFVTDEANDGCTAIRYFDLNRYDLVILDRMLPDISG
CEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHEEEHHHCCCCCH
EEVCNHIRNKSDVPIIMLTAKIDEEDRLGGFKLGCDDYLCKPFNIKELIFRVKSILKRSG
HHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHCC
KIDFRDIMKFKQGIEINTSSHEVTVRGKKILLTNTEYKILLLMASNPQKIYSREELLESV
CCCHHHHHHHHCCCEEECCCCEEEEECCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHH
IEEYYEKMDRVIDSHIKNLRQKIEVNSRDCKIIKTIYGVGYRFELQD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MINILLVDDEKKICEFVKAYLDKEGFVTDEANDGCTAIRYFDLNRYDLVILDRMLPDISG
CEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHEEEHHHCCCCCH
EEVCNHIRNKSDVPIIMLTAKIDEEDRLGGFKLGCDDYLCKPFNIKELIFRVKSILKRSG
HHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHCC
KIDFRDIMKFKQGIEINTSSHEVTVRGKKILLTNTEYKILLLMASNPQKIYSREELLESV
CCCHHHHHHHHCCCEEECCCCEEEEECCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHH
IEEYYEKMDRVIDSHIKNLRQKIEVNSRDCKIIKTIYGVGYRFELQD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]