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The map label for this gene is sigW [H]

Identifier: 187935246

GI number: 187935246

Start: 2304149

End: 2304637

Strand: Reverse

Name: sigW [H]

Synonym: CLL_A2221

Alternate gene names: 187935246

Gene position: 2304637-2304149 (Counterclockwise)

Preceding gene: 187934834

Following gene: 187932941

Centisome position: 60.64

GC content: 24.74

Gene sequence:

>489_bases
ATGGGTAATTCGCTATATATAGATGAAGATATCTCACAAGATTTAGACAAATATGGGGATATGATATTAAGACTTGGATA
TTCATATATGAAAAATATACATGATGCTGAAGATATATTACAAGAAGTTTTACTTAAATTAATTCAGGGTACAAATGAAT
TTGAAAATGAAGAACATAAAAAAGCATGGCTTATATGTGTAAGTAGAAATATTTGTAAAAATAAATTAAAATCTTCTTGG
TTTAAAAAAAGAGAAGAGTTTCAAGAACTTCCATACTATGATAACTATTTAAATCATGATGTTTTTGAGGCTGTTATGAA
GTTACCTACTAAATATAGAGAGGTTATACATTTATTTTATTATGAAGATTATTCTACAATTCAAATTTCAAATTTAATTA
ATAAAAAGGAATCTACAGTACGATCATTATTGCATAGAGCTAGAAATATACTAAAAGACAAATTGAAGGAGGATTATGAT
TTTGAGTAA

Upstream 100 bases:

>100_bases
ATAGTATAAAAGATAATTATAGATAAATGAAAAAAATTTCATATTAATGCAACATTTTATGTTCTTTGATTGTTTTATAA
GTGAAGGGGGAAGCTACCTT

Downstream 100 bases:

>100_bases
GAATTATAAAAAGACTATGGATAAAATTACTGTAGATGATGAAATGAGAAAAAGAATATTAAATAATATAGATTCTATAA
AGCAAGAAAATACAAAAGAC

Product: RNA polymerase sigma-70 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MGNSLYIDEDISQDLDKYGDMILRLGYSYMKNIHDAEDILQEVLLKLIQGTNEFENEEHKKAWLICVSRNICKNKLKSSW
FKKREEFQELPYYDNYLNHDVFEAVMKLPTKYREVIHLFYYEDYSTIQISNLINKKESTVRSLLHRARNILKDKLKEDYD
FE

Sequences:

>Translated_162_residues
MGNSLYIDEDISQDLDKYGDMILRLGYSYMKNIHDAEDILQEVLLKLIQGTNEFENEEHKKAWLICVSRNICKNKLKSSW
FKKREEFQELPYYDNYLNHDVFEAVMKLPTKYREVIHLFYYEDYSTIQISNLINKKESTVRSLLHRARNILKDKLKEDYD
FE
>Mature_161_residues
GNSLYIDEDISQDLDKYGDMILRLGYSYMKNIHDAEDILQEVLLKLIQGTNEFENEEHKKAWLICVSRNICKNKLKSSWF
KKREEFQELPYYDNYLNHDVFEAVMKLPTKYREVIHLFYYEDYSTIQISNLINKKESTVRSLLHRARNILKDKLKEDYDF
E

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19577; Mature: 19445

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSLYIDEDISQDLDKYGDMILRLGYSYMKNIHDAEDILQEVLLKLIQGTNEFENEEHK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
KAWLICVSRNICKNKLKSSWFKKREEFQELPYYDNYLNHDVFEAVMKLPTKYREVIHLFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHH
YEDYSTIQISNLINKKESTVRSLLHRARNILKDKLKEDYDFE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GNSLYIDEDISQDLDKYGDMILRLGYSYMKNIHDAEDILQEVLLKLIQGTNEFENEEHK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
KAWLICVSRNICKNKLKSSWFKKREEFQELPYYDNYLNHDVFEAVMKLPTKYREVIHLFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHH
YEDYSTIQISNLINKKESTVRSLLHRARNILKDKLKEDYDFE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]