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The map label for this gene is pyrK [H]

Identifier: 187935152

GI number: 187935152

Start: 2687807

End: 2688550

Strand: Reverse

Name: pyrK [H]

Synonym: CLL_A2577

Alternate gene names: 187935152

Gene position: 2688550-2687807 (Counterclockwise)

Preceding gene: 187933897

Following gene: 187933348

Centisome position: 70.75

GC content: 32.12

Gene sequence:

>744_bases
ATGAGTACAAATTATAAGAAATCAAAGGTGCTTTCAAATAAAAAAGTAGTTGATAATATATATAAGATGGTTTGTGAAGA
TGACAATATTATAAAAGCAGGACAATTTTACATGCTTAAGATTGATGGTCAAACGTTACTTCCAAGACCTATAAGCATAT
GCGAAAAAGAAGATAATAAAATAACTTTTTTGTATGCAGCAGTAGGAAAAGGAACAGAAGAATTTGCAAAACTTCAAGAG
GGGGATTACATAAATCTTACAGGTGCATTAGGAAATGGATTTGATTTAGATGAATACCTAGGAAAAGTTGCAATTGTTTC
AGGGGGAATTGGAACAGCGCCCATGGTTGAGGTTTGTAAAGTGCTTAGAAGAAATAATAAATATGGGCTTATAGATGTTT
ATGCAGGATTTAGAGATGACATATATTTAACAGAGGAGTTATCAAAATATGCAAATAAAGTAGAGGTAACAACTAATACA
GGAAAACATGGACATAAAGGTTTTGTTACGGATATATTAAAGCCAGAAGAATATGATATTGTGTTATGCTGTGGTCCTGA
AATTATGATGAAAAAAGTTGTTGAGATGTGTAAAGAAAAGAAGGTTAAAGTGTACGTTTCAATGGAAAAACATATGGCAT
GTGGTGTAGGAGCTTGTTTGGTATGTACTTGCAAAACTAAAGGTGGAAATAAGAGAACGTGTAAAGATGGTCCAGTATTT
GATGGATATTATGTGGAATTGTAA

Upstream 100 bases:

>100_bases
AAAACAGAGAAATGGAATTTGCATTATGTGCAAGAGAAGAAGCAATAAAAATGAGAGATGAAATAAAAAGAGCTGTAGAG
AATTTATAAGGAGTGATAAA

Downstream 100 bases:

>100_bases
ATCAGAGGGGAGAATGAAGTTATGTTAAAGGTGAATATAAATGGTGTAGAATTTAAAAATCCAGTTATAGCGGCTTCAGG
AACTTTTGGTTTTGGTGCAG

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSTNYKKSKVLSNKKVVDNIYKMVCEDDNIIKAGQFYMLKIDGQTLLPRPISICEKEDNKITFLYAAVGKGTEEFAKLQE
GDYINLTGALGNGFDLDEYLGKVAIVSGGIGTAPMVEVCKVLRRNNKYGLIDVYAGFRDDIYLTEELSKYANKVEVTTNT
GKHGHKGFVTDILKPEEYDIVLCCGPEIMMKKVVEMCKEKKVKVYVSMEKHMACGVGACLVCTCKTKGGNKRTCKDGPVF
DGYYVEL

Sequences:

>Translated_247_residues
MSTNYKKSKVLSNKKVVDNIYKMVCEDDNIIKAGQFYMLKIDGQTLLPRPISICEKEDNKITFLYAAVGKGTEEFAKLQE
GDYINLTGALGNGFDLDEYLGKVAIVSGGIGTAPMVEVCKVLRRNNKYGLIDVYAGFRDDIYLTEELSKYANKVEVTTNT
GKHGHKGFVTDILKPEEYDIVLCCGPEIMMKKVVEMCKEKKVKVYVSMEKHMACGVGACLVCTCKTKGGNKRTCKDGPVF
DGYYVEL
>Mature_246_residues
STNYKKSKVLSNKKVVDNIYKMVCEDDNIIKAGQFYMLKIDGQTLLPRPISICEKEDNKITFLYAAVGKGTEEFAKLQEG
DYINLTGALGNGFDLDEYLGKVAIVSGGIGTAPMVEVCKVLRRNNKYGLIDVYAGFRDDIYLTEELSKYANKVEVTTNTG
KHGHKGFVTDILKPEEYDIVLCCGPEIMMKKVVEMCKEKKVKVYVSMEKHMACGVGACLVCTCKTKGGNKRTCKDGPVFD
GYYVEL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 27490; Mature: 27359

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNYKKSKVLSNKKVVDNIYKMVCEDDNIIKAGQFYMLKIDGQTLLPRPISICEKEDNK
CCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEECCCCHHHHCCCCCE
ITFLYAAVGKGTEEFAKLQEGDYINLTGALGNGFDLDEYLGKVAIVSGGIGTAPMVEVCK
EEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHCEEEEEECCCCCCHHHHHHH
VLRRNNKYGLIDVYAGFRDDIYLTEELSKYANKVEVTTNTGKHGHKGFVTDILKPEEYDI
HHHCCCCCEEEEEECCCCCCEEEHHHHHHHHCEEEEEECCCCCCCCCHHHHCCCCCCCCE
VLCCGPEIMMKKVVEMCKEKKVKVYVSMEKHMACGVGACLVCTCKTKGGNKRTCKDGPVF
EEEECHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEEEEECCCCCCCCCCCCCEE
DGYYVEL
CCEEEEC
>Mature Secondary Structure 
STNYKKSKVLSNKKVVDNIYKMVCEDDNIIKAGQFYMLKIDGQTLLPRPISICEKEDNK
CCCCCHHHHHCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEECCCCHHHHCCCCCE
ITFLYAAVGKGTEEFAKLQEGDYINLTGALGNGFDLDEYLGKVAIVSGGIGTAPMVEVCK
EEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHCEEEEEECCCCCCHHHHHHH
VLRRNNKYGLIDVYAGFRDDIYLTEELSKYANKVEVTTNTGKHGHKGFVTDILKPEEYDI
HHHCCCCCEEEEEECCCCCCEEEHHHHHHHHCEEEEEECCCCCCCCCHHHHCCCCCCCCE
VLCCGPEIMMKKVVEMCKEKKVKVYVSMEKHMACGVGACLVCTCKTKGGNKRTCKDGPVF
EEEECHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCEEEEEEEECCCCCCCCCCCCCEE
DGYYVEL
CCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]