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The map label for this gene is pyrF [H]

Identifier: 187933897

GI number: 187933897

Start: 2688562

End: 2689434

Strand: Reverse

Name: pyrF [H]

Synonym: CLL_A2578

Alternate gene names: 187933897

Gene position: 2689434-2688562 (Counterclockwise)

Preceding gene: 187933599

Following gene: 187935152

Centisome position: 70.77

GC content: 30.36

Gene sequence:

>873_bases
ATGATGATTAATATAATGGATAAGCTATATGAGAGAGTTGAAAAAAGAGGTGTTGTATGTGTTGGATTAGATACATCGTT
AGATTATGTTCCAGAGCATATAAAAAATAAAAAAACACCAAGTGAAGCTATATTTGAATTTAATAAACAAATTATAGATT
CTACATGTGATATTGCAGCATGTTTTAAAGTACAAATAGCTTATTATGAAGCTTTAGGATTAGATGGATTATTAGCTTAT
AAGAAAACATTAGAATATCTAAGAGAAAAAGATGAAATCATAATAGCTGATATAAAAAGAGGCGACATAGCAGCTACTGC
AAAAATGTATGCAAAGGCTCATTTTGAAGGAGATTTTGAGGCGGATTTTATAACACTAAATCCTTATATGGGAATGGACA
GTATAGAACCATATCTTTCATATTTAGAAAGTGGAAAAAAGGGGATATTTACGTTAGTTAGAACATCAAATAAAGGTGCT
GAAGATATAGAGTATTTAGATACTAATGCAGGTGATAAGGTATATCATGTAGTTGGTGATAAACTTATGAAAATGGGTGA
AAATATGATTTCAAAATGTGGGTATCATCAGTTAGGCGGAGTAATTGGATGTACTCATGTTGAGGAAGGAAAAGAATTAA
GAAAAAGATTTAATTCAATGTTTTTCTTAATACCTGGATATGGAGCACAGGGCGGAAAAGCAGAAGATGTAGCAATGTAC
TTAAATAACGGAAATGGTGGAGTTGTGAATTCATCAAGAGGAATATTACTTGCTTATAAAAAACAAAACAGAGAAATGGA
ATTTGCATTATGTGCAAGAGAAGAAGCAATAAAAATGAGAGATGAAATAAAAAGAGCTGTAGAGAATTTATAA

Upstream 100 bases:

>100_bases
AGTGGCATGTTTATATATGCATAAGCAAAGTGGACTGAGTAATTGAACTTAGGAATGCTACAATAATTTTTAATATATAA
ATATTTGGAGGAGAGTTGCT

Downstream 100 bases:

>100_bases
GGAGTGATAAAATGAGTACAAATTATAAGAAATCAAAGGTGCTTTCAAATAAAAAAGTAGTTGATAATATATATAAGATG
GTTTGTGAAGATGACAATAT

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MMINIMDKLYERVEKRGVVCVGLDTSLDYVPEHIKNKKTPSEAIFEFNKQIIDSTCDIAACFKVQIAYYEALGLDGLLAY
KKTLEYLREKDEIIIADIKRGDIAATAKMYAKAHFEGDFEADFITLNPYMGMDSIEPYLSYLESGKKGIFTLVRTSNKGA
EDIEYLDTNAGDKVYHVVGDKLMKMGENMISKCGYHQLGGVIGCTHVEEGKELRKRFNSMFFLIPGYGAQGGKAEDVAMY
LNNGNGGVVNSSRGILLAYKKQNREMEFALCAREEAIKMRDEIKRAVENL

Sequences:

>Translated_290_residues
MMINIMDKLYERVEKRGVVCVGLDTSLDYVPEHIKNKKTPSEAIFEFNKQIIDSTCDIAACFKVQIAYYEALGLDGLLAY
KKTLEYLREKDEIIIADIKRGDIAATAKMYAKAHFEGDFEADFITLNPYMGMDSIEPYLSYLESGKKGIFTLVRTSNKGA
EDIEYLDTNAGDKVYHVVGDKLMKMGENMISKCGYHQLGGVIGCTHVEEGKELRKRFNSMFFLIPGYGAQGGKAEDVAMY
LNNGNGGVVNSSRGILLAYKKQNREMEFALCAREEAIKMRDEIKRAVENL
>Mature_290_residues
MMINIMDKLYERVEKRGVVCVGLDTSLDYVPEHIKNKKTPSEAIFEFNKQIIDSTCDIAACFKVQIAYYEALGLDGLLAY
KKTLEYLREKDEIIIADIKRGDIAATAKMYAKAHFEGDFEADFITLNPYMGMDSIEPYLSYLESGKKGIFTLVRTSNKGA
EDIEYLDTNAGDKVYHVVGDKLMKMGENMISKCGYHQLGGVIGCTHVEEGKELRKRFNSMFFLIPGYGAQGGKAEDVAMY
LNNGNGGVVNSSRGILLAYKKQNREMEFALCAREEAIKMRDEIKRAVENL

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 32624; Mature: 32624

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMINIMDKLYERVEKRGVVCVGLDTSLDYVPEHIKNKKTPSEAIFEFNKQIIDSTCDIAA
CEEHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHH
CFKVQIAYYEALGLDGLLAYKKTLEYLREKDEIIIADIKRGDIAATAKMYAKAHFEGDFE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
ADFITLNPYMGMDSIEPYLSYLESGKKGIFTLVRTSNKGAEDIEYLDTNAGDKVYHVVGD
EEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEHHHHHH
KLMKMGENMISKCGYHQLGGVIGCTHVEEGKELRKRFNSMFFLIPGYGAQGGKAEDVAMY
HHHHHHHHHHHHCCHHHHCCEEEECCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEE
LNNGNGGVVNSSRGILLAYKKQNREMEFALCAREEAIKMRDEIKRAVENL
EECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMINIMDKLYERVEKRGVVCVGLDTSLDYVPEHIKNKKTPSEAIFEFNKQIIDSTCDIAA
CEEHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHH
CFKVQIAYYEALGLDGLLAYKKTLEYLREKDEIIIADIKRGDIAATAKMYAKAHFEGDFE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
ADFITLNPYMGMDSIEPYLSYLESGKKGIFTLVRTSNKGAEDIEYLDTNAGDKVYHVVGD
EEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEHHHHHH
KLMKMGENMISKCGYHQLGGVIGCTHVEEGKELRKRFNSMFFLIPGYGAQGGKAEDVAMY
HHHHHHHHHHHHCCHHHHCCEEEECCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEE
LNNGNGGVVNSSRGILLAYKKQNREMEFALCAREEAIKMRDEIKRAVENL
EECCCCCEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA