BacMap

Definition	Clostridium botulinum B str. Eklund 17B, complete genome.
Accession	NC_010674
Length	3,800,327

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The map label for this gene is ftsH [H]

Identifier: 187934823

GI number: 187934823

Start: 3446003

End: 3448087

Strand: Reverse

Name: ftsH [H]

Synonym: CLL_A3282

Alternate gene names: 187934823

Gene position: 3448087-3446003 (Counterclockwise)

Preceding gene: 187932527

Following gene: 187935712

Centisome position: 90.73

GC content: 30.7

Gene sequence:

>2085_bases
ATGCAAGGCAACAATAAAAAGAAGAAAAACGGATATATTACAATGGTAATATATTTTTTACTAGTTTTTATGTTCATAAG
TACTGCAAACTATATTAGAGAAGCAGCAACTACAAAACAAATATCATATGATGAATTTTATGAAATGATAGATCAAAGTA
AAATATCACAGGTAGTTATAACAGGAGAAAATTTAATAATTACACCAACAGATAGTAGTGAATTTAAAGGAAAAACTTTA
TATACAGCTAATATTAAGGATGAAAATTTAATAAATAAATTAAGAGAAGCAAACCCTAAAATAAAATTTACAGGAAAAAA
TCCAAAACAAAGTCCAATTATGGATTTTGTACTTAGCTGGATTTTACCAATGTTATTATTTTTTGTTATGTGGAAGTTCC
TATTCTCTAGAATGGGAGGCGGCGGCATGGGCGGTGGCGGCGGAATCATGGGAATTGGAAAAAGTAACGCCAAAGTTTAT
GTAGAAAATGAAATTGGAGTAACGTTTGATGATGTTGCAGGGCAAGAAGAAGCTAAAGAATCATTAAAAGAAGTAATAGA
TTTCTTAAATTGTCCTAAGAGATATACAGAAATAGGTGCAAAATTACCTAAAGGAGCTCTACTTGTAGGACCTCCAGGAA
CAGGTAAAACTCTTATTGCAAAGGCAGTTGCAGGAGAAGCTAAAGTTCCATTTTTCTCACTTTCAGGTTCAAGTTTTGTT
GAAATGTTTGTTGGGGTTGGAGCTTCAAGAGTTAGAGAATTATTTAAAGAAGCAGTAGCTAAAGCACCATGTATAATCTT
TATAGATGAAATAGATGCTATTGGTAAAAGTAGAGATAATCAAATGCAAAGTAATGATGAAAGAGAACAAACATTAAATC
AATTACTTTCTGAAATGGATGGATTTGATTCTTCAAAAGGAATAGTTATACTTGCAGCTACAAATAGACCAGAAATATTA
GATAAAGCTCTTTTAAGACCAGGTAGATTTGATAGAAGAGTAATAGTTGATAGACCTGACTTTAAGGGTAGAGAAGCTAT
TCTTAGAGTTCATGCTAAGAATGTTAATCTAGGAGATGATGTTGATATTGATGAGATAGCAAAGGGAACTCCAGGTGCTG
TAGGAGCAGATCTTGCTAATATTGTTAATGAAGCAGCTTTAAGAGCTGTAAAAAATAGAAGAAAACTTGTGCTTCAAGAA
GATTTAAGAGATGCAGTAGAAGTTATAATTGCAGGTAAAGAAAAGAAAGATAGAATATTATCTAAAAAGGAAAAGGAATT
AGTAGCATTCCATGAGGTAGGTCATGCACTTGTTGCGGCATTATTAGAAGGCTCTGATCCAGTTCATAAAATAACAATAG
TTCCTAGAACAATGGGAGCATTAGGTTATACTATGCAACTTCCTGAAGAAGAAAAATATCTTATTTCTAAAGAAGATTTA
ATGAACCAAATTACAGTGATGCTAGGTGGTAGATCGGCAGAAGAAGAAGTATTTAATGTTGTTTCAACAGGTGCTTCAAA
TGATATCGAAAGAGCAACTCAATCAGCTAGAAGTATGGTTTCAGTATATGGTATGAGTGATAGATTTGATATGATGGCAC
TTGAATCTGTGCAAAATAGATATCTAGATGGAAGAGCAGTTAGACATTGTAGTGAAGAAACATCAACAATGTTAGATGAA
GAAACGCTAAAGATAATAAAAGAAGCTCATGAAAAAGCTAGAAAAATACTTAGAGATAATAGAGATTTATTAGATGAAAT
TTCAAATATTTTATTAGATAAAGAAACTCTTTTTGGGGAAGAATTTATGGAAATGGTTTATGAAAAATACCCAGAAATGA
AAGAAAAGAAAGAAAAAAAATTAAAAGAAAAAGAATTGAAAGATAAAGAACAAAAGGAAAAGCAAAAAAAGAGACAAGAA
GAGTTTGAGAGAATAAAAAAAGAAAATGAAGAAAAAGAAAAATCAGAGTTTTTTAAAACAGTTGGAATAAATGTAAATAA
AGAAATTAATGATTCAACTGAAATTAAAGATGATTTAACTAAGAAGATATCTGAAGATGCACAGCAATTAGAAGATGAAA
AATAA

Upstream 100 bases:

>100_bases
AAACCTTAAAAAGAAAACAAGCAATAAACAAGATGATGAAAAATATGTGGAAATAAGGTTTTTTAGATATTTTCACAAAT
CACATGGAAAGGATGATACA

Downstream 100 bases:

>100_bases
TCTGAGAAATAAATATTTAAGTAAAAATATTTATATCAAGAAAGTTATGTTGCAATGTAAATAACATCTTCAAATAATAA
TTAAAAGAAAAAAACTAGGG

Product: Cell division protease FtsH homolog

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MQGNNKKKKNGYITMVIYFLLVFMFISTANYIREAATTKQISYDEFYEMIDQSKISQVVITGENLIITPTDSSEFKGKTL
YTANIKDENLINKLREANPKIKFTGKNPKQSPIMDFVLSWILPMLLFFVMWKFLFSRMGGGGMGGGGGIMGIGKSNAKVY
VENEIGVTFDDVAGQEEAKESLKEVIDFLNCPKRYTEIGAKLPKGALLVGPPGTGKTLIAKAVAGEAKVPFFSLSGSSFV
EMFVGVGASRVRELFKEAVAKAPCIIFIDEIDAIGKSRDNQMQSNDEREQTLNQLLSEMDGFDSSKGIVILAATNRPEIL
DKALLRPGRFDRRVIVDRPDFKGREAILRVHAKNVNLGDDVDIDEIAKGTPGAVGADLANIVNEAALRAVKNRRKLVLQE
DLRDAVEVIIAGKEKKDRILSKKEKELVAFHEVGHALVAALLEGSDPVHKITIVPRTMGALGYTMQLPEEEKYLISKEDL
MNQITVMLGGRSAEEEVFNVVSTGASNDIERATQSARSMVSVYGMSDRFDMMALESVQNRYLDGRAVRHCSEETSTMLDE
ETLKIIKEAHEKARKILRDNRDLLDEISNILLDKETLFGEEFMEMVYEKYPEMKEKKEKKLKEKELKDKEQKEKQKKRQE
EFERIKKENEEKEKSEFFKTVGINVNKEINDSTEIKDDLTKKISEDAQQLEDEK

Sequences:

>Translated_694_residues
MQGNNKKKKNGYITMVIYFLLVFMFISTANYIREAATTKQISYDEFYEMIDQSKISQVVITGENLIITPTDSSEFKGKTL
YTANIKDENLINKLREANPKIKFTGKNPKQSPIMDFVLSWILPMLLFFVMWKFLFSRMGGGGMGGGGGIMGIGKSNAKVY
VENEIGVTFDDVAGQEEAKESLKEVIDFLNCPKRYTEIGAKLPKGALLVGPPGTGKTLIAKAVAGEAKVPFFSLSGSSFV
EMFVGVGASRVRELFKEAVAKAPCIIFIDEIDAIGKSRDNQMQSNDEREQTLNQLLSEMDGFDSSKGIVILAATNRPEIL
DKALLRPGRFDRRVIVDRPDFKGREAILRVHAKNVNLGDDVDIDEIAKGTPGAVGADLANIVNEAALRAVKNRRKLVLQE
DLRDAVEVIIAGKEKKDRILSKKEKELVAFHEVGHALVAALLEGSDPVHKITIVPRTMGALGYTMQLPEEEKYLISKEDL
MNQITVMLGGRSAEEEVFNVVSTGASNDIERATQSARSMVSVYGMSDRFDMMALESVQNRYLDGRAVRHCSEETSTMLDE
ETLKIIKEAHEKARKILRDNRDLLDEISNILLDKETLFGEEFMEMVYEKYPEMKEKKEKKLKEKELKDKEQKEKQKKRQE
EFERIKKENEEKEKSEFFKTVGINVNKEINDSTEIKDDLTKKISEDAQQLEDEK
>Mature_694_residues
MQGNNKKKKNGYITMVIYFLLVFMFISTANYIREAATTKQISYDEFYEMIDQSKISQVVITGENLIITPTDSSEFKGKTL
YTANIKDENLINKLREANPKIKFTGKNPKQSPIMDFVLSWILPMLLFFVMWKFLFSRMGGGGMGGGGGIMGIGKSNAKVY
VENEIGVTFDDVAGQEEAKESLKEVIDFLNCPKRYTEIGAKLPKGALLVGPPGTGKTLIAKAVAGEAKVPFFSLSGSSFV
EMFVGVGASRVRELFKEAVAKAPCIIFIDEIDAIGKSRDNQMQSNDEREQTLNQLLSEMDGFDSSKGIVILAATNRPEIL
DKALLRPGRFDRRVIVDRPDFKGREAILRVHAKNVNLGDDVDIDEIAKGTPGAVGADLANIVNEAALRAVKNRRKLVLQE
DLRDAVEVIIAGKEKKDRILSKKEKELVAFHEVGHALVAALLEGSDPVHKITIVPRTMGALGYTMQLPEEEKYLISKEDL
MNQITVMLGGRSAEEEVFNVVSTGASNDIERATQSARSMVSVYGMSDRFDMMALESVQNRYLDGRAVRHCSEETSTMLDE
ETLKIIKEAHEKARKILRDNRDLLDEISNILLDKETLFGEEFMEMVYEKYPEMKEKKEKKLKEKELKDKEQKEKQKKRQE
EFERIKKENEEKEKSEFFKTVGINVNKEINDSTEIKDDLTKKISEDAQQLEDEK

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=499, Percent_Identity=44.4889779559118, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507173, Length=475, Percent_Identity=44.8421052631579, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI7657689, Length=444, Percent_Identity=44.5945945945946, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI21327685, Length=444, Percent_Identity=44.5945945945946, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI4506209, Length=252, Percent_Identity=42.4603174603175, Blast_Score=213, Evalue=7e-55,
Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=41.5686274509804, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI24497435, Length=257, Percent_Identity=41.6342412451362, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI24430151, Length=250, Percent_Identity=41.2, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI6005942, Length=240, Percent_Identity=44.5833333333333, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=63.0434782608696, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI89064750, Length=252, Percent_Identity=37.6984126984127, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI5729991, Length=252, Percent_Identity=37.6984126984127, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI21361144, Length=240, Percent_Identity=38.3333333333333, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI24430155, Length=252, Percent_Identity=37.6984126984127, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI157671927, Length=246, Percent_Identity=37.3983739837398, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI45643123, Length=237, Percent_Identity=40.9282700421941, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI45643125, Length=237, Percent_Identity=40.9282700421941, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI4505725, Length=241, Percent_Identity=37.344398340249, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI229577436, Length=262, Percent_Identity=37.7862595419847, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI5901990, Length=247, Percent_Identity=40.4858299595142, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI24497618, Length=258, Percent_Identity=39.1472868217054, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI153792536, Length=256, Percent_Identity=39.0625, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI194018488, Length=231, Percent_Identity=38.0952380952381, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI14149767, Length=301, Percent_Identity=35.5481727574751, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI62177112, Length=301, Percent_Identity=35.5481727574751, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI31377644, Length=264, Percent_Identity=35.9848484848485, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI7019569, Length=231, Percent_Identity=38.961038961039, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI226371754, Length=247, Percent_Identity=36.4372469635627, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI17865802, Length=230, Percent_Identity=40, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI11875211, Length=236, Percent_Identity=37.2881355932203, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI40806170, Length=236, Percent_Identity=37.2881355932203, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI31742536, Length=232, Percent_Identity=34.9137931034483, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI112789543, Length=232, Percent_Identity=34.9137931034483, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI156564401, Length=220, Percent_Identity=37.2727272727273, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI310125280, Length=220, Percent_Identity=36.8181818181818, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310125282, Length=220, Percent_Identity=36.8181818181818, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI64084766, Length=235, Percent_Identity=28.936170212766, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI116292174, Length=226, Percent_Identity=27.8761061946903, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI4757852, Length=164, Percent_Identity=31.0975609756098, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI119964730, Length=164, Percent_Identity=31.0975609756098, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI75677353, Length=205, Percent_Identity=31.219512195122, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI1789568, Length=596, Percent_Identity=44.4630872483221, Blast_Score=508, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71994521, Length=613, Percent_Identity=38.1729200652529, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115534323, Length=452, Percent_Identity=43.141592920354, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17554264, Length=463, Percent_Identity=41.4686825053996, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17563248, Length=257, Percent_Identity=42.8015564202335, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=241, Percent_Identity=45.2282157676349, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25144281, Length=241, Percent_Identity=45.2282157676349, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17554786, Length=241, Percent_Identity=44.3983402489627, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71987364, Length=251, Percent_Identity=39.8406374501992, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=251, Percent_Identity=39.8406374501992, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17532375, Length=245, Percent_Identity=42.8571428571429, Blast_Score=192, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=249, Percent_Identity=43.7751004016064, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=40.4081632653061, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17508701, Length=247, Percent_Identity=38.8663967611336, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17505546, Length=263, Percent_Identity=39.1634980988593, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=38.6178861788618, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17508053, Length=227, Percent_Identity=40.5286343612335, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17537217, Length=244, Percent_Identity=41.3934426229508, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=242, Percent_Identity=38.8429752066116, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=242, Percent_Identity=38.8429752066116, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI133931034, Length=242, Percent_Identity=38.8429752066116, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25153574, Length=239, Percent_Identity=35.1464435146443, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25146157, Length=250, Percent_Identity=40, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=36.6379310344828, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=43.6363636363636, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=43.6363636363636, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI193209502, Length=238, Percent_Identity=34.8739495798319, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI86561515, Length=230, Percent_Identity=39.1304347826087, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17560432, Length=240, Percent_Identity=38.75, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541226, Length=233, Percent_Identity=36.480686695279, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=233, Percent_Identity=36.480686695279, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI133901662, Length=219, Percent_Identity=36.5296803652968, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI133901658, Length=219, Percent_Identity=36.5296803652968, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32563584, Length=231, Percent_Identity=35.9307359307359, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17508421, Length=231, Percent_Identity=35.9307359307359, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323736, Length=509, Percent_Identity=45.5795677799607, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320854, Length=631, Percent_Identity=39.9366085578447, Blast_Score=423, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325281, Length=446, Percent_Identity=45.067264573991, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6322704, Length=266, Percent_Identity=42.1052631578947, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=42.3236514522822, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320077, Length=246, Percent_Identity=43.9024390243902, Blast_Score=196, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6320197, Length=248, Percent_Identity=39.1129032258064, Blast_Score=190, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6324833, Length=242, Percent_Identity=42.9752066115703, Blast_Score=188, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324691, Length=250, Percent_Identity=40, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320602, Length=255, Percent_Identity=41.5686274509804, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323429, Length=226, Percent_Identity=42.4778761061947, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324000, Length=237, Percent_Identity=37.9746835443038, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322994, Length=228, Percent_Identity=42.1052631578947, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=249, Percent_Identity=36.9477911646586, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321709, Length=235, Percent_Identity=37.0212765957447, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325183, Length=266, Percent_Identity=36.8421052631579, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6325431, Length=235, Percent_Identity=37.4468085106383, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321465, Length=249, Percent_Identity=35.7429718875502, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=252, Percent_Identity=35.7142857142857, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=35.6481481481481, Blast_Score=121, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=157, Percent_Identity=32.484076433121, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28574878, Length=508, Percent_Identity=44.6850393700787, Blast_Score=417, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24665814, Length=508, Percent_Identity=44.6850393700787, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24639391, Length=631, Percent_Identity=38.0348652931854, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24658770, Length=504, Percent_Identity=42.2619047619048, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI17137738, Length=252, Percent_Identity=42.8571428571429, Blast_Score=212, Evalue=7e-55,
Organism=Drosophila melanogaster, GI45554047, Length=346, Percent_Identity=37.5722543352601, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24651451, Length=256, Percent_Identity=40.625, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI19920408, Length=257, Percent_Identity=41.6342412451362, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI161076486, Length=245, Percent_Identity=43.265306122449, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17137560, Length=245, Percent_Identity=43.265306122449, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI161076488, Length=245, Percent_Identity=43.265306122449, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24640100, Length=242, Percent_Identity=42.9752066115703, Blast_Score=195, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24649446, Length=248, Percent_Identity=40.7258064516129, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24660075, Length=229, Percent_Identity=43.6681222707424, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281365776, Length=229, Percent_Identity=43.6681222707424, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24663015, Length=260, Percent_Identity=40.7692307692308, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI45552965, Length=229, Percent_Identity=43.6681222707424, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17738151, Length=247, Percent_Identity=39.2712550607287, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19921202, Length=230, Percent_Identity=40.4347826086956, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI18860063, Length=238, Percent_Identity=39.4957983193277, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281361487, Length=238, Percent_Identity=39.0756302521008, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24652279, Length=189, Percent_Identity=42.8571428571429, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI281363136, Length=232, Percent_Identity=40.0862068965517, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI78707192, Length=232, Percent_Identity=40.0862068965517, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24656825, Length=229, Percent_Identity=37.9912663755458, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24656820, Length=229, Percent_Identity=37.9912663755458, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21355121, Length=233, Percent_Identity=36.0515021459227, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI18859657, Length=231, Percent_Identity=39.3939393939394, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24644145, Length=242, Percent_Identity=35.5371900826446, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24581396, Length=234, Percent_Identity=39.3162393162393, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571849, Length=237, Percent_Identity=40.084388185654, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28571847, Length=237, Percent_Identity=40.084388185654, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI281360136, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24644411, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281360144, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360140, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360142, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357333, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360146, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360138, Length=241, Percent_Identity=36.9294605809129, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864540, Length=219, Percent_Identity=36.986301369863, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129423, Length=254, Percent_Identity=32.2834645669291, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573010, Length=219, Percent_Identity=35.6164383561644, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI20129529, Length=258, Percent_Identity=32.5581395348837, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639486, Length=208, Percent_Identity=33.1730769230769, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20129417, Length=154, Percent_Identity=32.4675324675325, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583262, Length=154, Percent_Identity=32.4675324675325, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 78148; Mature: 78148

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00142 ZINC_PROTEASE ; PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGNNKKKKNGYITMVIYFLLVFMFISTANYIREAATTKQISYDEFYEMIDQSKISQVVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEE
TGENLIITPTDSSEFKGKTLYTANIKDENLINKLREANPKIKFTGKNPKQSPIMDFVLSW
ECCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHH
ILPMLLFFVMWKFLFSRMGGGGMGGGGGIMGIGKSNAKVYVENEIGVTFDDVAGQEEAKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEHHHCCHHHHHH
SLKEVIDFLNCPKRYTEIGAKLPKGALLVGPPGTGKTLIAKAVAGEAKVPFFSLSGSSFV
HHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHH
EMFVGVGASRVRELFKEAVAKAPCIIFIDEIDAIGKSRDNQMQSNDEREQTLNQLLSEMD
HHHHHCCHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GFDSSKGIVILAATNRPEILDKALLRPGRFDRRVIVDRPDFKGREAILRVHAKNVNLGDD
CCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHEEECCCCCCCC
VDIDEIAKGTPGAVGADLANIVNEAALRAVKNRRKLVLQEDLRDAVEVIIAGKEKKDRIL
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SKKEKELVAFHEVGHALVAALLEGSDPVHKITIVPRTMGALGYTMQLPEEEKYLISKEDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEEECCCCHHHHHCHHHH
MNQITVMLGGRSAEEEVFNVVSTGASNDIERATQSARSMVSVYGMSDRFDMMALESVQNR
HHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YLDGRAVRHCSEETSTMLDEETLKIIKEAHEKARKILRDNRDLLDEISNILLDKETLFGE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EFMEMVYEKYPEMKEKKEKKLKEKELKDKEQKEKQKKRQEEFERIKKENEEKEKSEFFKT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VGINVNKEINDSTEIKDDLTKKISEDAQQLEDEK
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQGNNKKKKNGYITMVIYFLLVFMFISTANYIREAATTKQISYDEFYEMIDQSKISQVVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEE
TGENLIITPTDSSEFKGKTLYTANIKDENLINKLREANPKIKFTGKNPKQSPIMDFVLSW
ECCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHH
ILPMLLFFVMWKFLFSRMGGGGMGGGGGIMGIGKSNAKVYVENEIGVTFDDVAGQEEAKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEHHHCCHHHHHH
SLKEVIDFLNCPKRYTEIGAKLPKGALLVGPPGTGKTLIAKAVAGEAKVPFFSLSGSSFV
HHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHH
EMFVGVGASRVRELFKEAVAKAPCIIFIDEIDAIGKSRDNQMQSNDEREQTLNQLLSEMD
HHHHHCCHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GFDSSKGIVILAATNRPEILDKALLRPGRFDRRVIVDRPDFKGREAILRVHAKNVNLGDD
CCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHEEECCCCCCCC
VDIDEIAKGTPGAVGADLANIVNEAALRAVKNRRKLVLQEDLRDAVEVIIAGKEKKDRIL
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SKKEKELVAFHEVGHALVAALLEGSDPVHKITIVPRTMGALGYTMQLPEEEKYLISKEDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHCCCEEECCCCHHHHHCHHHH
MNQITVMLGGRSAEEEVFNVVSTGASNDIERATQSARSMVSVYGMSDRFDMMALESVQNR
HHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YLDGRAVRHCSEETSTMLDEETLKIIKEAHEKARKILRDNRDLLDEISNILLDKETLFGE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EFMEMVYEKYPEMKEKKEKKLKEKELKDKEQKEKQKKRQEEFERIKKENEEKEKSEFFKT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VGINVNKEINDSTEIKDDLTKKISEDAQQLEDEK
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA