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The map label for this gene is coaE [H]

Identifier: 187934279

GI number: 187934279

Start: 2758757

End: 2759353

Strand: Reverse

Name: coaE [H]

Synonym: CLL_A2644

Alternate gene names: 187934279

Gene position: 2759353-2758757 (Counterclockwise)

Preceding gene: 187933407

Following gene: 187934284

Centisome position: 72.61

GC content: 27.97

Gene sequence:

>597_bases
ATGATAAAGATAGGGTTAACAGGGGGTATAGGTACTGGAAAAAGTACTATATCAGATATATTTAGAAGTGAAAACTTTAA
TATTATTGATGCAGATGTAATTGCAAGAGAGGTTCTGCAAAAAAATCCTCAAATTTTAGATGTAATTAGAAATGAATTTG
GAACAGGATTTTTTGATTGGAGAGGTGAATTCAGAAGAAGAGAATTTGGAAACCATATATTTAAATTTCCAAAACAAAGA
GTAAAGTATGAATCTATAATTATGCCTTATATAAAAGAAGCAATAAACAATGCAATAAACTCATATGAGAAAAAAGGTGA
TAAAGTAGTAATAATAGATGCACCTACGTTAATTGAAAATAATATGCACGAAGAAATGGATTATGTTGTTCTTGTTTGTG
CTGAAAACTCTGCTCAAATAAAGAGGGTAAGAGACAGAGATAATTTAAGTAAAATAGAAGTAGTAAGTCGCATAAATGCA
CAAATGTCTTTAAATGAAAAGAAGAATTTTGCAAATGTAATTATTGATAATAATGGTGATTTAATAGAAACACAAAAGCA
AGTATATGATTTGATTGACTATATCAATTCACTGTAG

Upstream 100 bases:

>100_bases
ATGGAAAAGGCTATTAAATTAAATGTAGCACTTGATGTAGATTTAAAATACGGTTATACATGGTATGATGCAAAATAAAA
ATGGGAGATGAACTTTTTAA

Downstream 100 bases:

>100_bases
TAAAAAATGACTATGTTTTAAAGGAAAAAATGGTTTGAAACATAGTCGAATTAAGTTGATTTTATAGAATATTAAAACAA
TATGGGATAATAATTTTATA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIKIGLTGGIGTGKSTISDIFRSENFNIIDADVIAREVLQKNPQILDVIRNEFGTGFFDWRGEFRRREFGNHIFKFPKQR
VKYESIIMPYIKEAINNAINSYEKKGDKVVIIDAPTLIENNMHEEMDYVVLVCAENSAQIKRVRDRDNLSKIEVVSRINA
QMSLNEKKNFANVIIDNNGDLIETQKQVYDLIDYINSL

Sequences:

>Translated_198_residues
MIKIGLTGGIGTGKSTISDIFRSENFNIIDADVIAREVLQKNPQILDVIRNEFGTGFFDWRGEFRRREFGNHIFKFPKQR
VKYESIIMPYIKEAINNAINSYEKKGDKVVIIDAPTLIENNMHEEMDYVVLVCAENSAQIKRVRDRDNLSKIEVVSRINA
QMSLNEKKNFANVIIDNNGDLIETQKQVYDLIDYINSL
>Mature_198_residues
MIKIGLTGGIGTGKSTISDIFRSENFNIIDADVIAREVLQKNPQILDVIRNEFGTGFFDWRGEFRRREFGNHIFKFPKQR
VKYESIIMPYIKEAINNAINSYEKKGDKVVIIDAPTLIENNMHEEMDYVVLVCAENSAQIKRVRDRDNLSKIEVVSRINA
QMSLNEKKNFANVIIDNNGDLIETQKQVYDLIDYINSL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=32.8042328042328, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=32.8042328042328, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI110227607, Length=185, Percent_Identity=25.9459459459459, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=185, Percent_Identity=25.9459459459459, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI110227603, Length=185, Percent_Identity=25.9459459459459, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI110227601, Length=185, Percent_Identity=25.9459459459459, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI205277394, Length=185, Percent_Identity=25.9459459459459, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=30.1136363636364, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=35.0515463917526, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24644728, Length=198, Percent_Identity=32.3232323232323, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24658602, Length=190, Percent_Identity=28.4210526315789, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22806; Mature: 22806

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIGLTGGIGTGKSTISDIFRSENFNIIDADVIAREVLQKNPQILDVIRNEFGTGFFDW
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
RGEFRRREFGNHIFKFPKQRVKYESIIMPYIKEAINNAINSYEKKGDKVVIIDAPTLIEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHC
NMHEEMDYVVLVCAENSAQIKRVRDRDNLSKIEVVSRINAQMSLNEKKNFANVIIDNNGD
CHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
LIETQKQVYDLIDYINSL
EEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKIGLTGGIGTGKSTISDIFRSENFNIIDADVIAREVLQKNPQILDVIRNEFGTGFFDW
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
RGEFRRREFGNHIFKFPKQRVKYESIIMPYIKEAINNAINSYEKKGDKVVIIDAPTLIEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHC
NMHEEMDYVVLVCAENSAQIKRVRDRDNLSKIEVVSRINAQMSLNEKKNFANVIIDNNGD
CHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCC
LIETQKQVYDLIDYINSL
EEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]