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The map label for this gene is alr [H]

Identifier: 187933435

GI number: 187933435

Start: 1629442

End: 1630602

Strand: Reverse

Name: alr [H]

Synonym: CLL_A1573

Alternate gene names: 187933435

Gene position: 1630602-1629442 (Counterclockwise)

Preceding gene: 187932887

Following gene: 187935115

Centisome position: 42.91

GC content: 28.17

Gene sequence:

>1161_bases
ATGGAAAAAATAATGAGACCAGTATGGGCAGAAATAGATTTAGATGCAATAGCGTATAATATGAGAAACATAAAGAAATT
AGCGCAAAATAAAGATGTAATTGCAGTTGTAAAGGCTGATTGTTATGGACACGGAGCTTTAGATGTAGTTCCTACACTAC
TTGAAAATGGTGCTTCTAGACTTGCTGTTGCTGTTTTAACTGAAGCAATTGAGCTTAGAAACAACAATATAACTGCTCCA
ATTATGATTTTAGGATACACTCCTGAATATTTATTTGAAGAAGTAGTCAATTATGATATAGAACAAACTGTTTATGATTT
AGAATATGCAAAAAAATTATCACATTTAGCTATAAAATTTAATAAAAAAGCCAAAGTCCATATTGCTATTGATACAGGTA
TGGGTAGAATTGGATTTATTCCAAATGAAAAGGCAATTAAAGATATTAAGAAAATATATAATTTGAAAGGTCTAGATGTA
ATTGGTATATTTACTCACTTCTCAACTTCTGATGAAACTGATAAGGAATATACTAATGAACAATTTAATAAGTTTACATC
TTTTATAGATATGCTTTCAAAGGTTGGAGTTAAAATTCCAATAAAGCATATATCTAATAGTGGTGCTATTATAGATATGC
CAAAAACTTATTTAGACAGCGTAAGGGCTGGTATAATACTATATGGATATTATCCATCTGATGAAATAAATAAAGATAAT
ATTAAGTTAAAACCAGCTCTAACTCTAAAAGCCAGTTTAACACGTGTACAAGAATTAGATATAAACAGTTATATAAGTTA
TGGTAAAACATTTAAAACTGAAAGAAAAAGCATTATAGCAACTTTACCTATTGGATATGCTGATGGATATTCTAGATTGC
TTGCTCCTGGTGCTAAAGTTATAATAAATGGAAAATTCTCTCCAATTATTGGTCGAATATGCATGGATCAATGTATGATT
GATGTTACTGATATTGATGATATTCATGTTGGTGATGAAGTAATAATTCTTGGAGAAGATGGTAATTTAAAATTAACTGC
TAATGATCTTGCTAAATCTATGGGAACAATAAATTATGAAATTCTTTGTATGCTTAAATATAGAATACCTAGAGTTTATA
TGAAAAATGGTAAAATATTTACTGTTAGAAATTATCTTTAA

Upstream 100 bases:

>100_bases
AAACTTAGTGGTTCTTTCATTAAAGTATCTACTTTAATAAAATAATATTATAAAACAAACTATACTTTATTAATATTAAA
TACTAGTGAGGACGATAATT

Downstream 100 bases:

>100_bases
TGCTACAATAGGTTTAAAATTCTATTTTTGTTTCAAAAGTGTGTTTTAATATTTATAAGCAAAACTTTTATATATAAACA
CATATTTAAAACAAAAATAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MEKIMRPVWAEIDLDAIAYNMRNIKKLAQNKDVIAVVKADCYGHGALDVVPTLLENGASRLAVAVLTEAIELRNNNITAP
IMILGYTPEYLFEEVVNYDIEQTVYDLEYAKKLSHLAIKFNKKAKVHIAIDTGMGRIGFIPNEKAIKDIKKIYNLKGLDV
IGIFTHFSTSDETDKEYTNEQFNKFTSFIDMLSKVGVKIPIKHISNSGAIIDMPKTYLDSVRAGIILYGYYPSDEINKDN
IKLKPALTLKASLTRVQELDINSYISYGKTFKTERKSIIATLPIGYADGYSRLLAPGAKVIINGKFSPIIGRICMDQCMI
DVTDIDDIHVGDEVIILGEDGNLKLTANDLAKSMGTINYEILCMLKYRIPRVYMKNGKIFTVRNYL

Sequences:

>Translated_386_residues
MEKIMRPVWAEIDLDAIAYNMRNIKKLAQNKDVIAVVKADCYGHGALDVVPTLLENGASRLAVAVLTEAIELRNNNITAP
IMILGYTPEYLFEEVVNYDIEQTVYDLEYAKKLSHLAIKFNKKAKVHIAIDTGMGRIGFIPNEKAIKDIKKIYNLKGLDV
IGIFTHFSTSDETDKEYTNEQFNKFTSFIDMLSKVGVKIPIKHISNSGAIIDMPKTYLDSVRAGIILYGYYPSDEINKDN
IKLKPALTLKASLTRVQELDINSYISYGKTFKTERKSIIATLPIGYADGYSRLLAPGAKVIINGKFSPIIGRICMDQCMI
DVTDIDDIHVGDEVIILGEDGNLKLTANDLAKSMGTINYEILCMLKYRIPRVYMKNGKIFTVRNYL
>Mature_386_residues
MEKIMRPVWAEIDLDAIAYNMRNIKKLAQNKDVIAVVKADCYGHGALDVVPTLLENGASRLAVAVLTEAIELRNNNITAP
IMILGYTPEYLFEEVVNYDIEQTVYDLEYAKKLSHLAIKFNKKAKVHIAIDTGMGRIGFIPNEKAIKDIKKIYNLKGLDV
IGIFTHFSTSDETDKEYTNEQFNKFTSFIDMLSKVGVKIPIKHISNSGAIIDMPKTYLDSVRAGIILYGYYPSDEINKDN
IKLKPALTLKASLTRVQELDINSYISYGKTFKTERKSIIATLPIGYADGYSRLLAPGAKVIINGKFSPIIGRICMDQCMI
DVTDIDDIHVGDEVIILGEDGNLKLTANDLAKSMGTINYEILCMLKYRIPRVYMKNGKIFTVRNYL

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=366, Percent_Identity=30.6010928961749, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787439, Length=371, Percent_Identity=26.9541778975741, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43373; Mature: 43373

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIMRPVWAEIDLDAIAYNMRNIKKLAQNKDVIAVVKADCYGHGALDVVPTLLENGASR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHH
LAVAVLTEAIELRNNNITAPIMILGYTPEYLFEEVVNYDIEQTVYDLEYAKKLSHLAIKF
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEE
NKKAKVHIAIDTGMGRIGFIPNEKAIKDIKKIYNLKGLDVIGIFTHFSTSDETDKEYTNE
CCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHH
QFNKFTSFIDMLSKVGVKIPIKHISNSGAIIDMPKTYLDSVRAGIILYGYYPSDEINKDN
HHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCHHHHHHHCCCEEEEEECCCCCCCCCC
IKLKPALTLKASLTRVQELDINSYISYGKTFKTERKSIIATLPIGYADGYSRLLAPGAKV
EEEEEEEEEHHHHHHHHHCCHHHHHHCCCHHHHCCCEEEEEECCCCCCCHHHHHCCCCEE
IINGKFSPIIGRICMDQCMIDVTDIDDIHVGDEVIILGEDGNLKLTANDLAKSMGTINYE
EECCCCHHHHHHHHHHHHEEEECCCCCEECCCEEEEEECCCCEEEEHHHHHHHHCCCCEE
ILCMLKYRIPRVYMKNGKIFTVRNYL
EEEEEEECCCEEEEECCCEEEEECCC
>Mature Secondary Structure
MEKIMRPVWAEIDLDAIAYNMRNIKKLAQNKDVIAVVKADCYGHGALDVVPTLLENGASR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHH
LAVAVLTEAIELRNNNITAPIMILGYTPEYLFEEVVNYDIEQTVYDLEYAKKLSHLAIKF
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEE
NKKAKVHIAIDTGMGRIGFIPNEKAIKDIKKIYNLKGLDVIGIFTHFSTSDETDKEYTNE
CCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHH
QFNKFTSFIDMLSKVGVKIPIKHISNSGAIIDMPKTYLDSVRAGIILYGYYPSDEINKDN
HHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCHHHHHHHCCCEEEEEECCCCCCCCCC
IKLKPALTLKASLTRVQELDINSYISYGKTFKTERKSIIATLPIGYADGYSRLLAPGAKV
EEEEEEEEEHHHHHHHHHCCHHHHHHCCCHHHHCCCEEEEEECCCCCCCHHHHHCCCCEE
IINGKFSPIIGRICMDQCMIDVTDIDDIHVGDEVIILGEDGNLKLTANDLAKSMGTINYE
EECCCCHHHHHHHHHHHHEEEECCCCCEECCCEEEEEECCCCEEEEHHHHHHHHCCCCEE
ILCMLKYRIPRVYMKNGKIFTVRNYL
EEEEEEECCCEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA