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The map label for this gene is pocR [H]

Identifier: 187933420

GI number: 187933420

Start: 1933399

End: 1934115

Strand: Reverse

Name: pocR [H]

Synonym: CLL_A1842

Alternate gene names: 187933420

Gene position: 1934115-1933399 (Counterclockwise)

Preceding gene: 187932692

Following gene: 187932402

Centisome position: 50.89

GC content: 23.29

Gene sequence:

>717_bases
ATGTGTAAAGTATTAATAGCTTCTGATGACGCTTTAGAACTTGAAGCTTTAAAAATAATTATATATAAAAAGATAAAAAA
TGTTAGTATTGTTGGATTAGCTTGTAATGGTGATGAAGTAATTAGCATGAATACTAATTTAAATCCCGATATAATTTTTT
TAGATACTATGCTTCCAGGTAAAGATGGGTTTGAAGTAACTAAAATTATAAAGAAAAATTATAAAGAAAAAATAATTGTA
TTAATGAGTATTTATGATAACTTTGAATCTTTACAAAGAGCTTTAAAAGTAAAAGCAGATGACTATTTATTAAAACCAAT
CAAACCAGAAAAGGTTATAGAGATACTAAGTGATTATCTAAAAAATAATGAGTATATGCTCTTAGATGAAAACCTATCTA
ATGAATATAAATTAAATCAAACTTTAAATTATATAGAAAAAAACTTCAAAAAAAACATAACATTGAAAGAAGTAGCAGAA
TATATGAATTATAGTACTACATATTTTAGTAAGAGCTTTAAAAAATATGTAGGTGTTAATTTTAATAAGTACATAACACA
AATAAGAGTACAAGAAGCAAAACGTGTATTAAGAGAAACTAATATTAGCATAAATGATTTAGCATTTGATATGGGATATA
ATGAGCCTAATTATTTTTGCAAAGTATTTAAAAAAGAAGAAGGTATTACTCCATCTGAATATAGAGAAAAAGTATGA

Upstream 100 bases:

>100_bases
TGTATAGGCAAATTTTACTTGCTTTGTATGTCAACACACATTTAAAAATAGATTTTAAAATTAAAAAATAAGGCAAAATG
TAAAGGGGGATAGCATTAGT

Downstream 100 bases:

>100_bases
CATAAAAATATAGTTTACAGTTAAATAATTACTTAAATTTAATAAAAAAACAGCGATTATAATATTTACTGGAAAAATAT
TATAATCAATTGGACACATA

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MCKVLIASDDALELEALKIIIYKKIKNVSIVGLACNGDEVISMNTNLNPDIIFLDTMLPGKDGFEVTKIIKKNYKEKIIV
LMSIYDNFESLQRALKVKADDYLLKPIKPEKVIEILSDYLKNNEYMLLDENLSNEYKLNQTLNYIEKNFKKNITLKEVAE
YMNYSTTYFSKSFKKYVGVNFNKYITQIRVQEAKRVLRETNISINDLAFDMGYNEPNYFCKVFKKEEGITPSEYREKV

Sequences:

>Translated_238_residues
MCKVLIASDDALELEALKIIIYKKIKNVSIVGLACNGDEVISMNTNLNPDIIFLDTMLPGKDGFEVTKIIKKNYKEKIIV
LMSIYDNFESLQRALKVKADDYLLKPIKPEKVIEILSDYLKNNEYMLLDENLSNEYKLNQTLNYIEKNFKKNITLKEVAE
YMNYSTTYFSKSFKKYVGVNFNKYITQIRVQEAKRVLRETNISINDLAFDMGYNEPNYFCKVFKKEEGITPSEYREKV
>Mature_238_residues
MCKVLIASDDALELEALKIIIYKKIKNVSIVGLACNGDEVISMNTNLNPDIIFLDTMLPGKDGFEVTKIIKKNYKEKIIV
LMSIYDNFESLQRALKVKADDYLLKPIKPEKVIEILSDYLKNNEYMLLDENLSNEYKLNQTLNYIEKNFKKNITLKEVAE
YMNYSTTYFSKSFKKYVGVNFNKYITQIRVQEAKRVLRETNISINDLAFDMGYNEPNYFCKVFKKEEGITPSEYREKV

Specific function: Positive regulatory protein of pdu and cob operons [H]

COG id: COG4753

COG function: function code T; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788725, Length=95, Percent_Identity=29.4736842105263, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790391, Length=95, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI171474011, Length=104, Percent_Identity=27.8846153846154, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790339, Length=110, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790559, Length=102, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082052, Length=165, Percent_Identity=30.9090909090909, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787987, Length=123, Percent_Identity=28.4552845528455, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771 [H]

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 27797; Mature: 27797

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKVLIASDDALELEALKIIIYKKIKNVSIVGLACNGDEVISMNTNLNPDIIFLDTMLPG
CEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECCCCCCCEEEEEECCCC
KDGFEVTKIIKKNYKEKIIVLMSIYDNFESLQRALKVKADDYLLKPIKPEKVIEILSDYL
CCCHHHHHHHHHCCHHHEEEEEHHHCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHH
KNNEYMLLDENLSNEYKLNQTLNYIEKNFKKNITLKEVAEYMNYSTTYFSKSFKKYVGVN
CCCCEEEEECCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCC
FNKYITQIRVQEAKRVLRETNISINDLAFDMGYNEPNYFCKVFKKEEGITPSEYREKV
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MCKVLIASDDALELEALKIIIYKKIKNVSIVGLACNGDEVISMNTNLNPDIIFLDTMLPG
CEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECCCCCCCEEEEEECCCC
KDGFEVTKIIKKNYKEKIIVLMSIYDNFESLQRALKVKADDYLLKPIKPEKVIEILSDYL
CCCHHHHHHHHHCCHHHEEEEEHHHCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHH
KNNEYMLLDENLSNEYKLNQTLNYIEKNFKKNITLKEVAEYMNYSTTYFSKSFKKYVGVN
CCCCEEEEECCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCC
FNKYITQIRVQEAKRVLRETNISINDLAFDMGYNEPNYFCKVFKKEEGITPSEYREKV
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034 [H]