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The map label for this gene is lytS [H]

Identifier: 187932692

GI number: 187932692

Start: 1934297

End: 1935508

Strand: Reverse

Name: lytS [H]

Synonym: CLL_A1843

Alternate gene names: 187932692

Gene position: 1935508-1934297 (Counterclockwise)

Preceding gene: 187935184

Following gene: 187933420

Centisome position: 50.93

GC content: 24.59

Gene sequence:

>1212_bases
ATGATTGGTAATAGGAATTTAAATGATATAATTGATATTGATTTATTAAAATCAATACAAGATAGATTAGCTGAAATTAC
TGGACTTGCGTATAATATAGTTGATTTTAAGGGGAATCCAATTAATAATTATTCAAACTTTTGTGATTTTTGTAGTAAAG
TTAGAAATACTAAAGAAGGTATGAAAATATGTTATGACACAAATGCGCATGCAGGACTAGAAGCAGCTATAAGACAAAAA
CCATATGTTTTTAAATGTCCAGCAGGTTTAGTAGATGTTGCTATTCCAATTATTGTAAATGGCAATTATCTTGGCGCAGT
TTTTTTTGGACAAGTTAGAACTAATAAAGATAAGCTTGAGCCAATTAGAAAATCAAATTATTATTCTAAAATGTGTAGAA
ATGATGATAAATTATTAAACGACTTCAATAATACAAAATTTATAGATTATTCTAAGATTGAATCAATATATTCTTTAGTT
AATATAATCGTAAATTTATTGGTTGAAAAATCTGAACTTAGTTCAATTCAGGAAGAATTAAGTTTTAATAATATAAAGCT
TATTAGAGAAAAACAGGAGAGAAAAAAATTAGAAGAAAAACTTAAGTTTTATGAATTGGATTCTTTGGAGACACCTATAA
GTTTTGAATTTATTCTTAATACATTAAACACAATATCTAGTCTTGCATTAATAGAAGATGCTCCTAAAACTCAAGACATG
ATATATTCTTTAACAAAACTATTTAGATATAACTTTAAAAATATTGGTAACTTAGTTTCTATAGGAAAAGCTATAGAAAA
TATCAAAACATACTTAAAGATACAATCAACTAGATTTGGTGATAGAATAAGATATGAGATTAATATAGATGAGAAAATTA
ACGATATTAAAATACCAACTATGATTTTTTTACCATTTATAGAATATTCAATATTAAATGGACTATGTCCTAAGAAAGAT
GGAGGAACTATTTTTATTAAAGGAAAATGCTGTGGAAATAATGCTATTATTTTAATTCAAGACAATGGCATAGGAATTTC
TGAAGATGAATTATTTTCAATATTAAATGGTAAATGCAAAAAAGGTTCTTTAGGTTCAGGTATATATAATGCTAATAATG
TTCTTGTTAAATATTATGGAAAAGAATATAAAGTTAATATAAAAAGCGAACTAAATATAGGGACTATTGTTAGCTTTAAA
CTACCATTATAG

Upstream 100 bases:

>100_bases
TGACAGTATAATTTAATATGGGATAATATTATTAGAATTAACTGTGGAATAAAAAAGATTAAATGTAAAAAATACACTAA
ACAAAAGGTGGTTAATTTAA

Downstream 100 bases:

>100_bases
ATTTTTTTAGTAAAAAGTTGATATATTTATAAGTGTATATGCAAAATAGGGACTTAATAGTTAAAATTATAAGCATTAAA
ATGTATAGGCAAATTTTACT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MIGNRNLNDIIDIDLLKSIQDRLAEITGLAYNIVDFKGNPINNYSNFCDFCSKVRNTKEGMKICYDTNAHAGLEAAIRQK
PYVFKCPAGLVDVAIPIIVNGNYLGAVFFGQVRTNKDKLEPIRKSNYYSKMCRNDDKLLNDFNNTKFIDYSKIESIYSLV
NIIVNLLVEKSELSSIQEELSFNNIKLIREKQERKKLEEKLKFYELDSLETPISFEFILNTLNTISSLALIEDAPKTQDM
IYSLTKLFRYNFKNIGNLVSIGKAIENIKTYLKIQSTRFGDRIRYEINIDEKINDIKIPTMIFLPFIEYSILNGLCPKKD
GGTIFIKGKCCGNNAIILIQDNGIGISEDELFSILNGKCKKGSLGSGIYNANNVLVKYYGKEYKVNIKSELNIGTIVSFK
LPL

Sequences:

>Translated_403_residues
MIGNRNLNDIIDIDLLKSIQDRLAEITGLAYNIVDFKGNPINNYSNFCDFCSKVRNTKEGMKICYDTNAHAGLEAAIRQK
PYVFKCPAGLVDVAIPIIVNGNYLGAVFFGQVRTNKDKLEPIRKSNYYSKMCRNDDKLLNDFNNTKFIDYSKIESIYSLV
NIIVNLLVEKSELSSIQEELSFNNIKLIREKQERKKLEEKLKFYELDSLETPISFEFILNTLNTISSLALIEDAPKTQDM
IYSLTKLFRYNFKNIGNLVSIGKAIENIKTYLKIQSTRFGDRIRYEINIDEKINDIKIPTMIFLPFIEYSILNGLCPKKD
GGTIFIKGKCCGNNAIILIQDNGIGISEDELFSILNGKCKKGSLGSGIYNANNVLVKYYGKEYKVNIKSELNIGTIVSFK
LPL
>Mature_403_residues
MIGNRNLNDIIDIDLLKSIQDRLAEITGLAYNIVDFKGNPINNYSNFCDFCSKVRNTKEGMKICYDTNAHAGLEAAIRQK
PYVFKCPAGLVDVAIPIIVNGNYLGAVFFGQVRTNKDKLEPIRKSNYYSKMCRNDDKLLNDFNNTKFIDYSKIESIYSLV
NIIVNLLVEKSELSSIQEELSFNNIKLIREKQERKKLEEKLKFYELDSLETPISFEFILNTLNTISSLALIEDAPKTQDM
IYSLTKLFRYNFKNIGNLVSIGKAIENIKTYLKIQSTRFGDRIRYEINIDEKINDIKIPTMIFLPFIEYSILNGLCPKKD
GGTIFIKGKCCGNNAIILIQDNGIGISEDELFSILNGKCKKGSLGSGIYNANNVLVKYYGKEYKVNIKSELNIGTIVSFK
LPL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=239, Percent_Identity=27.6150627615063, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788446, Length=217, Percent_Identity=23.963133640553, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45799; Mature: 45799

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGNRNLNDIIDIDLLKSIQDRLAEITGLAYNIVDFKGNPINNYSNFCDFCSKVRNTKEG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
MKICYDTNAHAGLEAAIRQKPYVFKCPAGLVDVAIPIIVNGNYLGAVFFGQVRTNKDKLE
CEEEEECCCCCCHHHHHHCCCEEEECCCCHHHEEEEEEECCCEEEEEEEEEEECCHHHHH
PIRKSNYYSKMCRNDDKLLNDFNNTKFIDYSKIESIYSLVNIIVNLLVEKSELSSIQEEL
HHHHCHHHHHHHCCCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
SFNNIKLIREKQERKKLEEKLKFYELDSLETPISFEFILNTLNTISSLALIEDAPKTQDM
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
IYSLTKLFRYNFKNIGNLVSIGKAIENIKTYLKIQSTRFGDRIRYEINIDEKINDIKIPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCCCCCCH
MIFLPFIEYSILNGLCPKKDGGTIFIKGKCCGNNAIILIQDNGIGISEDELFSILNGKCK
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCC
KGSLGSGIYNANNVLVKYYGKEYKVNIKSELNIGTIVSFKLPL
CCCCCCCEECCCCEEEEEECCEEEEEECCCCCEEEEEEEECCC
>Mature Secondary Structure
MIGNRNLNDIIDIDLLKSIQDRLAEITGLAYNIVDFKGNPINNYSNFCDFCSKVRNTKEG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
MKICYDTNAHAGLEAAIRQKPYVFKCPAGLVDVAIPIIVNGNYLGAVFFGQVRTNKDKLE
CEEEEECCCCCCHHHHHHCCCEEEECCCCHHHEEEEEEECCCEEEEEEEEEEECCHHHHH
PIRKSNYYSKMCRNDDKLLNDFNNTKFIDYSKIESIYSLVNIIVNLLVEKSELSSIQEEL
HHHHCHHHHHHHCCCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
SFNNIKLIREKQERKKLEEKLKFYELDSLETPISFEFILNTLNTISSLALIEDAPKTQDM
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
IYSLTKLFRYNFKNIGNLVSIGKAIENIKTYLKIQSTRFGDRIRYEINIDEKINDIKIPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEECCCCCCCCCCH
MIFLPFIEYSILNGLCPKKDGGTIFIKGKCCGNNAIILIQDNGIGISEDELFSILNGKCK
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCC
KGSLGSGIYNANNVLVKYYGKEYKVNIKSELNIGTIVSFKLPL
CCCCCCCEECCCCEEEEEECCEEEEEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]