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The map label for this gene is ribD [H]

Identifier: 187927760

GI number: 187927760

Start: 704916

End: 706028

Strand: Reverse

Name: ribD [H]

Synonym: Rpic_0664

Alternate gene names: 187927760

Gene position: 706028-704916 (Counterclockwise)

Preceding gene: 187927761

Following gene: 187927759

Centisome position: 17.91

GC content: 67.12

Gene sequence:

>1113_bases
ATGTTCTCCGACTTCGACCACGCCATGATGCAGCGCGCCCTGGCGCTGGCCGAGAAGGGCTTGTTCACCACCACGCCCAA
CCCGCGCGTCGGATGCGTGATCGTGCGAGACGACACCGTCATCGGCGAGGGCTACACGCAACCCGCCGGACAGGACCACG
CTGAAATCCAAGCCATCAAGGATGCTCAGTCGCGCGGCCAGGACGTGCGCGGCGCCACCGCCTATGTGACGCTGGAGCCC
TGCAGCCACTTTGGCCGCACCCCGCCCTGCGCGGATCGTCTCGTCGAAGCGGGGATCACCCGCGTGGTGGCGGCCATGGA
AGATCCAAACCCCGCTGTCTCCGGACGCGGCTTGCAGAAGCTGCGCGATGCCGGGGTCGACGTGCGCTGCGGGCTGCTGG
AGCGGGAGGCGCGTGAGCTGAACATCGGTTTCGTTTCGCGCATGACGCGCGGCACGCCCTGGGTGCGTGTGAAGGTCGGC
GCTTCGCTGGACGGCCGCACCGCGCTGGACAACGGCATCAGCCAGTGGATTACCGAAACCGAGGCGCGCAACGACGGCCA
CCGCTGGCGCGCGCGCGCCTGTGCCATCCTCACCGGTATCGGCACGGTGCGCGAAGACAATCCGCGACTGACCGTGCGCG
CCATCAACACGCCGCGCCAGCCTCGCCGCGTGCTGATCGACTCGGCGCTGGACGTGCCACTCGACGCCCACATCCTCACC
GCAGATGGGCACCACGAGCCGACGCTCATTTTTGCCGCTCAACCCGAAGCTGGCCGCATGCGTGCGTTGAGCGAGCGCGG
CGCGGAGGTCATCCTGCTGCCGAACGCCGCAGGAAAAGTCGATCTGGCCGCAGTCCTGCGCGAACTGGGTCGCCGCGAAA
TCAACGAGCTGCACGTCGAAGCCGGCTTCAAACTCAACGGCTCGCTGCTGCGCGAAGGGCTGGTTGACGAGATCCTCGTC
TATCTGGCACCCAAGGTGCTCGGCTCGGGCCAGGGCATGTTCAATATGGGGCCGCTGCAGACGCTGGAAGGCGCGGCCGA
ATTCTTCTTTCACGATATCTCGCGCATCGGGGGCGATCTCCGCATCCTGGCGCGCCGCAACCCGACGGATTGA

Upstream 100 bases:

>100_bases
AGGCCGCGCCCGCATCTGCGATCCGGCCAAGGACACCAAAACGTGCGGCGCCAGCGCCTCGGCTAACGACGATTAACCCA
AACTCCCGCATTTTTTGCTC

Downstream 100 bases:

>100_bases
TTGCTTATGTTCACCGGAATCGTCGCCGCAGTTGGCCGTATTGAAACCGTCTCGCCGCTTGGCGACAACGCCGATGCCGG
CGTGCGCTTGTCCATCGACG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MFSDFDHAMMQRALALAEKGLFTTTPNPRVGCVIVRDDTVIGEGYTQPAGQDHAEIQAIKDAQSRGQDVRGATAYVTLEP
CSHFGRTPPCADRLVEAGITRVVAAMEDPNPAVSGRGLQKLRDAGVDVRCGLLEREARELNIGFVSRMTRGTPWVRVKVG
ASLDGRTALDNGISQWITETEARNDGHRWRARACAILTGIGTVREDNPRLTVRAINTPRQPRRVLIDSALDVPLDAHILT
ADGHHEPTLIFAAQPEAGRMRALSERGAEVILLPNAAGKVDLAAVLRELGRREINELHVEAGFKLNGSLLREGLVDEILV
YLAPKVLGSGQGMFNMGPLQTLEGAAEFFFHDISRIGGDLRILARRNPTD

Sequences:

>Translated_370_residues
MFSDFDHAMMQRALALAEKGLFTTTPNPRVGCVIVRDDTVIGEGYTQPAGQDHAEIQAIKDAQSRGQDVRGATAYVTLEP
CSHFGRTPPCADRLVEAGITRVVAAMEDPNPAVSGRGLQKLRDAGVDVRCGLLEREARELNIGFVSRMTRGTPWVRVKVG
ASLDGRTALDNGISQWITETEARNDGHRWRARACAILTGIGTVREDNPRLTVRAINTPRQPRRVLIDSALDVPLDAHILT
ADGHHEPTLIFAAQPEAGRMRALSERGAEVILLPNAAGKVDLAAVLRELGRREINELHVEAGFKLNGSLLREGLVDEILV
YLAPKVLGSGQGMFNMGPLQTLEGAAEFFFHDISRIGGDLRILARRNPTD
>Mature_370_residues
MFSDFDHAMMQRALALAEKGLFTTTPNPRVGCVIVRDDTVIGEGYTQPAGQDHAEIQAIKDAQSRGQDVRGATAYVTLEP
CSHFGRTPPCADRLVEAGITRVVAAMEDPNPAVSGRGLQKLRDAGVDVRCGLLEREARELNIGFVSRMTRGTPWVRVKVG
ASLDGRTALDNGISQWITETEARNDGHRWRARACAILTGIGTVREDNPRLTVRAINTPRQPRRVLIDSALDVPLDAHILT
ADGHHEPTLIFAAQPEAGRMRALSERGAEVILLPNAAGKVDLAAVLRELGRREINELHVEAGFKLNGSLLREGLVDEILV
YLAPKVLGSGQGMFNMGPLQTLEGAAEFFFHDISRIGGDLRILARRNPTD

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=47.554347826087, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40295; Mature: 40295

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDFDHAMMQRALALAEKGLFTTTPNPRVGCVIVRDDTVIGEGYTQPAGQDHAEIQAIK
CCCCHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHH
DAQSRGQDVRGATAYVTLEPCSHFGRTPPCADRLVEAGITRVVAAMEDPNPAVSGRGLQK
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LRDAGVDVRCGLLEREARELNIGFVSRMTRGTPWVRVKVGASLDGRTALDNGISQWITET
HHHCCCCEEECHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
EARNDGHRWRARACAILTGIGTVREDNPRLTVRAINTPRQPRRVLIDSALDVPLDAHILT
HCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEE
ADGHHEPTLIFAAQPEAGRMRALSERGAEVILLPNAAGKVDLAAVLRELGRREINELHVE
CCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEE
AGFKLNGSLLREGLVDEILVYLAPKVLGSGQGMFNMGPLQTLEGAAEFFFHDISRIGGDL
CCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
RILARRNPTD
EEEECCCCCC
>Mature Secondary Structure
MFSDFDHAMMQRALALAEKGLFTTTPNPRVGCVIVRDDTVIGEGYTQPAGQDHAEIQAIK
CCCCHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHH
DAQSRGQDVRGATAYVTLEPCSHFGRTPPCADRLVEAGITRVVAAMEDPNPAVSGRGLQK
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LRDAGVDVRCGLLEREARELNIGFVSRMTRGTPWVRVKVGASLDGRTALDNGISQWITET
HHHCCCCEEECHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
EARNDGHRWRARACAILTGIGTVREDNPRLTVRAINTPRQPRRVLIDSALDVPLDAHILT
HCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEE
ADGHHEPTLIFAAQPEAGRMRALSERGAEVILLPNAAGKVDLAAVLRELGRREINELHVE
CCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEE
AGFKLNGSLLREGLVDEILVYLAPKVLGSGQGMFNMGPLQTLEGAAEFFFHDISRIGGDL
CCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
RILARRNPTD
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]