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The map label for this gene is gmhB [H]

Identifier: 187927502

GI number: 187927502

Start: 424077

End: 424655

Strand: Reverse

Name: gmhB [H]

Synonym: Rpic_0399

Alternate gene names: 187927502

Gene position: 424655-424077 (Counterclockwise)

Preceding gene: 187927503

Following gene: 187927501

Centisome position: 10.77

GC content: 67.36

Gene sequence:

>579_bases
ATGCCCCACGTTCCCAAACTGGTGATTCTCGACCGCGATGGCGTCATCAACCGAGACAGCGACCAGTTCATCAAGTCGCC
CGACGAGTGGATCGCGCTCGAGGGCAGCCTGGAAGCCATTGCCGAACTTAACCAGGCGGGCTACCAGGTGGTGGTGGCAA
CCAACCAGTCGGGCATCGGACGCGGCCTGTTTGAGGCCGCCGCGCTCAACGCCATGCACGAGAAGATGTACAAGGCGCTC
GCCACCTACGGCGGGCGCGTCGATGCCGTCTTCTTCTGCCCGCACACCGCCGCCGATGCCTGCGAATGCCGCAAGCCCAA
GTCCGGCATGCTGCGCGAGATTGCACGCCGCTTCGACGTGGACCTCACGGGCGTGCCGGTCGTGGGAGACTCGCTGCGCG
ATCTGCAAGCCGGCGTCGAAGTCGGCGCCGTACCGCACCTCGTACTGACCGGCAAGGGCACCAAGACCCGCGATGCCGGC
GACCTGCCCCCGGGCACCCAAATTCACGAGGACCTGCGTGCGTTTGCGCGTGCGCTGCTGTCCCCCGCGCCCCAGGGCAC
GCCCACGCGCGCCCCTTGA

Upstream 100 bases:

>100_bases
CTGGCGCTGCTGGCTGAACTGCACGGACTGATGAACCGCGTGGCGGACATCTCCAAGCTGGCCGCCTGATCGGCACCCCA
AGCACCGTTCGGAGCCCACC

Downstream 100 bases:

>100_bases
ATTCGCCCCCAATGACTTTTATCCGTTCGCTGCTGTACCTGATTTTCCTGATTGTCTGGACGCCGATCTATGCGGTGGCC
TGCTTCATCGTGTTCCCGTT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPHVPKLVILDRDGVINRDSDQFIKSPDEWIALEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKAL
ATYGGRVDAVFFCPHTAADACECRKPKSGMLREIARRFDVDLTGVPVVGDSLRDLQAGVEVGAVPHLVLTGKGTKTRDAG
DLPPGTQIHEDLRAFARALLSPAPQGTPTRAP

Sequences:

>Translated_192_residues
MPHVPKLVILDRDGVINRDSDQFIKSPDEWIALEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKAL
ATYGGRVDAVFFCPHTAADACECRKPKSGMLREIARRFDVDLTGVPVVGDSLRDLQAGVEVGAVPHLVLTGKGTKTRDAG
DLPPGTQIHEDLRAFARALLSPAPQGTPTRAP
>Mature_191_residues
PHVPKLVILDRDGVINRDSDQFIKSPDEWIALEGSLEAIAELNQAGYQVVVATNQSGIGRGLFEAAALNAMHEKMYKALA
TYGGRVDAVFFCPHTAADACECRKPKSGMLREIARRFDVDLTGVPVVGDSLRDLQAGVEVGAVPHLVLTGKGTKTRDAGD
LPPGTQIHEDLRAFARALLSPAPQGTPTRAP

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=36.6013071895425, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=31.6546762589928, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20553; Mature: 20421

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVPKLVILDRDGVINRDSDQFIKSPDEWIALEGSLEAIAELNQAGYQVVVATNQSGIG
CCCCCEEEEECCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHCCEEEEEEECCCCCC
RGLFEAAALNAMHEKMYKALATYGGRVDAVFFCPHTAADACECRKPKSGMLREIARRFDV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHCC
DLTGVPVVGDSLRDLQAGVEVGAVPHLVLTGKGTKTRDAGDLPPGTQIHEDLRAFARALL
CCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
SPAPQGTPTRAP
CCCCCCCCCCCC
>Mature Secondary Structure 
PHVPKLVILDRDGVINRDSDQFIKSPDEWIALEGSLEAIAELNQAGYQVVVATNQSGIG
CCCCEEEEECCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHCCEEEEEEECCCCCC
RGLFEAAALNAMHEKMYKALATYGGRVDAVFFCPHTAADACECRKPKSGMLREIARRFDV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHCC
DLTGVPVVGDSLRDLQAGVEVGAVPHLVLTGKGTKTRDAGDLPPGTQIHEDLRAFARALL
CCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
SPAPQGTPTRAP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]