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The map label for this gene is plsC [H]

Identifier: 187927501

GI number: 187927501

Start: 423313

End: 424065

Strand: Reverse

Name: plsC [H]

Synonym: Rpic_0398

Alternate gene names: 187927501

Gene position: 424065-423313 (Counterclockwise)

Preceding gene: 187927502

Following gene: 187927500

Centisome position: 10.76

GC content: 62.28

Gene sequence:

>753_bases
ATGACTTTTATCCGTTCGCTGCTGTACCTGATTTTCCTGATTGTCTGGACGCCGATCTATGCGGTGGCCTGCTTCATCGT
GTTCCCGTTCATGAATCCGGCTCGCCGGTTCTGGATGGTGTCGGGCTGGACCAAATCCGCCATCTGGATGGCGCGCTGGC
TGCTCGGCATCCGTTGGCAATACCAGGGCTGGGAGCACATCGAAGAAGCCGTCGCCACCAACAAGCCGGTGGTGCTGCTC
TCCAAGCATCAGTCCGCGTGGGAAACCATGGCCTATGTCGCGACCATGCCTCGGCCGCTGTGCTACGTATTCAAGCGCGA
GCTGCTGTATGTGCCCTTCTTCGGCTGGGCGCTGGGCATGCTCAAAATGGTGCACATCAACCGCAAGGACGGCGCCAACG
CGTTCGCCTCGGTCGCACGTCAGGGCAAGGAACGCATGGCCGAAGGCGCGTGGGTGATCATGTTCCCGGAAGGCACCCGC
ACGCGCTCGGGCGACCCGAAGCCGCGCTACAAGAGCGGCGGTGCGCGTTTTGCCGTGGATACCGGCGCGTGGGTCATCCC
GATCGCCCACAACTCCGGCCGCGTGTGGCCGCGCAATTCGTTCCTGAAGCATCCGGGCCTGATCACGCTGTCGGTCGGTC
CGGCCATCCCGACTGCAGGCAAGACCAGCGACGAACTCAACCGCGAAGTCGAAGCATGGATCGAAGCGGAAATGCGTAGA
ATCGACGCCGATAGCTACCGCGAGCACGCATGA

Upstream 100 bases:

>100_bases
CGGGCACCCAAATTCACGAGGACCTGCGTGCGTTTGCGCGTGCGCTGCTGTCCCCCGCGCCCCAGGGCACGCCCACGCGC
GCCCCTTGAATTCGCCCCCA

Downstream 100 bases:

>100_bases
AACTGCTGCGCCCACCGACTTCGCCCACCACCGCCGACAGCGTCCAGCTTGAGCTGCCGCTGCTCGCACCCGAAGCCTCG
TCGCCCACGCAGCCGCCTGA

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTFIRSLLYLIFLIVWTPIYAVACFIVFPFMNPARRFWMVSGWTKSAIWMARWLLGIRWQYQGWEHIEEAVATNKPVVLL
SKHQSAWETMAYVATMPRPLCYVFKRELLYVPFFGWALGMLKMVHINRKDGANAFASVARQGKERMAEGAWVIMFPEGTR
TRSGDPKPRYKSGGARFAVDTGAWVIPIAHNSGRVWPRNSFLKHPGLITLSVGPAIPTAGKTSDELNREVEAWIEAEMRR
IDADSYREHA

Sequences:

>Translated_250_residues
MTFIRSLLYLIFLIVWTPIYAVACFIVFPFMNPARRFWMVSGWTKSAIWMARWLLGIRWQYQGWEHIEEAVATNKPVVLL
SKHQSAWETMAYVATMPRPLCYVFKRELLYVPFFGWALGMLKMVHINRKDGANAFASVARQGKERMAEGAWVIMFPEGTR
TRSGDPKPRYKSGGARFAVDTGAWVIPIAHNSGRVWPRNSFLKHPGLITLSVGPAIPTAGKTSDELNREVEAWIEAEMRR
IDADSYREHA
>Mature_249_residues
TFIRSLLYLIFLIVWTPIYAVACFIVFPFMNPARRFWMVSGWTKSAIWMARWLLGIRWQYQGWEHIEEAVATNKPVVLLS
KHQSAWETMAYVATMPRPLCYVFKRELLYVPFFGWALGMLKMVHINRKDGANAFASVARQGKERMAEGAWVIMFPEGTRT
RSGDPKPRYKSGGARFAVDTGAWVIPIAHNSGRVWPRNSFLKHPGLITLSVGPAIPTAGKTSDELNREVEAWIEAEMRRI
DADSYREHA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=177, Percent_Identity=28.2485875706215, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5453718, Length=176, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI15100175, Length=176, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=162, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641614, Length=196, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641612, Length=196, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28683; Mature: 28552

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIRSLLYLIFLIVWTPIYAVACFIVFPFMNPARRFWMVSGWTKSAIWMARWLLGIRWQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHHHHHHHHHCCC
YQGWEHIEEAVATNKPVVLLSKHQSAWETMAYVATMPRPLCYVFKRELLYVPFFGWALGM
CCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
LKMVHINRKDGANAFASVARQGKERMAEGAWVIMFPEGTRTRSGDPKPRYKSGGARFAVD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEE
TGAWVIPIAHNSGRVWPRNSFLKHPGLITLSVGPAIPTAGKTSDELNREVEAWIEAEMRR
CCCEEEEEECCCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IDADSYREHA
CCHHHHCCCC
>Mature Secondary Structure 
TFIRSLLYLIFLIVWTPIYAVACFIVFPFMNPARRFWMVSGWTKSAIWMARWLLGIRWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCHHHHHHHHHHHHHCCC
YQGWEHIEEAVATNKPVVLLSKHQSAWETMAYVATMPRPLCYVFKRELLYVPFFGWALGM
CCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
LKMVHINRKDGANAFASVARQGKERMAEGAWVIMFPEGTRTRSGDPKPRYKSGGARFAVD
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEE
TGAWVIPIAHNSGRVWPRNSFLKHPGLITLSVGPAIPTAGKTSDELNREVEAWIEAEMRR
CCCEEEEEECCCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IDADSYREHA
CCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]