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The map label for this gene is yciR [C]

Identifier: 187927489

GI number: 187927489

Start: 410043

End: 412100

Strand: Direct

Name: yciR [C]

Synonym: Rpic_0386

Alternate gene names: 187927489

Gene position: 410043-412100 (Clockwise)

Preceding gene: 187927477

Following gene: 187927494

Centisome position: 10.4

GC content: 65.69

Gene sequence:

>2058_bases
ATGCTCGCCAGCAGTTACAACCCTCTTCTCGTCCTGCTTTCCCTCTTTGTGGCCATCCTGGCGTCGTATACGGCGCTGGA
TATGGCCGGACGGGTCGTCACCGCACAAGGCCGCGCAGCGTTGTGGTGGCTTATCGGCGGCGCGTCGGCCATGGGGCTGG
GCATCTGGTCGATGCACTTTGTCGGCATGCTGGCGCTGAACCTGCCGATCCCGGTTGGATATGACGTGGGCATCACGCTT
GCCTCACTCGCCATCGGCATTGGGGCGTCGACGTTTGCGTTGTGGCTGGTCAGCCGGCGTGAACTGCCTTGGCCGCGCCT
GGTAGGCGGAGCGCTGCTCATGGGGGCCGGCGTGGCGGGCATGCACTACACGGGCATGGCCGCGCTGCGCATGAATCCGG
GCATTCAATACAACCCCGGCAGATTTGGGGTGTCGGTCGTGATTGCCGTGCTGGCATCGGGCGTTGCGCTGTGGATCGCA
TTCCGCCTGCGGCGGCAGTCGCGGCGCGTCCGTGCGCTGCGTGCCGGTTCAGCGGTGGTGATGGGCGTGGCCATTGTCGG
CATGCACTACACGGGCATGTCGGCGGCGGCGTTTCCATTGGGCAGCGTGTGTGGCGCTGCGCATACCGGCGCGAGTGCCG
AATGGCTGGCGCTGGTCATCATCATCGTCACGCTGGCGGTGCTGGCTATCGCGCTCATCATCTCGGTGCTCGACTTGCGC
ATGGAGGCACGCACCGCCTTGCTGGCGAACTCGCTGGCCGCGGCCAACAAGGAGCTGGCCTACCTGGCGCTGCACGACAA
CCTGACCAAACTTTCCAACCGCGTGCTGCTGGAAGACCGTCTGACCCAGGCGATCCGCACCGCCGAACGTGAGAAGCACC
GCTTCGCGCTCATGTTCATGGACCTCGATGGCTTCAAGGCCGTCAACGATGTCTATGGCCACCATGTGGGTGACCTGCTG
CTGATCGACGTTGCCCAGCGCATCGGTGCGCGGGTGCGCCAGCAGGACACCGTGGCGCGTGTCGGCGGCGACGAATTCGT
GGTTCTCGCCTATGTGGACGATCCGGAAGACGCCGGCACCCTGGCCAACGCGCTGCTAGAAGTGGTGCGCGAGCCCTTCA
TGGCCGGCGGTCACGAGCTGCGCGTCTCCACCAGCATCGGCATCGCGATCTACCCTGGCGACGGCGGCAACCAGCACGAC
CTGCTGACCAATGCCGATGCGGCGATGTACCACGCAAAGGGCCTGGGCCGGAACGCCTATAGCTTTTTTGAGCCATCGAT
GAACGCCGACGTGCATCAGCAGTTGCAGCTTGTGCAAGACCTGCGACGCGCGGTCGAGCGGCACGAACTCGTGCTGCATT
ACCAGCCGAAATTCAACGCGCCCAACGGGCCGATCATGGGCGTCGAGGCGCTGGTGCGCTGGCAGCATCCGCAGCGCGGT
CTGGTGCCCGCCGATGAATTCATCCCGCTGGCCGAAAAGACCGGCCTGATCGTGCCGCTGGGCGCGTGGGTGTTGGACGA
AGCCTGTCGCCAGATGGCGCAATGGCAACGCGAGGGGCACAGCGGCTGGAGCGTCGCCGTGAATCTCTCCGCGCTGCAGT
TCGGCCATGCCGCACTCATCGACAGCGTGCGCGATACGCTCGCGCGCCACGCGCTGGACCCGCGCAGCCTGACGCTGGAG
ATTACGGAGTCGACGGCCATGCGCGACGTCGATGCGAGCCTGCAGATCCTGCAGCGGCTCGACGCGATGGGCGTGCGGAT
TTCGATCGACGATTTCGGCACCGGCTATTCCAGCCTGCTGTATCTCAAGCGGTTGCCCGCCAGCGAGCTGAAAATCGACC
GCGGCTTCGTGCGCGACCTGGCGCACGACACGGAAGACGCGGCCATCGTCTCGGCCATCGTGGCGCTGGGCCAGACGCTG
AACCTGCGCATCGTCGCAGAGGGTGTGGAGACGGCCGAGCAGCAGGCGTTTCTCACGCGGCTCGGTTGTCACTCGCTGCA
GGGCTACCTGCTGGGCCGCCCGATGACGGCGGAATCGTTGTCCGCCGCGATGGCGTAA

Upstream 100 bases:

>100_bases
GGGCGGCGCCCCCCGTTAAGACTGACCTGTTTTGCATCCCGGTTGCGACCTCCGCCTGCCGTGGATTGGCCGCATTGGAT
CGGCCTGCCCAGGAGAACCG

Downstream 100 bases:

>100_bases
GCGCCTAGCGCACCGCGAGTTCTGCGTCGAGTGCGGCCAGCTGGGCCGGCGTTCCGACGTTTTCCCAGCGACCGTCGAAG
CGCTCGCCCGTAGCGCGGCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MLASSYNPLLVLLSLFVAILASYTALDMAGRVVTAQGRAALWWLIGGASAMGLGIWSMHFVGMLALNLPIPVGYDVGITL
ASLAIGIGASTFALWLVSRRELPWPRLVGGALLMGAGVAGMHYTGMAALRMNPGIQYNPGRFGVSVVIAVLASGVALWIA
FRLRRQSRRVRALRAGSAVVMGVAIVGMHYTGMSAAAFPLGSVCGAAHTGASAEWLALVIIIVTLAVLAIALIISVLDLR
MEARTALLANSLAAANKELAYLALHDNLTKLSNRVLLEDRLTQAIRTAEREKHRFALMFMDLDGFKAVNDVYGHHVGDLL
LIDVAQRIGARVRQQDTVARVGGDEFVVLAYVDDPEDAGTLANALLEVVREPFMAGGHELRVSTSIGIAIYPGDGGNQHD
LLTNADAAMYHAKGLGRNAYSFFEPSMNADVHQQLQLVQDLRRAVERHELVLHYQPKFNAPNGPIMGVEALVRWQHPQRG
LVPADEFIPLAEKTGLIVPLGAWVLDEACRQMAQWQREGHSGWSVAVNLSALQFGHAALIDSVRDTLARHALDPRSLTLE
ITESTAMRDVDASLQILQRLDAMGVRISIDDFGTGYSSLLYLKRLPASELKIDRGFVRDLAHDTEDAAIVSAIVALGQTL
NLRIVAEGVETAEQQAFLTRLGCHSLQGYLLGRPMTAESLSAAMA

Sequences:

>Translated_685_residues
MLASSYNPLLVLLSLFVAILASYTALDMAGRVVTAQGRAALWWLIGGASAMGLGIWSMHFVGMLALNLPIPVGYDVGITL
ASLAIGIGASTFALWLVSRRELPWPRLVGGALLMGAGVAGMHYTGMAALRMNPGIQYNPGRFGVSVVIAVLASGVALWIA
FRLRRQSRRVRALRAGSAVVMGVAIVGMHYTGMSAAAFPLGSVCGAAHTGASAEWLALVIIIVTLAVLAIALIISVLDLR
MEARTALLANSLAAANKELAYLALHDNLTKLSNRVLLEDRLTQAIRTAEREKHRFALMFMDLDGFKAVNDVYGHHVGDLL
LIDVAQRIGARVRQQDTVARVGGDEFVVLAYVDDPEDAGTLANALLEVVREPFMAGGHELRVSTSIGIAIYPGDGGNQHD
LLTNADAAMYHAKGLGRNAYSFFEPSMNADVHQQLQLVQDLRRAVERHELVLHYQPKFNAPNGPIMGVEALVRWQHPQRG
LVPADEFIPLAEKTGLIVPLGAWVLDEACRQMAQWQREGHSGWSVAVNLSALQFGHAALIDSVRDTLARHALDPRSLTLE
ITESTAMRDVDASLQILQRLDAMGVRISIDDFGTGYSSLLYLKRLPASELKIDRGFVRDLAHDTEDAAIVSAIVALGQTL
NLRIVAEGVETAEQQAFLTRLGCHSLQGYLLGRPMTAESLSAAMA
>Mature_685_residues
MLASSYNPLLVLLSLFVAILASYTALDMAGRVVTAQGRAALWWLIGGASAMGLGIWSMHFVGMLALNLPIPVGYDVGITL
ASLAIGIGASTFALWLVSRRELPWPRLVGGALLMGAGVAGMHYTGMAALRMNPGIQYNPGRFGVSVVIAVLASGVALWIA
FRLRRQSRRVRALRAGSAVVMGVAIVGMHYTGMSAAAFPLGSVCGAAHTGASAEWLALVIIIVTLAVLAIALIISVLDLR
MEARTALLANSLAAANKELAYLALHDNLTKLSNRVLLEDRLTQAIRTAEREKHRFALMFMDLDGFKAVNDVYGHHVGDLL
LIDVAQRIGARVRQQDTVARVGGDEFVVLAYVDDPEDAGTLANALLEVVREPFMAGGHELRVSTSIGIAIYPGDGGNQHD
LLTNADAAMYHAKGLGRNAYSFFEPSMNADVHQQLQLVQDLRRAVERHELVLHYQPKFNAPNGPIMGVEALVRWQHPQRG
LVPADEFIPLAEKTGLIVPLGAWVLDEACRQMAQWQREGHSGWSVAVNLSALQFGHAALIDSVRDTLARHALDPRSLTLE
ITESTAMRDVDASLQILQRLDAMGVRISIDDFGTGYSSLLYLKRLPASELKIDRGFVRDLAHDTEDAAIVSAIVALGQTL
NLRIVAEGVETAEQQAFLTRLGCHSLQGYLLGRPMTAESLSAAMA

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=448, Percent_Identity=40.4017857142857, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI87081921, Length=440, Percent_Identity=35.9090909090909, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI226510982, Length=420, Percent_Identity=32.8571428571429, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI87081980, Length=240, Percent_Identity=39.5833333333333, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=39.6694214876033, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=36.25, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=35.4166666666667, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=32.6446280991736, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786507, Length=265, Percent_Identity=32.8301886792453, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI87082096, Length=475, Percent_Identity=26.7368421052632, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787055, Length=445, Percent_Identity=25.1685393258427, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788849, Length=248, Percent_Identity=31.8548387096774, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788381, Length=394, Percent_Identity=27.9187817258883, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=37.888198757764, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=32.3353293413174, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=34.7305389221557, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=34.1463414634146, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=28.8235294117647, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=35.3658536585366, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787802, Length=280, Percent_Identity=27.8571428571429, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787816, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=33.1325301204819, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=129, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 73838; Mature: 73838

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASSYNPLLVLLSLFVAILASYTALDMAGRVVTAQGRAALWWLIGGASAMGLGIWSMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCHHHHHHHHHHHH
VGMLALNLPIPVGYDVGITLASLAIGIGASTFALWLVSRRELPWPRLVGGALLMGAGVAG
HHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
MHYTGMAALRMNPGIQYNPGRFGVSVVIAVLASGVALWIAFRLRRQSRRVRALRAGSAVV
CCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MGVAIVGMHYTGMSAAAFPLGSVCGAAHTGASAEWLALVIIIVTLAVLAIALIISVLDLR
HHHHHHHHCCCCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEARTALLANSLAAANKELAYLALHDNLTKLSNRVLLEDRLTQAIRTAEREKHRFALMFM
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
DLDGFKAVNDVYGHHVGDLLLIDVAQRIGARVRQQDTVARVGGDEFVVLAYVDDPEDAGT
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHH
LANALLEVVREPFMAGGHELRVSTSIGIAIYPGDGGNQHDLLTNADAAMYHAKGLGRNAY
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCEECCCHHHHHHHCCCCCCH
SFFEPSMNADVHQQLQLVQDLRRAVERHELVLHYQPKFNAPNGPIMGVEALVRWQHPQRG
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
LVPADEFIPLAEKTGLIVPLGAWVLDEACRQMAQWQREGHSGWSVAVNLSALQFGHAALI
CCCHHHCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHH
DSVRDTLARHALDPRSLTLEITESTAMRDVDASLQILQRLDAMGVRISIDDFGTGYSSLL
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
YLKRLPASELKIDRGFVRDLAHDTEDAAIVSAIVALGQTLNLRIVAEGVETAEQQAFLTR
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHH
LGCHSLQGYLLGRPMTAESLSAAMA
HHHHHHCCCEECCCCCHHHHHHHCC
>Mature Secondary Structure
MLASSYNPLLVLLSLFVAILASYTALDMAGRVVTAQGRAALWWLIGGASAMGLGIWSMHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEECCHHHHHHHHHHHH
VGMLALNLPIPVGYDVGITLASLAIGIGASTFALWLVSRRELPWPRLVGGALLMGAGVAG
HHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
MHYTGMAALRMNPGIQYNPGRFGVSVVIAVLASGVALWIAFRLRRQSRRVRALRAGSAVV
CCCCCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MGVAIVGMHYTGMSAAAFPLGSVCGAAHTGASAEWLALVIIIVTLAVLAIALIISVLDLR
HHHHHHHHCCCCCCHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEARTALLANSLAAANKELAYLALHDNLTKLSNRVLLEDRLTQAIRTAEREKHRFALMFM
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
DLDGFKAVNDVYGHHVGDLLLIDVAQRIGARVRQQDTVARVGGDEFVVLAYVDDPEDAGT
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHH
LANALLEVVREPFMAGGHELRVSTSIGIAIYPGDGGNQHDLLTNADAAMYHAKGLGRNAY
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCEECCCHHHHHHHCCCCCCH
SFFEPSMNADVHQQLQLVQDLRRAVERHELVLHYQPKFNAPNGPIMGVEALVRWQHPQRG
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
LVPADEFIPLAEKTGLIVPLGAWVLDEACRQMAQWQREGHSGWSVAVNLSALQFGHAALI
CCCHHHCCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHH
DSVRDTLARHALDPRSLTLEITESTAMRDVDASLQILQRLDAMGVRISIDDFGTGYSSLL
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
YLKRLPASELKIDRGFVRDLAHDTEDAAIVSAIVALGQTLNLRIVAEGVETAEQQAFLTR
HHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHH
LGCHSLQGYLLGRPMTAESLSAAMA
HHHHHHCCCEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]