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The map label for this gene is gpmB [H]

Identifier: 187927477

GI number: 187927477

Start: 397678

End: 398358

Strand: Direct

Name: gpmB [H]

Synonym: Rpic_0374

Alternate gene names: 187927477

Gene position: 397678-398358 (Clockwise)

Preceding gene: 187927476

Following gene: 187927489

Centisome position: 10.09

GC content: 66.81

Gene sequence:

>681_bases
ATGCCACGCGCCGCCGCCATCCCCCTGCCGATGCTGCAGATCACCCACATCGTGCTCATCCGCCACGGCGAGACCGACTG
GAACCGTGAACGGCGCCTGCAAGGCCAACTCGACGTGCCGCTGAACACGCAAGGGCTGGAGCAGGCTGCGCAGTTGGGCA
AGGCACTCGCGCGCGAGCGGTTCGATGCGGTCTATGCGAGCGATCTGTCGCGCGCCAGGCAGACGGCGCGGGCGCTGGCA
GATGAAGTGGGCGTGCCCGTGCGCGACGACGCCGGTTTGCGCGAGCGCTGCTACGGCCAGTTCGAAGGTCTGACCTACGC
CGAAGTTGCCGCACGGCATCCGGACGACTTTGATGCCTGGCAGAACCGCGTGCCCGAATTTGCCCCGCCCGGCGGCGAGA
CCCTCACTGAATTCCACGAACGTGCGGTCGAGACTGCGCTCCGGCTGATCCGTCGCCACCCCGGCGAGCGCATCGCGCTG
GTCAGCCACGGCGGCGTGCTCGATTGCCTGTACCGCCACGCCAACGCCATGACGCTCACCGAGCCGCGCCAGCACGAGCT
GCGCAACGCGAGCATCAACCGGCTTTCATCCGATGGTCATCAACTGACCGTGTTGCAATGGGGGGATGTCGCGCACCTGG
ATTTGCTGGTGCTCGACGAAGTGGACCGCCGTGTTCCTTAA

Upstream 100 bases:

>100_bases
ACGTTCTGGCTGCAGATTGCGCCGCAAGCCGCAGCATCTGTTGCCAAGACTGCCGCGCCGGAAGCGGCCAAATCTGTCTG
ATTCGTCCAGGAACCCTGAG

Downstream 100 bases:

>100_bases
ACCTTCAGCCGGAACGGCGTGAAGTTGGTGTCGCGGTCGTAGTAATCCTCGTTCTCGGCGCGCTTGAGGAAGGCGACGAC
GCGGTAGGTGAGCGGCGTTG

Product: Phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPRAAAIPLPMLQITHIVLIRHGETDWNRERRLQGQLDVPLNTQGLEQAAQLGKALARERFDAVYASDLSRARQTARALA
DEVGVPVRDDAGLRERCYGQFEGLTYAEVAARHPDDFDAWQNRVPEFAPPGGETLTEFHERAVETALRLIRRHPGERIAL
VSHGGVLDCLYRHANAMTLTEPRQHELRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP

Sequences:

>Translated_226_residues
MPRAAAIPLPMLQITHIVLIRHGETDWNRERRLQGQLDVPLNTQGLEQAAQLGKALARERFDAVYASDLSRARQTARALA
DEVGVPVRDDAGLRERCYGQFEGLTYAEVAARHPDDFDAWQNRVPEFAPPGGETLTEFHERAVETALRLIRRHPGERIAL
VSHGGVLDCLYRHANAMTLTEPRQHELRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
>Mature_225_residues
PRAAAIPLPMLQITHIVLIRHGETDWNRERRLQGQLDVPLNTQGLEQAAQLGKALARERFDAVYASDLSRARQTARALAD
EVGVPVRDDAGLRERCYGQFEGLTYAEVAARHPDDFDAWQNRVPEFAPPGGETLTEFHERAVETALRLIRRHPGERIALV
SHGGVLDCLYRHANAMTLTEPRQHELRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=162, Percent_Identity=34.5679012345679, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI50593010, Length=122, Percent_Identity=38.5245901639344, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI4502445, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40353764, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4505753, Length=102, Percent_Identity=41.1764705882353, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI310129614, Length=102, Percent_Identity=41.1764705882353, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1790856, Length=227, Percent_Identity=35.6828193832599, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1786970, Length=202, Percent_Identity=31.1881188118812, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786857, Length=152, Percent_Identity=33.5526315789474, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17510917, Length=156, Percent_Identity=33.974358974359, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993390, Length=156, Percent_Identity=33.974358974359, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324857, Length=164, Percent_Identity=35.3658536585366, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322697, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322306, Length=163, Percent_Identity=31.9018404907975, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646216, Length=133, Percent_Identity=34.5864661654135, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648979, Length=136, Percent_Identity=34.5588235294118, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571815, Length=136, Percent_Identity=34.5588235294118, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571817, Length=136, Percent_Identity=34.5588235294118, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85725270, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725272, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650981, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25435; Mature: 25304

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAAAIPLPMLQITHIVLIRHGETDWNRERRLQGQLDVPLNTQGLEQAAQLGKALARER
CCCCCCCCCHHHHHHHHHEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FDAVYASDLSRARQTARALADEVGVPVRDDAGLRERCYGQFEGLTYAEVAARHPDDFDAW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHH
QNRVPEFAPPGGETLTEFHERAVETALRLIRRHPGERIALVSHGGVLDCLYRHANAMTLT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEECC
EPRQHELRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRAAAIPLPMLQITHIVLIRHGETDWNRERRLQGQLDVPLNTQGLEQAAQLGKALARER
CCCCCCCCHHHHHHHHHEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FDAVYASDLSRARQTARALADEVGVPVRDDAGLRERCYGQFEGLTYAEVAARHPDDFDAW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHH
QNRVPEFAPPGGETLTEFHERAVETALRLIRRHPGERIALVSHGGVLDCLYRHANAMTLT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEECC
EPRQHELRNASINRLSSDGHQLTVLQWGDVAHLDLLVLDEVDRRVP
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA