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The map label for this gene is dtd [H]

Identifier: 187927476

GI number: 187927476

Start: 397146

End: 397658

Strand: Direct

Name: dtd [H]

Synonym: Rpic_0373

Alternate gene names: 187927476

Gene position: 397146-397658 (Clockwise)

Preceding gene: 187927475

Following gene: 187927477

Centisome position: 10.07

GC content: 66.47

Gene sequence:

>513_bases
GTGATTGGGCTGATCCAGCGTGTGTCCGAGGCGGCGGTCCGTGTGGACGGCCGCGTCGTCGGCGAGATCGGCCCGGGTTT
GCTCGCACTGGTCTGTGCAGAACGTGGGGACACCGCCGCCGAGGCCGATCGTCTGCTGGAGAAGCTGCTGAACTATCGCG
TGTTCTCCGACGCGCAGGGCAAGATGAACCTGCCCGTGCGCAACATCGACGGCAACGGGCAGGCGGGCGGCTTGCTGGTC
GTATCGCAGTTCACGCTGGCGGCCGATACCAAGTCTGGCACACGGCCGAGCTTCACGCCCGCTGCTGCGCCGGAAGATGG
GCGCCGCCTGTACGAACACTTCGTGGCGCGCGCGCGTGCCCAGCATCCCATCGTGGCAACCGGCGAGTTTGGCGCCGACA
TGAAGGTGTCGCTCGTCAACGATGGCCCGGTCACGTTCTGGCTGCAGATTGCGCCGCAAGCCGCAGCATCTGTTGCCAAG
ACTGCCGCGCCGGAAGCGGCCAAATCTGTCTGA

Upstream 100 bases:

>100_bases
AGATCGACGGCACCGTCATCAGCGACAAGGGCCTGAAGGTCGACGCCGGCACCTTCGTGATGCAGGTCGGCAAGCGTCGC
TTTGCGCGCGTGGTGCTGAA

Downstream 100 bases:

>100_bases
TTCGTCCAGGAACCCTGAGATGCCACGCGCCGCCGCCATCCCCCTGCCGATGCTGCAGATCACCCACATCGTGCTCATCC
GCCACGGCGAGACCGACTGG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MIGLIQRVSEAAVRVDGRVVGEIGPGLLALVCAERGDTAAEADRLLEKLLNYRVFSDAQGKMNLPVRNIDGNGQAGGLLV
VSQFTLAADTKSGTRPSFTPAAAPEDGRRLYEHFVARARAQHPIVATGEFGADMKVSLVNDGPVTFWLQIAPQAAASVAK
TAAPEAAKSV

Sequences:

>Translated_170_residues
MIGLIQRVSEAAVRVDGRVVGEIGPGLLALVCAERGDTAAEADRLLEKLLNYRVFSDAQGKMNLPVRNIDGNGQAGGLLV
VSQFTLAADTKSGTRPSFTPAAAPEDGRRLYEHFVARARAQHPIVATGEFGADMKVSLVNDGPVTFWLQIAPQAAASVAK
TAAPEAAKSV
>Mature_170_residues
MIGLIQRVSEAAVRVDGRVVGEIGPGLLALVCAERGDTAAEADRLLEKLLNYRVFSDAQGKMNLPVRNIDGNGQAGGLLV
VSQFTLAADTKSGTRPSFTPAAAPEDGRRLYEHFVARARAQHPIVATGEFGADMKVSLVNDGPVTFWLQIAPQAAASVAK
TAAPEAAKSV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=163, Percent_Identity=36.1963190184049, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1790320, Length=151, Percent_Identity=58.9403973509934, Blast_Score=176, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI115533292, Length=145, Percent_Identity=37.9310344827586, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=42.5675675675676, Blast_Score=106, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281361569, Length=155, Percent_Identity=36.7741935483871, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 17838; Mature: 17838

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLIQRVSEAAVRVDGRVVGEIGPGLLALVCAERGDTAAEADRLLEKLLNYRVFSDAQG
CCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCEECCCCCC
KMNLPVRNIDGNGQAGGLLVVSQFTLAADTKSGTRPSFTPAAAPEDGRRLYEHFVARARA
CCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QHPIVATGEFGADMKVSLVNDGPVTFWLQIAPQAAASVAKTAAPEAAKSV
CCCEEEECCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MIGLIQRVSEAAVRVDGRVVGEIGPGLLALVCAERGDTAAEADRLLEKLLNYRVFSDAQG
CCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCEECCCCCC
KMNLPVRNIDGNGQAGGLLVVSQFTLAADTKSGTRPSFTPAAAPEDGRRLYEHFVARARA
CCCCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QHPIVATGEFGADMKVSLVNDGPVTFWLQIAPQAAASVAKTAAPEAAKSV
CCCEEEECCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]