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The map label for this gene is ybhO [H]

Identifier: 187927448

GI number: 187927448

Start: 365753

End: 367021

Strand: Direct

Name: ybhO [H]

Synonym: Rpic_0345

Alternate gene names: 187927448

Gene position: 365753-367021 (Clockwise)

Preceding gene: 187927447

Following gene: 187927449

Centisome position: 9.28

GC content: 67.22

Gene sequence:

>1269_bases
ATGAGGGTCGTGCGCGATGCGGGTCCGCTGCGCTCGGAGTGGCGGCGGGGTAAGCCCCTGCCGGGCAACGACGTCGACCT
GCTGTGCGGTGGCGCCGAGTTCTTCCCCGCACTGATCGAAGCCATCGATGCCGCTCAACGCCGCGTCGCGCTCGAAACCT
ACATCTACACCGACGACGCCACCGCCCACAGCGTGACCGAAGCGCTCGCCCGCGCGGCGCGCCGCGGCGTGGATGTCCAC
CTGACCATCGACGGCTTCGGCACCGGCCTGCTGCCCCCGAGCATCGCGGCGATGCTCGAAACGGCGGGTGTGAACTTGCG
CATCTATCGTCCGGTGCGCGGTTTCCGCCTGCAGCGCCGCCACTTGCGACGGCTGCATCGCAAGATCGCCGTCATCGATG
ACGACGAGGCATTCGTGGGTGGCATCAACATCATCGATGACCTGAATCACGCGCCGTTTAACGACACCGCGCTGGGGCCG
CGTTACGACTTTGCCGTGCGGGTGCGCGGCCCGCTGGTCGCGCAGATTGCGCTGACCGTCGACCGGCTCTGGTGGCAAAT
GGGCGTGCGCGTTGGCATGCGGGAGGTGGGCGTCACGGGCGTCGCCGCCGAGTTTCCGGTGATGACGGATACGCCGCGGC
CACGACATCGCGGAGCATCCGGGCGAGAAAGTGAGCGCGCACCGGGCACCGTGCTGGCTTCGCTGGTGCTGCGTGACAAT
GTCCGTAACCGACGCGCGATCGAACGCGAATATCTGCGCGCGCTGGGTGCGGCGCGGCACGAGGTAATCATCGCCAACGC
GTACTTTTTGCCGGGTGTGCGTTTCATGCGTGCGCTGGCTGCATGTCGACGGCGCGGTGTGCGCGTGCGCCTGTTGCTGC
AGGGGCAGGTCGAATACCGGCTGCAGCACTACGCGACGCGGTCGCTGTATCACATGCTGCTGCGCGACAACGTCGAGATC
CACGAATACACCGCCAGCTTCCTGCACGCCAAGGTGGCCGTGGTGGATGATCGCTGGGCAACGGTCGGCTCGAGCAACAT
CGACCCATTCAGCCTGCTGCTTGCTCGCGAAGCGAACGTAGTGGTGTGGGATTCGACCGTGGCCAACGAACTGCGCGGCG
CGCTGGAAGGCGCCATGGCCCATCACGCACGCCGCGTCCTGGCCGATGCACACGCCGCGCGCCGCTGGTGGTGGCGCCTG
GCAGATTGGTGCGCCTACCGGCTCGTGCGCCTTGGCGTCGTCATCAGCGGGCGCGCAGCACAGTATTAG

Upstream 100 bases:

>100_bases
ACGTACGCGGTTTCGATATTGAACGTGCGCATGCGCTGACCGGCCGCGAATGGGCGCAGCGCTCCGATCACGTTCCCCTG
CTAGCTGAACTGGCGCATCC

Downstream 100 bases:

>100_bases
TGGTACGGACATCTACAAAACAAACAAGACGGAGGAGACATGCAAGTCATCACAGCGGATGAGGCCGCGCGATTGGTGCA
GCCCGGGTGGACGGTGGCAT

Product: phospholipase D/Transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MRVVRDAGPLRSEWRRGKPLPGNDVDLLCGGAEFFPALIEAIDAAQRRVALETYIYTDDATAHSVTEALARAARRGVDVH
LTIDGFGTGLLPPSIAAMLETAGVNLRIYRPVRGFRLQRRHLRRLHRKIAVIDDDEAFVGGINIIDDLNHAPFNDTALGP
RYDFAVRVRGPLVAQIALTVDRLWWQMGVRVGMREVGVTGVAAEFPVMTDTPRPRHRGASGRESERAPGTVLASLVLRDN
VRNRRAIEREYLRALGAARHEVIIANAYFLPGVRFMRALAACRRRGVRVRLLLQGQVEYRLQHYATRSLYHMLLRDNVEI
HEYTASFLHAKVAVVDDRWATVGSSNIDPFSLLLAREANVVVWDSTVANELRGALEGAMAHHARRVLADAHAARRWWWRL
ADWCAYRLVRLGVVISGRAAQY

Sequences:

>Translated_422_residues
MRVVRDAGPLRSEWRRGKPLPGNDVDLLCGGAEFFPALIEAIDAAQRRVALETYIYTDDATAHSVTEALARAARRGVDVH
LTIDGFGTGLLPPSIAAMLETAGVNLRIYRPVRGFRLQRRHLRRLHRKIAVIDDDEAFVGGINIIDDLNHAPFNDTALGP
RYDFAVRVRGPLVAQIALTVDRLWWQMGVRVGMREVGVTGVAAEFPVMTDTPRPRHRGASGRESERAPGTVLASLVLRDN
VRNRRAIEREYLRALGAARHEVIIANAYFLPGVRFMRALAACRRRGVRVRLLLQGQVEYRLQHYATRSLYHMLLRDNVEI
HEYTASFLHAKVAVVDDRWATVGSSNIDPFSLLLAREANVVVWDSTVANELRGALEGAMAHHARRVLADAHAARRWWWRL
ADWCAYRLVRLGVVISGRAAQY
>Mature_422_residues
MRVVRDAGPLRSEWRRGKPLPGNDVDLLCGGAEFFPALIEAIDAAQRRVALETYIYTDDATAHSVTEALARAARRGVDVH
LTIDGFGTGLLPPSIAAMLETAGVNLRIYRPVRGFRLQRRHLRRLHRKIAVIDDDEAFVGGINIIDDLNHAPFNDTALGP
RYDFAVRVRGPLVAQIALTVDRLWWQMGVRVGMREVGVTGVAAEFPVMTDTPRPRHRGASGRESERAPGTVLASLVLRDN
VRNRRAIEREYLRALGAARHEVIIANAYFLPGVRFMRALAACRRRGVRVRLLLQGQVEYRLQHYATRSLYHMLLRDNVEI
HEYTASFLHAKVAVVDDRWATVGSSNIDPFSLLLAREANVVVWDSTVANELRGALEGAMAHHARRVLADAHAARRWWWRL
ADWCAYRLVRLGVVISGRAAQY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=405, Percent_Identity=38.2716049382716, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787502, Length=384, Percent_Identity=25.2604166666667, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 47399; Mature: 47399

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVRDAGPLRSEWRRGKPLPGNDVDLLCGGAEFFPALIEAIDAAQRRVALETYIYTDDA
CCCCCCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEEEEEECCC
TAHSVTEALARAARRGVDVHLTIDGFGTGLLPPSIAAMLETAGVNLRIYRPVRGFRLQRR
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH
HLRRLHRKIAVIDDDEAFVGGINIIDDLNHAPFNDTALGPRYDFAVRVRGPLVAQIALTV
HHHHHHHHEEEEECCCCEECCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
DRLWWQMGVRVGMREVGVTGVAAEFPVMTDTPRPRHRGASGRESERAPGTVLASLVLRDN
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
VRNRRAIEREYLRALGAARHEVIIANAYFLPGVRFMRALAACRRRGVRVRLLLQGQVEYR
CHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHHHHHHHHCCCEEEEEEECHHHHH
LQHYATRSLYHMLLRDNVEIHEYTASFLHAKVAVVDDRWATVGSSNIDPFSLLLAREANV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHHEECCCCE
VVWDSTVANELRGALEGAMAHHARRVLADAHAARRWWWRLADWCAYRLVRLGVVISGRAA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCC
QY
CC
>Mature Secondary Structure
MRVVRDAGPLRSEWRRGKPLPGNDVDLLCGGAEFFPALIEAIDAAQRRVALETYIYTDDA
CCCCCCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEEEEEECCC
TAHSVTEALARAARRGVDVHLTIDGFGTGLLPPSIAAMLETAGVNLRIYRPVRGFRLQRR
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHH
HLRRLHRKIAVIDDDEAFVGGINIIDDLNHAPFNDTALGPRYDFAVRVRGPLVAQIALTV
HHHHHHHHEEEEECCCCEECCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
DRLWWQMGVRVGMREVGVTGVAAEFPVMTDTPRPRHRGASGRESERAPGTVLASLVLRDN
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
VRNRRAIEREYLRALGAARHEVIIANAYFLPGVRFMRALAACRRRGVRVRLLLQGQVEYR
CHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCHHHHHHHHHHHHCCCEEEEEEECHHHHH
LQHYATRSLYHMLLRDNVEIHEYTASFLHAKVAVVDDRWATVGSSNIDPFSLLLAREANV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHHEECCCCE
VVWDSTVANELRGALEGAMAHHARRVLADAHAARRWWWRLADWCAYRLVRLGVVISGRAA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCC
QY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]