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The map label for this gene is acoR [H]

Identifier: 187927390

GI number: 187927390

Start: 304111

End: 306174

Strand: Reverse

Name: acoR [H]

Synonym: Rpic_0285

Alternate gene names: 187927390

Gene position: 306174-304111 (Counterclockwise)

Preceding gene: 187927398

Following gene: 187927387

Centisome position: 7.77

GC content: 61.68

Gene sequence:

>2064_bases
ATGCCTGGCGCCCCCAGCGACCCTGCTCCGACCAATGATGCGCGCGTGAGCCAGGTCTCAAGCGCCTGGAACCTGCTCGA
TACCCCCCTTAGCGGTACATCGTGGCAACGGCAGCATGCCGCCGTCATCGAACAGTCTCATCGACGCTCCACCACCTACG
GCCTTCAAGTCACGGACAACCCCGACTTCAGCGCGCTGAGCAAGGCGGCGCTGTCGCTCGCAATCGAGCAGAACCGTACG
CTGTATGCGTACGCTTTGCCCGTCATGGAAACCCTTTACGAGCAGATCAGTCATCACCACAACATCGTGCTGCTCACTGA
TGCCCAAGGCGTGATCCTCCACGCGCAGGGCGACAAGGACTTCCTGGAGAAGGCCGACCGCGTGGCCTTGTCGCTGGGGG
TGACGTGGTCCGAGCGCCTGCGCGGTACCAATGGCATCGGTACGGCACTTGTAGAAGGGGCGCCCGTCCAGGTCAGCGCC
AATGAGCATTATCTTGGCGTCAACCATGTCCTCAACTGCTCTGCGGTCCCTCTTTTTGACGCATCCGGAAAGGTCACGGG
TGTGCTCAACGTCAGCGGAGATCCGGGAAATTTTCCGGCACACACCATGGCGCTGGTCCGGATGTCAGCGCTACAGATTG
AAAATCAGCTGTTCGCTGCGGCCAATCCCGACTGCATCACGCTGCACTTGCACAGCCGACCCGAATTGATCGGCACGCTC
ATGGAGGGGATGCTGTCTTTTGGGCTGGATGGGCGATATCGCGCGGTCAATCGAAGTGCCCTGTTCCAACTCGGGCTGAC
CCCGTCGGCGTTGGCCGGGCACACGCTGGAATCGCTCCTTGGGCTCAGCGTGCCCGCGCTGTTTGATCACTATCGTTCGG
CAACGCCAGATCCGCTGCGAGTGCATGCTGCCAATGGTATCAGCCTGTATGCCAAGGTCTCGATCCGTCAACGCACCGAT
TGCGGATCGCTGCTACGACCGCTGTCTGCAGACAAGGTGGGACAGGAGGCCGAGTCGCGTGCCGGCACTGCGAGCCCGGT
CCGGGCTCGGGCCACCTCAGGTCTGGGCCAGTTGGACACCGGAGACCCGGAAATCGCAAGAGTGATCAGCAAGCTCAAAA
AATTCAACGGCCGCGATATCCCGACCCTCATCATCGGCGAGACCGGTACCGGCAAAGAGCTCCTGGCCCAGGCTATCCAC
GAGGATTCACCCCGCTGCGCAGGCCCGTTTGTTGCCGTCAACTGTGCGTCGATTCCGGAGACCTTGATCGAATCAGAGCT
CTTCGGGTACGAGGAGGGCGCGTTCACCGGAGCCCGCCGGCGCGGCAGCCTTGGCAAGATCCTGCAGGCAAATGGCGGAA
CGCTGTTCCTCGACGAGATCGGCGATATGCCGCTGACGCTGCAGGCGCGATTGCTGCGTGTGCTGCAAGAGCGCATCGTC
ACCCCCCTGGGCAGCGCCAAGGCGATTCCAGTCAATGTCGCATTGGTTTGCGCAACCCATCGCAATCTGCGCGACATGAT
CGCCCGGGGTACGTTCCGCGACGATCTGTACTACCGATTGAACGGACTATTGGTCAAGCTCCCGCCCTTGCGGCAGCGGC
GTGACTTCGAGGCGGTGCTCAATCGCCTCCTGGTTGGTGAGCACGGTGGTCAGCGCTTCCGGGTTGCCCCCGAAGTCCTG
CGCCTGTTGAAGACATACGACTGGCCGGGGAACATACGCCAACTGGTCAATCTCGTGCGTTCGGCAATGGTCATGGCCGA
GGGCGATGAGATCCAGTTGGATGATCTGCCAGACGATTTCCTGGAAGATGTACGTCATCGGGAGCAACCGGCACAGGAGC
CACCGGCACACGACATGCTGCCGGTATCGGCAGACCAGGCGACGTTGGATCTACTGGAGTCCTCGCTCATCCGGCAGGTG
CTCAAATCGAACGGCGGCAACGTGTCAGCCGCCGCACGCGCACTGGGTGTTTCGCGCAATCGCATCTACCGAAAGCTTCA
GTCGCTTGGCGCCGCACCGACAAGCGATCTGCAGTCGCCGCAACGTGACTCGCGTCCCCTATAG

Upstream 100 bases:

>100_bases
TACGAAGCAAACGCCCTACAAGAAGGGTGCGACCCGCCCATCCAAGCGGGAGCAACCCGACCATCAGTGCGCGCGATCAG
ACGCACAATAGGAGACATAG

Downstream 100 bases:

>100_bases
CGACGAGATGCTCCGCTCTTGCGGTCAGCGCAGACGGACTGCTGAACGCGTTACCCGCCACCGTCATATCGCCACAGAAC
CGCCTGCTCAAGGGCGCGGG

Product: GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MPGAPSDPAPTNDARVSQVSSAWNLLDTPLSGTSWQRQHAAVIEQSHRRSTTYGLQVTDNPDFSALSKAALSLAIEQNRT
LYAYALPVMETLYEQISHHHNIVLLTDAQGVILHAQGDKDFLEKADRVALSLGVTWSERLRGTNGIGTALVEGAPVQVSA
NEHYLGVNHVLNCSAVPLFDASGKVTGVLNVSGDPGNFPAHTMALVRMSALQIENQLFAAANPDCITLHLHSRPELIGTL
MEGMLSFGLDGRYRAVNRSALFQLGLTPSALAGHTLESLLGLSVPALFDHYRSATPDPLRVHAANGISLYAKVSIRQRTD
CGSLLRPLSADKVGQEAESRAGTASPVRARATSGLGQLDTGDPEIARVISKLKKFNGRDIPTLIIGETGTGKELLAQAIH
EDSPRCAGPFVAVNCASIPETLIESELFGYEEGAFTGARRRGSLGKILQANGGTLFLDEIGDMPLTLQARLLRVLQERIV
TPLGSAKAIPVNVALVCATHRNLRDMIARGTFRDDLYYRLNGLLVKLPPLRQRRDFEAVLNRLLVGEHGGQRFRVAPEVL
RLLKTYDWPGNIRQLVNLVRSAMVMAEGDEIQLDDLPDDFLEDVRHREQPAQEPPAHDMLPVSADQATLDLLESSLIRQV
LKSNGGNVSAAARALGVSRNRIYRKLQSLGAAPTSDLQSPQRDSRPL

Sequences:

>Translated_687_residues
MPGAPSDPAPTNDARVSQVSSAWNLLDTPLSGTSWQRQHAAVIEQSHRRSTTYGLQVTDNPDFSALSKAALSLAIEQNRT
LYAYALPVMETLYEQISHHHNIVLLTDAQGVILHAQGDKDFLEKADRVALSLGVTWSERLRGTNGIGTALVEGAPVQVSA
NEHYLGVNHVLNCSAVPLFDASGKVTGVLNVSGDPGNFPAHTMALVRMSALQIENQLFAAANPDCITLHLHSRPELIGTL
MEGMLSFGLDGRYRAVNRSALFQLGLTPSALAGHTLESLLGLSVPALFDHYRSATPDPLRVHAANGISLYAKVSIRQRTD
CGSLLRPLSADKVGQEAESRAGTASPVRARATSGLGQLDTGDPEIARVISKLKKFNGRDIPTLIIGETGTGKELLAQAIH
EDSPRCAGPFVAVNCASIPETLIESELFGYEEGAFTGARRRGSLGKILQANGGTLFLDEIGDMPLTLQARLLRVLQERIV
TPLGSAKAIPVNVALVCATHRNLRDMIARGTFRDDLYYRLNGLLVKLPPLRQRRDFEAVLNRLLVGEHGGQRFRVAPEVL
RLLKTYDWPGNIRQLVNLVRSAMVMAEGDEIQLDDLPDDFLEDVRHREQPAQEPPAHDMLPVSADQATLDLLESSLIRQV
LKSNGGNVSAAARALGVSRNRIYRKLQSLGAAPTSDLQSPQRDSRPL
>Mature_686_residues
PGAPSDPAPTNDARVSQVSSAWNLLDTPLSGTSWQRQHAAVIEQSHRRSTTYGLQVTDNPDFSALSKAALSLAIEQNRTL
YAYALPVMETLYEQISHHHNIVLLTDAQGVILHAQGDKDFLEKADRVALSLGVTWSERLRGTNGIGTALVEGAPVQVSAN
EHYLGVNHVLNCSAVPLFDASGKVTGVLNVSGDPGNFPAHTMALVRMSALQIENQLFAAANPDCITLHLHSRPELIGTLM
EGMLSFGLDGRYRAVNRSALFQLGLTPSALAGHTLESLLGLSVPALFDHYRSATPDPLRVHAANGISLYAKVSIRQRTDC
GSLLRPLSADKVGQEAESRAGTASPVRARATSGLGQLDTGDPEIARVISKLKKFNGRDIPTLIIGETGTGKELLAQAIHE
DSPRCAGPFVAVNCASIPETLIESELFGYEEGAFTGARRRGSLGKILQANGGTLFLDEIGDMPLTLQARLLRVLQERIVT
PLGSAKAIPVNVALVCATHRNLRDMIARGTFRDDLYYRLNGLLVKLPPLRQRRDFEAVLNRLLVGEHGGQRFRVAPEVLR
LLKTYDWPGNIRQLVNLVRSAMVMAEGDEIQLDDLPDDFLEDVRHREQPAQEPPAHDMLPVSADQATLDLLESSLIRQVL
KSNGGNVSAAARALGVSRNRIYRKLQSLGAAPTSDLQSPQRDSRPL

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=370, Percent_Identity=38.6486486486486, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1790299, Length=323, Percent_Identity=42.4148606811146, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1789233, Length=312, Percent_Identity=40.7051282051282, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788905, Length=390, Percent_Identity=37.6923076923077, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=41.2140575079872, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI87082117, Length=327, Percent_Identity=39.1437308868502, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1789087, Length=325, Percent_Identity=39.3846153846154, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1786524, Length=382, Percent_Identity=36.1256544502618, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1787583, Length=335, Percent_Identity=37.0149253731343, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI87082152, Length=337, Percent_Identity=37.6854599406528, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87081858, Length=656, Percent_Identity=24.6951219512195, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=36.1370716510903, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789828, Length=318, Percent_Identity=34.9056603773585, Blast_Score=141, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74476; Mature: 74345

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAPSDPAPTNDARVSQVSSAWNLLDTPLSGTSWQRQHAAVIEQSHRRSTTYGLQVTDN
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
PDFSALSKAALSLAIEQNRTLYAYALPVMETLYEQISHHHNIVLLTDAQGVILHAQGDKD
CCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHH
FLEKADRVALSLGVTWSERLRGTNGIGTALVEGAPVQVSANEHYLGVNHVLNCSAVPLFD
HHHHHHHEEEEECCCHHHHHCCCCCCCHHHCCCCCEEEECCCCEECHHHEECCCCCEEEC
ASGKVTGVLNVSGDPGNFPAHTMALVRMSALQIENQLFAAANPDCITLHLHSRPELIGTL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCHHHHHHH
MEGMLSFGLDGRYRAVNRSALFQLGLTPSALAGHTLESLLGLSVPALFDHYRSATPDPLR
HHHHHHHCCCCCEEEECHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
VHAANGISLYAKVSIRQRTDCGSLLRPLSADKVGQEAESRAGTASPVRARATSGLGQLDT
EEECCCEEEEEEEEECCCCCHHHHHCCCCHHHHCHHHHHCCCCCCCHHHHHHCCCCCCCC
GDPEIARVISKLKKFNGRDIPTLIIGETGTGKELLAQAIHEDSPRCAGPFVAVNCASIPE
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECHHHHH
TLIESELFGYEEGAFTGARRRGSLGKILQANGGTLFLDEIGDMPLTLQARLLRVLQERIV
HHHHHHHCCCCCCCCCCHHHCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
TPLGSAKAIPVNVALVCATHRNLRDMIARGTFRDDLYYRLNGLLVKLPPLRQRRDFEAVL
CCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCHHHHHHEECCEEEECCCCCCCCCHHHHH
NRLLVGEHGGQRFRVAPEVLRLLKTYDWPGNIRQLVNLVRSAMVMAEGDEIQLDDLPDDF
HHHHHCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LEDVRHREQPAQEPPAHDMLPVSADQATLDLLESSLIRQVLKSNGGNVSAAARALGVSRN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHH
RIYRKLQSLGAAPTSDLQSPQRDSRPL
HHHHHHHHHCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
PGAPSDPAPTNDARVSQVSSAWNLLDTPLSGTSWQRQHAAVIEQSHRRSTTYGLQVTDN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
PDFSALSKAALSLAIEQNRTLYAYALPVMETLYEQISHHHNIVLLTDAQGVILHAQGDKD
CCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCHH
FLEKADRVALSLGVTWSERLRGTNGIGTALVEGAPVQVSANEHYLGVNHVLNCSAVPLFD
HHHHHHHEEEEECCCHHHHHCCCCCCCHHHCCCCCEEEECCCCEECHHHEECCCCCEEEC
ASGKVTGVLNVSGDPGNFPAHTMALVRMSALQIENQLFAAANPDCITLHLHSRPELIGTL
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCHHHHHHH
MEGMLSFGLDGRYRAVNRSALFQLGLTPSALAGHTLESLLGLSVPALFDHYRSATPDPLR
HHHHHHHCCCCCEEEECHHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEE
VHAANGISLYAKVSIRQRTDCGSLLRPLSADKVGQEAESRAGTASPVRARATSGLGQLDT
EEECCCEEEEEEEEECCCCCHHHHHCCCCHHHHCHHHHHCCCCCCCHHHHHHCCCCCCCC
GDPEIARVISKLKKFNGRDIPTLIIGETGTGKELLAQAIHEDSPRCAGPFVAVNCASIPE
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECHHHHH
TLIESELFGYEEGAFTGARRRGSLGKILQANGGTLFLDEIGDMPLTLQARLLRVLQERIV
HHHHHHHCCCCCCCCCCHHHCCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
TPLGSAKAIPVNVALVCATHRNLRDMIARGTFRDDLYYRLNGLLVKLPPLRQRRDFEAVL
CCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCHHHHHHEECCEEEECCCCCCCCCHHHHH
NRLLVGEHGGQRFRVAPEVLRLLKTYDWPGNIRQLVNLVRSAMVMAEGDEIQLDDLPDDF
HHHHHCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LEDVRHREQPAQEPPAHDMLPVSADQATLDLLESSLIRQVLKSNGGNVSAAARALGVSRN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHH
RIYRKLQSLGAAPTSDLQSPQRDSRPL
HHHHHHHHHCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]