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The map label for this gene is bioC [C]

Identifier: 187927324

GI number: 187927324

Start: 232205

End: 233146

Strand: Direct

Name: bioC [C]

Synonym: Rpic_0216

Alternate gene names: 187927324

Gene position: 232205-233146 (Clockwise)

Preceding gene: 187927321

Following gene: 187927325

Centisome position: 5.89

GC content: 65.82

Gene sequence:

>942_bases
ATGTCTGATCCCGTCCTTGCTCGCCCTGCCGCCTTGCGGCGCGCCTTCGATCGCCGCGCCGCGCGTTTCGCCGACGTGGA
CTTTTTGCTGCGCGAAGTGGGCAGTCGCATGCAGGACCGGCTGTCCTACATCAAGGCCACGCCTGTCCGCGCGCTGGATT
TGGGTTGCGGTCTGGGACAAGGCTTGGCGGTGCTGCGTGCGCAATATCCGGATGCGCAGATCTGCGGGGTGGACTGGTCG
TCCGCCATGCTGGCGCAAGCGCAGAAACTCGACCCGCAGCGCACTGACGCCGGATGGCTCGGCAGGCTGCTGAAGAAGCG
GCCGGTCTTTGACTTTGCCCAGGCGGACTTTCGCGCTTTGCCCTTTGCTGGCGCGTCGTTCGACCTGCTGTGGTCGAACC
TGGCGCTGCACTGGGACCCGGCGCCGCACGCGATCTTTCCAGAGTGGCACCGCATCACCACGGAAGGCGGCCTGCTGATG
TTCAGCCTGTTCGGTCCGGATACCCTGCGCGAGCTGCGCAGCGCCCTGGCCGGCATCGACGCGGGCGTCCATACGCTGCG
CTTTGTCGATATGCACGACATTGGCGACATGCTGGTGCACAGCCGCTGGTCTACACCCGTCATGGACATGGAGCAGATCA
CGATCACCTACGAAACGCCGCAGGCGTTGCTGGCCGATGTGCATTTGCTGGGCGGCATGGCCGGCTTGACGGACGAAGCC
GGCCACAGTCTCGCGGGCGCCGGCCTGCACACGCCCCGCTGGCGCCAGCGACTATTCGACGCATTCGACGCGCAACGCAA
TCCCGATGGGCTGATTCCGCTGACCTTCGAAATCGTCTACGGCCACGCCTGGAAGCTTGCGCCCACCCAGCGGCAGGCGC
TGGACGAGCAGGGAAGGGCGATGATCCCGATCGATCAGATCGGTCGCAAACCGCGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCTATCCAAGCCGATTTGCGGCTTCTGCGCTATCAGACGGCGCCTCAAACTGCGGGCCGGTATACTTGGCGACCGCAG
TGTTCCGTCCCGCCTTGTCG

Downstream 100 bases:

>100_bases
AGCGCTTTTAGTGCGGGAACGGCATTGGCTCGGCCTTGTCAAGCCGGGACTTGCATAAAGGCGCTTTACCTTGTTCGGGG
TCAATCGCGGCCATATAATG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: Biotin Synthesis Protein BioC; Methyltransferase Type; Biotin Synthesis Protein; Methyltransferase; SAM-Dependent Methyltransferase; Biotin Synthesis Protein Bioc; Biotin Synthase BioC; UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase; Biotin Biosynthesis-Like Protein; LOW QUALITY PROTEIN Biotin Synthesis Protein; S-Adenosyl-L-Methionine-Dependent Methyltransferases; Methyltransferase Domain-Containing Protein; BIOTIN SYNSIS METHYLTRANSFERASE BioC; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Biotin Biosynthesis Methyltransferase BioC; Biotin Biosynthesis Protein Bioc; SAM-Dependent Methyltransferase Protein

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSDPVLARPAALRRAFDRRAARFADVDFLLREVGSRMQDRLSYIKATPVRALDLGCGLGQGLAVLRAQYPDAQICGVDWS
SAMLAQAQKLDPQRTDAGWLGRLLKKRPVFDFAQADFRALPFAGASFDLLWSNLALHWDPAPHAIFPEWHRITTEGGLLM
FSLFGPDTLRELRSALAGIDAGVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYETPQALLADVHLLGGMAGLTDEA
GHSLAGAGLHTPRWRQRLFDAFDAQRNPDGLIPLTFEIVYGHAWKLAPTQRQALDEQGRAMIPIDQIGRKPRA

Sequences:

>Translated_313_residues
MSDPVLARPAALRRAFDRRAARFADVDFLLREVGSRMQDRLSYIKATPVRALDLGCGLGQGLAVLRAQYPDAQICGVDWS
SAMLAQAQKLDPQRTDAGWLGRLLKKRPVFDFAQADFRALPFAGASFDLLWSNLALHWDPAPHAIFPEWHRITTEGGLLM
FSLFGPDTLRELRSALAGIDAGVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYETPQALLADVHLLGGMAGLTDEA
GHSLAGAGLHTPRWRQRLFDAFDAQRNPDGLIPLTFEIVYGHAWKLAPTQRQALDEQGRAMIPIDQIGRKPRA
>Mature_312_residues
SDPVLARPAALRRAFDRRAARFADVDFLLREVGSRMQDRLSYIKATPVRALDLGCGLGQGLAVLRAQYPDAQICGVDWSS
AMLAQAQKLDPQRTDAGWLGRLLKKRPVFDFAQADFRALPFAGASFDLLWSNLALHWDPAPHAIFPEWHRITTEGGLLMF
SLFGPDTLRELRSALAGIDAGVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYETPQALLADVHLLGGMAGLTDEAG
HSLAGAGLHTPRWRQRLFDAFDAQRNPDGLIPLTFEIVYGHAWKLAPTQRQALDEQGRAMIPIDQIGRKPRA

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=295, Percent_Identity=28.135593220339, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535003, Length=308, Percent_Identity=25.6493506493506, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19922210, Length=307, Percent_Identity=30.6188925081433, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34809; Mature: 34678

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPVLARPAALRRAFDRRAARFADVDFLLREVGSRMQDRLSYIKATPVRALDLGCGLGQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
GLAVLRAQYPDAQICGVDWSSAMLAQAQKLDPQRTDAGWLGRLLKKRPVFDFAQADFRAL
CHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCHHCC
PFAGASFDLLWSNLALHWDPAPHAIFPEWHRITTEGGLLMFSLFGPDTLRELRSALAGID
CCCCCHHHHHHHCCEEEECCCCCCCCCCHHEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AGVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYETPQALLADVHLLGGMAGLTDEA
CCHHHEEEECHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCC
GHSLAGAGLHTPRWRQRLFDAFDAQRNPDGLIPLTFEIVYGHAWKLAPTQRQALDEQGRA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEEECCCHHHHHHHHCCCE
MIPIDQIGRKPRA
EECHHHCCCCCCC
>Mature Secondary Structure 
SDPVLARPAALRRAFDRRAARFADVDFLLREVGSRMQDRLSYIKATPVRALDLGCGLGQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
GLAVLRAQYPDAQICGVDWSSAMLAQAQKLDPQRTDAGWLGRLLKKRPVFDFAQADFRAL
CHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCHHCC
PFAGASFDLLWSNLALHWDPAPHAIFPEWHRITTEGGLLMFSLFGPDTLRELRSALAGID
CCCCCHHHHHHHCCEEEECCCCCCCCCCHHEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AGVHTLRFVDMHDIGDMLVHSRWSTPVMDMEQITITYETPQALLADVHLLGGMAGLTDEA
CCHHHEEEECHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCC
GHSLAGAGLHTPRWRQRLFDAFDAQRNPDGLIPLTFEIVYGHAWKLAPTQRQALDEQGRA
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEEECCCHHHHHHHHCCCE
MIPIDQIGRKPRA
EECHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA